Search clinical trials for: Bisphosphonates

Total 124 results

Amgen

Completed

Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Men With Hormone-refractory Prostate Cancer

Bone Metastases
Vanderbilt-Ingram Cancer Center

Completed

First Autologous Transplant on Minimal Residual Disease Markers in Previously Untreated Myeloma Undergoing Initial Treatment With Velcade

Multiple Myeloma

United States
Children's Cancer Hospital Egypt 57357

Completed

Zometa Study in Pediatric Acute Lymphoblastic Leukemia

Osteoporosis

Egypt
James J. Peters Veterans Affairs Medical Center
Kessler Institute for Rehabilitation

Completed

Zoledronic Acid Administration in Acute Spinal Cord Injury

Disuse Osteoporosis

United States
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Procter and Gamble

Completed

Bisphosphonate Action on the Appendicular Skeleton: Evidence for Differential Effects

Post-menopausal Osteoporosis

United Kingdom
Gilles Boire
Procter and Gamble

Completed

Assessment of Response to Treatment of Osteoporosis With Oral Bisphosphonates in Patients With Muscular Dystrophy

Muscular Dystrophy | Osteoporosis | Cystic Fibrosis

Canada
The Hospital for Sick Children

Terminated

The Use of Bisphosphonates in the Treatment of Avascular Necrosis of the Femoral Head

Femoral Head Avascular Necrosis

Canada
Società Italiana Talassemie ed Emoglobinopatie

Completed

Vitamin D and Bisphosphonates in the Treatment of Sickle Cell Disease

Sickle Cells Disease

Italy
Region Skane

Completed

Bisphosphonates and Impaction Grafting in Hip Revision

Aseptic Loosening of the Hip Prosthesis

Sweden
GlaxoSmithKline

Completed

Quality of Life(QoL) in Korean Postmenopausal Osteoporosis Patients With Bisphosphonate Treatment (BRAVO)

Osteoporosis, Postmenopausal

Korea, Republic of
University of Alabama at Birmingham
Novartis Pharmaceuticals

Completed

Pilot Study of Bisphosphonate Therapy (Zoledronic Acid) in Patients With Malignant Mesothelioma (UAB 0901) (UAB0901)

Mesothelioma

United States
University of Alabama at Birmingham

Completed

Effectiveness of DiscontinuinG bisphosphonatEs Study: R21 Pilot Study (EDGE)

Osteoporosis

United States
University of Southern California
National Cancer Institute (NCI)

Withdrawn

Genetics in Predicting Risk of Bisphosphonate-Related Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid

Malignant Neoplasm | Musculoskeletal Complications

United States
Turku University Hospital
Novartis; Academy of Finland; Stryker Nordic

Completed

Efficacy of Zoledronic Acid in Enhancement of Early Stability of Cementless Primary Hip Prosthesis

Hip Osteoarthritis

Finland
Novartis Pharmaceuticals

Completed

Effect of Zoledronic Acid on Bone Metabolism in Patients With Bone Metastasis and Prostate or Breast Cancer

Breast Cancer | Prostate Cancer | Bone Metastasis

Germany
Novartis

Completed

Evaluation of Bone Markers as Diagnostic Tools for Early Detection of Bone Metastases in Patients With High Risk Prostate Cancer

Prostate Cancer

Germany
Hoffmann-La Roche

Completed

A Study To Assess the Quality and Strength of Bone in Women Participants With Osteoporosis Taking Oral Ibandronate Versus Placebo

Osteoporosis

United States
GlaxoSmithKline

Completed

A Study To Assess The Quality Of Bone In Patients Taking Oral Ibandronate Versus Placebo

Osteoporosis

United States
Massachusetts General Hospital

Completed

The Effect of Alendronate on the Immune Response to Hepatitis B Vaccine in Healthy Adults

Hepatitis B

United States
Peking Union Medical College Hospital

Completed

Efficacy of Bisphosphonates in Patients With Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome

SAPHO Syndrome
Eunice Kennedy Shriver National Institute of Child...

Completed

Treatment of Childhood Osteoporosis With Alendronate (Fosamax)

Osteoporosis

United States
Novartis Pharmaceuticals

Completed

Intra-venous Zoledronic Acid Once Yearly (IVORY)

Post-Menopausal Osteoporosis

Canada
Eunice Kennedy Shriver National Institute of Child...
National Institutes of Health Clinical Center (CC)

Completed

Pamidronate to Treat Osteogenesis Imperfecta in Children

Osteogenesis Imperfecta

United States
Mayo Clinic

Completed

Osteoporosis Choice Decision Aid for Use of Bisphosphonates in Postmenopausal Women

Osteoporosis | Postmenopausal Osteoporosis | Postmenopausal Bone Loss | Bone Loss, Age Related

United States
National Bone Health Alliance
Roche Pharma AG; National Osteoporosis Foundation

Unknown

Changes in Biochemical Markers of Bone Turnover (Serum CTX and PlNP) After Initiation of a "Drug Holiday" From Bisphosphonates

Osteoporosis

United States
University of Wisconsin, Madison

Withdrawn

Evaluation of the Risk for Radiographic and Clinical Nonunion in Patients With Previous Bisphosphonates Therapy.

Non-union or Delayed Healing Fractures

United States
Damascus University

Completed

Bisphosphonates Effects On Alveolar Bone Among Osteoporotic Women

Osteoporosis

Syrian Arab Republic
Queen's University

Completed

Queen's University Investigation of Calcification in Chronic Kidney Disease (QUICK)

Chronic Kidney Disease

Canada
Instituto Palacios
Pfizer

Completed

Switching From Oral Bisphosphonates to Bazedoxifene to Evaluate Effects on Bone Mineral Density in Postmenopausal Women

Osteoporosis, Postmenopausal

Spain
Tuen Mun Hospital

Completed

Denosumab in Current Users of Bisphosphonates for Glucocorticoid-induced Osteoporosis

Osteoporosis

China
Novartis Pharmaceuticals

Completed

A Study to Evaluate the Safety and Efficacy of Zoledronic Acid in the Prevention or Delaying of Bone Metastasis in Patients With Stage IIIA and IIIB Non-small Cell Lung Cancer (NSCLC)

Non-Small-Cell Lung Cancer

Greece, Taiwan, Germany, Belgium, Italy, Spain, United Kingdom, Korea, Republic of, Netherlands, China, Hungary, Poland, France, Thailand, Portugal
University Hospital, Basel, Switzerland
FAG (Freie Medizinische Gesellschaft)

Withdrawn

Study of Pamidronate for the Prevention of Heterotopic Ossification

Heterotopic Ossification
University of Cologne

Completed

Translational Therapy in Patients With Osteogenesis Imperfecta - A Pilot Trial on Treatment With the Rankl-Antibody Denosumab (OI-AK)

Osteogenesis Imperfecta

Germany
University Health Network, Toronto
AstraZeneca

Completed

Risk Factors for Skeletal Related Events in Breast Cancer Patients Receiving Bisphosphonates for Bone Metastases (PROVISTII)

Breast Cancer | Bone Metastases

Canada
University of Michigan
M.D. Anderson Cancer Center; Memorial Sloan Kettering Cancer Center; National... and other collaborators

Completed

Genetic Risk of Osteonecrosis of the Jaw (ONJ) in Patients With Metastatic Cancer

Bone Diseases | Osteonecrosis | Metastases | Bisphosphonate-Associated Osteonecrosis of the Jaw

United States
Danderyd Hospital
Sanofi

Completed

Can Risedronate Prevent Periprosthetic Bone Loss After Total Hip Arthroplasty (PREVENT)

Bone Loss

Sweden
Micromedic Technologies Ltd

Unknown

Performance Evaluation of the Micromedic BRONJ Risk Assessment in Vitro Diagnostic Assay (BRONJ)

Bisphosphonate-related Osteonecrosis of the Jaw

Israel
Cliniques universitaires Saint-Luc- Université...

Unknown

Prospective Randomized Study: Assessment of PRF Efficacy in Prevention of Jaw Osteonecrosis After Tooth Extraction (PRF)

Bisphosphonate-Associated Osteonecrosis of the Jaw

Belgium
Novartis Pharmaceuticals

Completed

Effect of Zoledronic Acid as Anti-Cancer Treatment in Metastatic Breast Cancer Patients (MACS1295)

First or Second Line HER2-negative Breast Cancer | Metastatic Disease Without Bone Metastasis

United States
University of Sao Paulo General Hospital

Completed

Zoledronic Acid to Prevent Bone Loss After Kidney Transplantation

Renal Osteodystrophy

Brazil
Novartis Pharmaceuticals

Completed

Zoledronic Acid - Letrozole Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women With Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy

Breast Neoplasms | Osteoporosis

United States, Puerto Rico
University of Pittsburgh
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Prevention of Osteoporosis in Men With Prostate Cancer on Androgen Deprivation Therapy (POP Study)

Prostatic Neoplasms

United States
Amgen

Completed

Denosumab (AMG 162) in Bisphosphonate Naive Metastatic Breast Cancer

Breast Cancer | Metastases | Bone Metastases in Subjects With Advanced Breast Cancer
University of Oulu
Novartis Pharmaceuticals

Completed

The Efficacy of Zoledronic Acid in Modic Changes-related Low Back Pain (LBP)

Low Back Pain

Finland
Sun Yat-sen University
Novartis

Completed

Screening Non Small Cell Lung Cancer With Bone Metastasis and Efficacy and Safety Research of Receiving Bisphosphonates (BLEST)

Bone Metastases | Non-small Cell Lung Cancer

China
Hospices Civils de Lyon

Completed

Study to Assess Efficacy of Risedronate in Preventing Bone Loss in Postmenopausal Women Treated for Breast Cancer (RISAROS)

Breast Cancer | Menopause | Osteopenia

France
University of Arkansas

Completed

Bisphosphonate-Associated Jaw Osteonecrosis and PET Imaging

Osteoradionecrosis of the Jaw | Bisphosphonate-associated ONJ | Osteomyelitis of the Jaw | Osteolytic Lesions of the Jaw

United States
Meir Medical Center

Unknown

Compliance and Persistence With Osteoporosis Treatment and Attitude Towards Future Therapy Among Post-menopausal Israeli Women During Drug Treatment or Drug Holiday (CONTINUITY)

Osteoporosis

Israel
University of Alabama at Birmingham
Kaiser Permanente

Completed

Improving Care of Osteoporosis: Multi-Modal Intervention to Increase Testing and Treatment (ICOMMIITT) (ICOMMIITT)

Osteoporosis

United States
Duke University

Completed

Randomized Controlled Trial of Hyperbaric Oxygen in Patients Who Have Taken Bisphosphonates

Osteonecrosis

United States

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