Clinical Trials on Cognitive Decline

Total 4833 results

Rsocialform - Geriatria, Lda
Aveiro University

Completed

Effect of Individual Cognitive Stimulation on Memory and Executive Function in Older Adults With Alzheimer's Disease

Neurocognitive Disorders | Cognitive Impairment | Cognitive Dysfunction | Dementia | Cognitive Decline

Portugal
University of Kansas Medical Center
National Institute on Aging (NIA)

Completed

Feasibility Trial of a Mediterranean Diet Pattern to Prevent Cognitive Decline

Cognitive Impairment | Alzheimer's Disease

United States
Johns Hopkins University

Withdrawn

Feasibility and Efficacy of Dietary Interventions for Older Adults With Subjective Cognitive Decline

Cognitive Impairment | Alzheimer Disease
University of Kansas Medical Center
National Institute on Aging (NIA)

Completed

Remote Monitoring and Virtual Collaborative Care For Hypertension Control To Prevent Cognitive Decline (vCCC)

Hypertension | Cognitive Decline

United States
Oslo University Hospital
University Hospital of North Norway; UMC Utrecht; Sahlgrenska University Hospital... and other collaborators

Recruiting

Dexmedetomidine or Clonidine Infusion for Prevention of Delirium After Open Heart Surgery (ALPHA2PREVENT)

Delirium | Frailty | Cognitive Decline

Norway
Fundacion CITA-alzheimer
Biogipuzkoa Health Research Institute

Completed

GOIZ ZAINDU Feasibility Multi Domain Trial to Prevent Dementia. (GOIZ_ZAINDU)

Cognitive Decline | Prevention | Dementia Risk Factors | Multidomain Intervention

Spain
Baker Heart and Diabetes Institute

Not yet recruiting

Reducing Cognitive Impairment by Management of Heart Failure as a Modifiable Risk Factor (Cog-HF)

Heart Failure | Cognitive Impairment | Dementia | Cognitive Change | Cognitive Decline | Left Ventricular Dysfunction
Azienda Ospedaliero-Universitaria Careggi
University of Florence; Fondazione Don Carlo Gnocchi Onlus; Scuola Superiore...

Recruiting

PRedicting the EVolution of SubjectIvE Cognitive Decline to Alzheimer's Disease With Machine Learning (PREVIEW)

Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline

Italy
C2N Diagnostics

Completed

Quality Improvement PrecivityAD Clinician Survey (QUIP I) (QUIP I)

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline

United States
Washington University School of Medicine
University of California, San Diego; National Institutes of Health (NIH); National...

Active, not recruiting

Resilience and Brain Health of Older Adults During the COVID-19 Pandemic (MEDEX-2) (MEDEX-2)

Age-related Cognitive Decline

United States
Sunnybrook Health Sciences Centre

Recruiting

Redesigning the Surgical Pathway (PROMoTE) (PROMoTE)

Delirium | Cognitive Impairment | Cognitive Dysfunction | Cognitive Decline | Perioperative/Postoperative Complications

Canada
Taipei Medical University Shuang Ho Hospital

Completed

The Effects of Intermittent Theta Burst Stimulation in MCI and Early AD

Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline

Taiwan
Neurotrack Technologies, Inc.
National Institute on Aging (NIA); University of Arkansas

Active, not recruiting

Reducing Dementia Risk With Digital Health Coaching (DC-MARVEL)

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline

United States
C2N Diagnostics

Recruiting

Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey (QUIP II)

Cognitive Impairment | Dementia | Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline | Memory Impairment

United States
QuesGen Systems Inc

Completed

Reversal of Cognitive Decline (ReCODE) Study (RECODE)

Alzheimer Disease | Mild Cognitive Impairment

United States
University of Pennsylvania
National Institute on Aging (NIA)

Completed

Arterial Spin Labeling (ASL) MRI for Cognitive Decline

Mild Cognitive Impairment | Alzheimer's Disease

United States
Union College, New York
US Department of Veterans Affairs

Completed

Effects of Strengthening Exercise on the Brain for Early Dementia and Normative Older Adults

Dementia | Mild Cognitive Impairment | Cognitive Decline | Alzheimer's Disease

United States
University of Nottingham
Biotechnology and Biological Sciences Research Council

Recruiting

Multi-organ Responses to CHronic Physical Activity and INactivity (CHAIN)

Metabolic Syndrome | Sedentary Behavior | Age-related Cognitive Decline | Age-Related Sarcopenia

United Kingdom
Nicolai Goettel

Recruiting

Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool (CogCheck-Valid)

Cognitive Impairment | Cognition Disorders | Postoperative Delirium | Postoperative Cognitive Dysfunction | Cardiac Surgery | Cognitive Decline

Switzerland
Vanderbilt University Medical Center
University of Pittsburgh; Emory University; Rutgers University; University of Pittsburgh...

Recruiting

Dopaminergic Dysfunction in Late-Life Depression (D3)

Depressive Disorder, Treatment-Resistant | Cognitive Decline | Late Life Depression | Gait Impairment | Levodopa

United States
Wageningen University
Erasmus Medical Center; Amsterdam UMC, location VUmc; ZonMw: The Netherlands... and other collaborators

Unknown

Vitamin B12 and Folic Acid Supplementation for Preventing Fractures in Elderly People (B-PROOF)

Osteoporosis | Cognitive Decline

Netherlands
VA Office of Research and Development

Completed

Complementary Neurosteroid Intervention in Gulf War Illnesses (GWVI)

Fatigue | Musculoskeletal Pain | Cognitive Decline

United States
Aarhus University Hospital
University of Aarhus

Completed

Informant Questionaire on Cognitive Decline in the Elderly (IQCODE) and Delirium in Geriatric Patients (Delirium)

Cognitive Decline | Delirium in Old Age

Denmark
Barcelonabeta Brain Research Center, Pasqual Maragall...

Recruiting

Longitudinal Study for the Characterization of the Phases of Subjective Perception of Cognitive Decline and Mild Cognitive Impairment of Alzheimer's Disease.

Alzheimer Disease | Mild Cognitive Impairment | Subjective Cognitive Decline

Spain
Barcelonabeta Brain Research Center, Pasqual Maragall...

Completed

BarcelonaBeta Dementia Prevention Research Clinic: a Study on Risk Factors Disclosure

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Subjective Cognitive Decline

Spain
University Medicine Greifswald

Completed

Cognitive Training and Brain Stimulation in Prodromal Alzheimer's Disease (AD-Stim)

Mild Cognitive Impairment | Subjective Cognitive Decline

Germany
University of Texas at Austin

Recruiting

Cognitive Screening Made Easy for PCPs - R33 Phase

Cognitive Impairment | Cognitive Decline | Dementia, Mild

United States
University of California, San Diego

Recruiting

Brain Health Virtual Reality Study

Cognitive Change | Aging | Mild Cognitive Impairment | Cognitive Decline | Memory Disorders | Memory Impairment | Cognition Disorders in Old Age | Aging Problems | Memory Loss | Memory Disorders in Old Age | Memory Disorder, Spatial

United States
Heart and Brain Research Group, Germany

Recruiting

Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients. (DESTRESS-SURG)

Postoperative Delirium | Postoperative Cognitive Dysfunction | Preoperative Stress

Germany
University of Cagliari

Completed

Active Ageing and Health

Quality of Life | Physical Activity | Chronic Disease | Aging | Cognitive Decline

Italy
Heart and Brain Research Group, Germany

Recruiting

Increasing Preoperative Cognitive Reserve to Prevent Postoperative Cognitive Dysfunction in Cardiac Surgical Patients (INCORE)

Postoperative Delirium | Postoperative Cognitive Dysfunction | Postoperative Cognitive Decline

Germany
McGill University Health Centre/Research Institute...

Not yet recruiting

The Effect of Intranasal Insulin Administration on Cognitive Function After Cardiac Surgery.

Heart Diseases | Delirium | Cognitive Decline
Karolinska University Hospital
Karolinska Institutet; Fingers Brain Health Institute; af Jochnick Foundation

Recruiting

COGNIFOOD-Changing the Carbohydrate/Fat-ratio to Prevent Cognitive Decline and Alzheimer Pathology: A Pilot Study

Neurocognitive Disorders | Alzheimer Disease | Mild Cognitive Impairment | Prodromal Alzheimer's Disease

Sweden
Barcelonabeta Brain Research Center, Pasqual Maragall...

Recruiting

β-AARC: Cohort Study for the Identification of Blood-based Biomarkers in a Population With Subjective Cognitive Decline (β-AARC)

Alzheimer Disease | Mild Cognitive Impairment | Preclinical Alzheimer

Spain
University of California, San Francisco
National Institute on Aging (NIA)

Recruiting

Napping, Sleep, Cognitive Decline and Risk of Alzheimer's Disease

Cognitive Impairment | Sleep | Alzheimer Disease | Aging | CBT

United States
University Hospital, Tours

Completed

PET Imaging of the Translocator Proteine Ligands (TSPO) With [18 F] DPA-714 Biomarker of NeuroInflammation in Cognitive Decline (NIDECO) (NIDeCo)

Alzheimer Disease | Mild Cognitive Impairment | Memory Complaint

France
Albert Einstein College of Medicine
National Institute on Aging (NIA)

Completed

Movement Intervention for Memory Enhancement (MIME)

Cognitive Impairment | Dementia | Alzheimer Disease | Cognitive Decline | Dementia, Alzheimer Type

United States
Duke-NUS Graduate Medical School
Singapore General Hospital; Agency for Science, Technology and Research; Singapore... and other collaborators

Completed

Effectiveness of a Brain-Computer Interface Based System for Cognitive Enhancement in the Normal Elderly (3ECog)

Dementia | Mild Cognitive Impairment | Alzheimer's Disease | Age-Related Cognitive Decline

Singapore
Mantis Photonics AB
Blekinge County Council Hospital; Blekinge Institute of Technology

Not yet recruiting

Hyperspectral Retinal Observations for the Cross-sectional Detection of Alzheimer's Disease

Cognitive Impairment | Cognitive Decline | Alzheimer Disease, Early Onset

Sweden
University Hospital, Akershus
BASF AS; Pre Diagnostics AS

Unknown

High Dose Omega 3 in People at Risk for Dementia

Pathologic Processes | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Inflammation | Neurocognitive Disorders | Cognitive Dysfunction | Dementia | Cognition Disorders | Mild Cognitive Impairment | Cognitive Decline | SCD | Mental Disorder

Norway
University of California, San Francisco
National Institute on Aging (NIA)

Completed

Impact of Musical Improvisation Training on Cognitive Function in Older Adults

Cognitive Impairment | Aging | Mild Cognitive Impairment | Cognitive Training | Cognitive Aging | Cognitively Normal Older Adults

United States
University of Alberta

Not yet recruiting

SCGs as a Proxy for Determining the Cognitive Status of Older Adults

Dementia | Alzheimer Disease | Healthy Aging | Mild Cognitive Impairment | Cognitive Decline
Shaanxi Hospital of Traditional Chinese Medicine

Recruiting

Technical R&D and Demonstration of Intelligent Medical Care in Alzheimer's Disease's Management

Alzheimer Disease | Mild Cognitive Impairment | Mild Dementia | Subjective Cognitive Decline

China
Rigshospitalet, Denmark
University of Copenhagen; Herlev Hospital

Completed

Identification of Predictors for Early Cognitive Decline in Men

Alzheimer Disease | Mild Cognitive Impairment | Healthy Test Persons

Denmark
Erasmus Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Terminated

Haloperidol for Delirium in Adult Critically Ill Patients (EuRIDICE)

Delirium | Critical Illness | Cognitive Impairment | Cognitive Decline | Intensive Care Psychosis

Netherlands
University of Delaware
National Institute on Aging (NIA)

Not yet recruiting

Effects of Acute Pain on Motor Learning in Young vs Older Adults

Aging | Pain, Acute | Motor Activity | Cognitive Decline
Hospices Civils de Lyon

Recruiting

Anxiety Related to the Diagnosis of Alzheimer's Disease or Related Diseases (ADIMA)

Cognitive Decline

France
Chinese University of Hong Kong

Recruiting

Cognitive Decline in AD

Alzheimer Disease

Hong Kong
Parc de Salut Mar
Barcelonabeta Brain Research Center, Pasqual Maragall Foundation; Hospital...

Completed

Prevention of Cognitive Decline in ApoE4 Carriers With Subjective Cognitive Decline After EGCG and a Multimodal Intervention ((PENSA))

Alzheimer Disease | Cognitive Decline

Spain
Ali Rezai

Withdrawn

Application of TMS Coupled With VR for Slowing the Rate of Cognitive Decline in Patients With Alzheimer's Disease (TMS_AD)

Alzheimer Disease

United States

Clinical Trials on Cognitive Decline

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