Search clinical trials for: Naloxone lofexidine pretreatment

Total 466 results

Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Recruiting

Assessing a Clinically-meaningful Opioid Withdrawal Phenotype

Opioid Use Disorder | Opioid Withdrawal | Opioid Craving

United States
Reproductive & Genetic Hospital of CITIC-Xiangya

Completed

A Retrospective Study on the Effect of Male Progressive Sperm Count After Semen Pretreatment on ICSI Fertilization Outcome

Sperm Count, Low | Reproductive Sterility

China
Bispebjerg Hospital

Completed

Pretreatments of the Skin Prior to PDT

Healthy
Sahlgrenska University Hospital, Sweden

Completed

Pretreatment Group Consultation for Patients With Colorectal Cancer

Colorectal Neoplasm

Sweden
Samjin Pharmaceutical Co., Ltd.

Completed

A Phase 4 Clinical Study to Investigate the Efficacy and Safety of Naloxone HCI IV in Patients With Stroke

Stroke, Acute

Korea, Republic of
Ain Shams University

Completed

Success Rates for Management of Separated Instruments

Teeth, Endodontically-Treated

Egypt
Xijing Hospital

Completed

Preconditioning With Hyperbaric Oxygen in Cardiovascular Surgery

Myocardial Injury | Brain Injury
Catholic University of the Sacred Heart

Completed

Broken Instrument Removal

Endodontically Treated Teeth | Endodontical Retreatment
Ain Shams University

Completed

Minimally Invasive Management During Endodontic Retreatment

Teeth, Endodontically-Treated

Egypt
University of Bologna

Completed

Retreat or Replace: Retrospective Investigation on a Cohort of Local Patients

Periapical Diseases | Dental Implant Failed | Endodontic Disease
Xijing Hospital

Unknown

Cardioprotective Effects of Electroacupuncture Pretreatment Against Coronary Stenting

Myocardial Injury

China
Dubai Health Authority

Recruiting

Retrospective Assessment of Root Canal Retreatment Performed in Single Visit

Root Canal Retreatment

United Arab Emirates
Universitat Internacional de Catalunya

Recruiting

Outcome of Endodontic Retreatment in One or Two Visits

Endodontic Disease | Endodontically Treated Teeth | Root Canal Infection

Spain
Postgraduate Institute of Dental Sciences Rohtak

Unknown

Comparision of Non Surgical Retreatment and Endodontic Surgery of Failed Root Canal Treated Teeth

Periapical Periodontitis | Root Canal Therapy

India
Judith Feinberg

Unknown

Nasal Naloxone for Narcotic Overdose

Drug Overdose

United States
Xijing Hospital
Air Force Military Medical University, China

Completed

Neuroprotective Study of Electroacupuncture Pretreatment in Patients Undergoing Cardiac Surgery

Stroke | Brain Injuries

China
Ege University

Completed

One and Two-visit Root Canal Retreatment

Root Canal Infection

Turkey
Cairo University

Unknown

Postoperative Pain Endodontic Retreatment

Endodontically Treated Teeth
Shandong University
Shengjing Hospital; General Hospital of Ningxia Medical University; West China... and other collaborators

Not yet recruiting

Effect of Metformin on Healthy Live Birth in Women With Prediabetes (MELT-PreDM)

Prediabetes | Metformin | In-Vitro Fertilization

China
Indiana University

Completed

The Effect of Pretreatment With Roc on Succinylcholine Myalgias

Myalgia

United States
Plus Therapeutics

Not yet recruiting

Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment

Glioma
TC Erciyes University

Completed

Postoperative Pain After the Removal of Root Canal Filling Material

Postoperative Pain
Galderma R&D

Completed

Comparison of Mechanical Penetration Enhancers on Metvixia Skin Penetration

Healthy
mads u werner
University of Kentucky

Completed

Effect of High-dose Naloxone Following Third Molar Extraction (TME)

Pain, Acute | Healthy Subjects | Hyperalgesia | Sensitization, Central | Inflammations, Endodontic

Denmark
mads u werner
University of Kentucky

Completed

Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury (TCI-NX-BI)

Healthy Subjects

Denmark
University of Valencia

Active, not recruiting

Outcomes on Teeth Prepared With BOPT

Outcome | Prosthetic | Soft Tissues
S.L.A. Pharma AG

Completed

Naloxone SR Capsules in Patients With Opioid Induced Constipation

Chronic Pain | Opioid Induced Constipation

Germany, United Kingdom
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray, Naloxone Hydrochloride (HCl) Intravenous (IV) and Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
Pocket Naloxone Corp

Completed

Pharmacokinetic Evaluation of a New Naloxone Nasal Swab, Naloxone Nasal Spray, and Intramuscular Naloxone Injection in Healthy Volunteers

Opioid Overdose

Canada
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Completed

Efficacy, Safety and Dose-Response Study Followed by Open-Label Study of Lofexidine Treatment of Opioid Withdrawal

Opioid Dependence | Acute Opioid Withdrawal Syndrome

United States
Norwegian University of Science and Technology
St. Olavs Hospital; Smerud Medical Research International AS; A/S Den norske...

Completed

Bioavailability of Nasal Naloxone and Injected Naloxone Compared (OPI-15-002)

Drug Overdose

Norway
Critical Therapeutics

Terminated

CTI-01 (Ethyl Pyruvate) Safety and Complication Prevention in Cardiac Surgery Patients on Cardiopulmonary Bypass (CPB)

Coronary Disease | Heart Valve Diseases

United States
Instituto Bernabeu

Not yet recruiting

TRAP Study: Testosterone for Androgen Receptor Polymorphism (TRAP)

Fertility Disorders

Spain
Sun Yat-sen University
First People's Hospital of Foshan; Cancer Research Institute of Zhongshan City

Active, not recruiting

Reducing Target Volumes in NPC Treated With Induction Chemotherapy Followed by Concurrent Chemoradiotherapy (NPC-GTV)

Nasopharyngeal Carcinoma | Radiotherapy | Induction Chemotherapy

China
Bulent Ecevit University

Completed

Releasing of Inflammatory Mediators During Retreatment of Root Canals

Inflammatory Response | Root Canal Infection

Turkey
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray and Naloxone Hydrochloride (HCl) Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Pharmacokinetics and Pharmacodynamics of a New Formulation of Nasal Naloxone for Prehospital Use (OPI-14-001)

Drug Overdose

Norway
Zhejiang Cancer Hospital

Recruiting

DLCS for Predicting Neoadjuvant Chemotherapy Response

Gastric Cancer | Deep Learning | Neoadjuvant Chemotherapy | CT Images | Tumor Regression Grade

China
Hospices Civils de Lyon

Completed

Prosthesis Infection and One-step Exchange: Pretreatment by Targeted Antibiotic Therapy in At-risk Patients

Prosthetic Joint Infection | Antibiotic Resistant Infection

France
Leiden University Medical Center
U.S. Food and Drug Administration (FDA)

Recruiting

Reversal of Opioid-induced Respiratory Depression With Opioid Antagonists (ROAR)

Chronic Opioid Use | Opioid Induced Respiratory Depression

Netherlands
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Completed

A Study Evaluating the Relative Bioavailability of Lofexidine Granules for Reconstitution Compared to LUCEMYRA (Lofexidine) Tablets and the Effect of Food on the Bioavailability of the Lofexidine Granules for Reconstitution

Normal Healthy Volunteers

United States
Duke University
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Completed

Buprenorphine Physician-Pharmacist Collaboration in the Management of Patients With Opioid Use Disorder: CTN 0075 (Pharm-OUD-Care)

Opioid Use Disorder

United States
Norwegian University of Science and Technology
St. Olavs Hospital; University of Iceland

Completed

A Pilot Study of the Bioavailability of Nasal Naloxone

Drug Overdose

Norway
University of Washington

Unknown

Subjective Analgesic Effects of Naloxone and Virtual Reality (Narcan)

Pain

United States
University of Edinburgh
NHS Lothian

Completed

Pain Following Root Canal Treatment (PfRCT)

Assessment of Pain After Root Canal Treatment

United Kingdom
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Completed

Pharmacokinetic & Pharmacodynamic Interaction of Lofexidine and Buprenorphine in Buprenorphine Maintained Patients

Opioid Dependence | Buprenorphine Withdrawal Syndrome

United States
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Recruiting

Pharmacokinetic and Safety Study of Oral Lofexidine in Neonates Experiencing Opioid Withdrawal Due to Intrauterine Exposure to Opioids

Opioid Withdrawal (Disorder)

United States
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Completed

Assessment of the Effect of Naltrexone on Lofexidine Single Dose Pharmacokinetics in Healthy Subjects

Healthy

United States
Parc de Salut Mar
Food and Drug Administration (FDA)

Recruiting

Pharmacokinetics of Intravenous and Intranasal Formulations of Naloxone in Healthy Volunteers.

Healthy

Spain
University of Minnesota

Completed

Naloxone, Hypoglycemia and Exercise

Diabetes Mellitus, Type 1

United States

Search clinical trials for: Naloxone lofexidine pretreatment

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