Clinical Trials on Atherosclerotic Plaque in Netherlands

Total 167 results

Marc van Sambeek
Eindhoven University of Technology

Unknown

Photoacoustic Imaging of Atherosclerotic Plaques

Carotid Artery Plaque

Netherlands
Maastricht University Medical Center

Recruiting

Molecular Imaging of Plaque Vulnerability (PARISK)

Plaque, Atherosclerotic

Netherlands
Maastricht University Medical Center
Dutch Heart Foundation; Center for Translational Molecular Medicine

Completed

ParisK: Correlation of Imaging Techniques With Histology (ParisK)

Stroke | Plaque, Atherosclerotic

Netherlands
Radboud University Medical Center
Dutch Diabetes Research Foundation

Terminated

Heme Oxygenase (HO) Activity and Adenosine Induced Vasodilation

Atherosclerotic Cardiovascular Disease

Netherlands
University Hospital Inselspital, Berne
Regeneron Pharmaceuticals

Completed

Vascular Effects of Alirocumab in Acute MI-Patients (PACMAN-AMI)

Coronary Circulation | Atheroma; Myocardial | Coronary Vessel

Denmark, Switzerland, Austria, Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...
Merck Sharp & Dohme LLC

Unknown

Study to Investigate the Sensitivity and Specificity of 3.0 Tesla MRI for Carotid Artery Plaque

Atherosclerosis

Netherlands
NHS National Waiting Times Centre Board
Stanford University; Catharina Ziekenhuis Eindhoven; Onze Lieve Vrouw Hospital; Brno University Hospital and other collaborators

Completed

Fractional Flow Reserve (FFR) Versus Instant Wave-Free Ratio (iFR)

Coronary Artery Disease | Plaque, Atherosclerotic

Netherlands, United States, Czech Republic, Belgium, Sweden
Radboud University Medical Center
Dutch Heart Foundation

Completed

Time Restricted Eating and Innate Immunity (SIGNATURE)

Myocardial Infarction | Atherosclerotic Cardiovascular Disease | Time Restricted Feeding

Netherlands
Clinical Operations WCN B.V.
Sanofi

Enrolling by invitation

Comparison of Two Lipid Management Strategies in Very High Risk Patients (PENELOPECTRL)

Atherosclerotic Cardiovascular Disease | STEMI | Non STEMI

Netherlands
Catharina Ziekenhuis Eindhoven
Erasmus Medical Center; Dutch Heart Foundation; Maxima Medical Center

Not yet recruiting

Mind Our Heart Study

Myocardial Infarction | Heart Failure | Peripheral Arterial Disease | Atherosclerotic Cardiovascular Disease

Netherlands
Canisius-Wilhelmina Hospital

Terminated

Plaque Stabilization and Restoration by Bioresorbable Vascular Scaffold

Vulnerable Plaque

Netherlands
Novo Nordisk A/S

Completed

A Research Study Looking at How NNC0385-0434 Tablets Work to Lower Blood Cholesterol in People With Heart Disease or a High Risk of Heart Disease

Atherosclerotic Cardiovascular Disease

Germany, Poland, United States, Netherlands, Japan, Greece, Belgium
Idera Pharmaceuticals, Inc.

Completed

A 12-week Dose-Ranging Trial in Patients With Moderate to Severe Plaque Psoriasis (8400-201)

Plaque Psoriasis

Netherlands
EIP Pharma Inc

Completed

A PET Study of the Effects of p38 MAP Kinase Inhibitor, VX-745, on Amyloid Plaque Load in Alzheimer's Disease (AD)

Mild Cognitive Impairment | Alzheimer's Disease

Netherlands
Eli Lilly and Company

Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Elevated Lp(a) | Atherosclerotic Cardiovascular Disease (ASCVD)

Taiwan, United States, Spain, Argentina, China, Italy, Australia, France, Canada, Japan, Belgium, Denmark, Germany, Hungary, Israel, Austria, Korea, Republic of, Brazil, Mexico, Netherlands, Romania, United Kingdom, Greece, Czechia, India, Slovak... and more
Almirall, S.A.
Harrison Clinical Research; Almirall Hermal GmbH

Completed

LAS41008 in Moderate to Severe Chronic Plaque Psoriasis

Plaque Psoriasis

Austria, Germany, Netherlands, Poland
NewAmsterdam Pharma
Monash University

Recruiting

Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease (PREVAIL)

Atherosclerotic Cardiovascular Disease

United States, Israel, Italy, Spain, Canada, Czechia, Poland, China, Denmark, Netherlands, Finland, Japan, Australia, Hungary, Germany, Croatia, United Kingdom, Bulgaria, South Africa, Georgia, Jordan, Slovakia, Latvia
Amgen

Active, not recruiting

Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial

Atherosclerotic Cardiovascular Disease

United States, Belgium, Spain, China, Korea, Republic of, Australia, Netherlands, Austria, Czechia, Taiwan, Italy, Portugal, Greece, Hong Kong, Hungary, United Kingdom, France, Bulgaria, Germany, Finland, Japan, Sweden, Canada, Denmark, Icelan... and more
Esperion Therapeutics, Inc.

Completed

Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony)

Hypercholesterolemia | Atherosclerotic Cardiovascular Diseases

United States, United Kingdom, Germany, Poland, Netherlands, Canada
Radboud University Medical Center
Canisius-Wilhelmina Hospital

Completed

Epigenetic Reprogramming of Monocytes in Patients With Coronary Atherosclerosis

Atherosclerosis

Netherlands
Erasmus Medical Center

Recruiting

Addition of FFRct in the Diagnostic Pathway of Patients With Stable Chest Pain (Fusion)

Chest Pain | Epicardial Plaques

Netherlands
Amgen

Completed

A Cross-sectional Study of Lipoprotein(a) Levels in Patients With Documented History of Atherosclerotic Cardiovascular Disease (ASCVD)

Atherosclerotic Cardiovascular Disease

Canada, United States, Belgium, Spain, China, Korea, Republic of, Australia, Netherlands, Austria, Czechia, Taiwan, Hungary, Italy, Portugal, United Kingdom, Greece, Hong Kong, Turkey, France, Bulgaria, Germany, Finland, Japan, Sweden, ... and more
Radboud University Medical Center
Amgen

Recruiting

Functional Improvement of Coronary Artery Narrowing by Cholesterol Reduction With a PCSK9 Antibody (FITTER)

Coronary Artery Disease | Atherosclerosis of Coronary Artery

Netherlands
Novartis Pharmaceuticals

Recruiting

A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.

Primary Prevention of Atherosclerotic Cardiovascular Disease

United States, China, Italy, Spain, France, Netherlands, Poland, Switzerland, Taiwan, Greece, Thailand, Brazil, India, Hungary, Latvia, Mexico, Israel, Malaysia, Turkey, Argentina, Singapore, Australia, Belgium, Bulgaria, Denmark, Croatia, South... and more
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Dotatate to Locate Coronary Plaques at High-risk of Myocardial Infarction (DOLPHIN)

Atheroscleroses, Coronary

Netherlands
Novartis Pharmaceuticals

Active, not recruiting

Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease (VICTORION-2P)

Atherosclerotic Cardiovascular Disease

United States, China, South Africa, Spain, Austria, Belgium, Croatia, Estonia, Hungary, Taiwan, Turkey, Netherlands, Italy, Australia, Czechia, Denmark, France, Israel, Korea, Republic of, Thailand, Argentina, Bulgaria, Greece, Romania, Sloveni... and more
Radboud University Medical Center
Erasmus Medical Center; AIDS Malignancy Consortium

Completed

The Effect of Statin Treatment on Trained Innate Immunity (SIMPEL)

Atherosclerosis

Netherlands
UMC Utrecht
University of Aberdeen; Lipid Nutrition B.V; Center Novem

Completed

Conjugated Linoleic Acid and Atherosclerosis

Atherosclerosis

Netherlands
Sanofi

Terminated

Atherosclerosis Underlying Development Assessed by Intima-Media Thickness in Patients on Rimonabant (AUDITOR)

Arteriosclerosis | Obesity | Carotid Artery Plaque | Metabolic Syndrome X

United States, France, Canada, Netherlands, Spain, United Kingdom
Radboud University Medical Center
Rijnstate Hospital

Not yet recruiting

Carotid Artery Plaque Vulnerability Assessment Using Ultrafast Ultrasound Techniques (CAP-VALUE)

Carotid Artery Plaque

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...
Merck Sharp & Dohme LLC

Completed

Technical Innovation Protocol for MR & US Plaque Imaging: Reproducibility.

Atherosclerosis

Netherlands
Radboud University Medical Center

Recruiting

Ultrasound Elastography for Individual Carotid Plaque Stratification (Ultra-COMPASS)

Carotid Artery Plaque

Netherlands
Radboud University Medical Center

Completed

Is Augmentation of PORH by Rosuvastatin Adenosine-receptor Mediated?

Cardiovascular Disease | Atherosclerosis

Netherlands
Almirall, S.A.

Active, not recruiting

Observational Study of Tildrakizumab in Patients With Moderate to Severe Plaque Psoriasis in Routine Clinical Practice (SAIL)

Plaque Psoriasis

Germany, Austria, Italy, Netherlands
Maastricht University Medical Center

Recruiting

Multi-contrast Versus Multi-sequence Carotid MRI

Atherosclerosis

Netherlands
Radboud University Medical Center
Canisius-Wilhelmina Hospital

Completed

The Role of Stem Cells on Immune Cells in the Development of Cardiovascular Diseases (ATHEROSTEM)

Cardiovascular Diseases | Atherosclerosis

Netherlands
Maastricht University Medical Center

Completed

Effects of Omega-3 Fatty Acids and Menaquinone-7 on Thrombotic Tendency

Atherosclerosis

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Unknown

A Proof of Concept Study to Determine the Local Delivery and Efficacy of Nanocort (DELIVER)

Atherosclerosis

Netherlands
Novartis Pharmaceuticals

Completed

An Extension Trial of Inclisiran in Participants With Cardiovascular Disease and High Cholesterol (ORION-3)

Type2 Diabetes | Familial Hypercholesterolemia | Atherosclerotic Cardiovascular Disease | Symptomatic Atherosclerosis

Germany, United Kingdom, Netherlands, United States, Canada
Maastricht University Medical Center

Unknown

18F-Flutemetamol and Plaque Vulnerability

Atherosclerosis

Netherlands
AstraZeneca
The Cleveland Clinic; IQVIA RDS Inc.

Completed

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia (STRENGTH)

Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)

United States, Belgium, Italy, Netherlands, Denmark, Taiwan, Poland, Russian Federation, Korea, Republic of, Hungary, United Kingdom, China, New Zealand, Czechia, Australia, South Africa, Ukraine, Japan, Canada, Mexico, Lithuania, Estoni...
Academisch Medisch Centrum - Universiteit van Amsterdam...

Unknown

Silencing Inflammatory Activity by Injecting Nanocort in Patients at Risk for Atherosclerotic Disease (SILENCE)

Inflammation | Atherosclerosis

Netherlands
Radboud University Medical Center
Erasmus Medical Center; Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Effect of Statins on Trained Immunity

Atherosclerosis

Netherlands
Rijnstate Hospital

Completed

Blood Flow Quantification Near Stented SFA Lesions Using Ultrasound Velocimetry (EchoPIV in SFA)

Peripheral Arterial Disease

Netherlands
Diagram B.V.
Isala; St. Jude Medical Nederland B.V.

Completed

Optical Coherence Tomography Morphologic and Fractional Flow Reserve Assessment in Diabetes Mellitus Patients (COMBINE)

Coronary Artery Disease | Diabetes Mellitus | Coronary Atheroscleroses

Netherlands
RWTH Aachen University

Terminated

Effect of Linagliptin on Vascular Inflammation in Patients With Type 2 Diabetes Mellitus (Lina-Plaque)

Diabetes Mellitus Type 2 (T2DM) | Vascular Inflammation | Plaque Morphology

Germany, Netherlands
Rijnstate Hospital

Enrolling by invitation

Individual Patient Data Analysis of Viabahn for Peripheral Arterial Disease (Insight-VSX)

Peripheral Vascular Diseases

Netherlands
Ionis Pharmaceuticals, Inc.

Active, not recruiting

A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia

Cardiovascular Diseases | Atherosclerosis | Hypertriglyceridemia

United States, Spain, Italy, Denmark, Hungary, Netherlands, Canada, France, Poland, Bulgaria, Czechia, Portugal, Slovakia, Norway
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Chronisch... and other collaborators

Recruiting

Using KomPas+ in the Treatment of Patients With Intermittent Claudication

Peripheral Arterial Disease | Intermittent Claudication

Netherlands
Radboud University Medical Center

Completed

DUAL Pathway Inhibition to Improve Endothelial Function in Peripheral Artery Disease (DUAL-PAD)

Peripheral Artery Disease

Netherlands

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