Search clinical trials for: Gastrointestinal impairment

Total 46776 results

Sun Yat-sen University

Completed

Aprepitant Triple Therapy for the Prevention of CINV in Nondrinking and Young Women Who Received Moderately Emetogenic Chemotherapy (CINV)

Gastrointestinal Neoplasms | Chemotherapy-induced Nausea and Vomiting

China
Sahlgrenska University Hospital, Sweden
BioGaia AB

Completed

Prevention of Glucocorticoid Induced Impairment of Bone Metabolism

Bone Loss

Sweden
Celgene

Completed

Study of Pomalidomide to Evaluate the Pharmacokinetics and Safety for Patients With Multiple Myeloma and Impaired Renal Function (POM Renal) (POM Renal)

Multiple Myeloma | Renal Impairment

United States, Canada
University of Oregon
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy

Syndrome | Pain | Muscle Weakness | Tendinopathy | Shoulder Pain | Acute Pain | Impairment | Goals | Pathology | Injury | Infiltration | Atrophic

United States
Intercept Pharmaceuticals
Syneos Health; Global PBC Study Group; Target RWE; UK PBC Group

Completed

Real-World Data Study to Evaluate the Effectiveness of OCA on Hepatic Outcomes in PBC Patients (HEROES PBC)

Primary Biliary Cholangitis

United States
University Health Network, Toronto
Marianjoy Rehabilitation Hospital & Clinics

Terminated

Tongue Pressure Resistance Training for Swallowing Impairment Post-Stroke (TPRT-SIPS)

Stroke | Dysphagia

Canada, United States
Celgene

Completed

A Phase 1, Multicenter, Open-Label Study to Evaluate the Effect of Mild or Moderate Hepatic Impairment on the Multiple-Dose Pharmacokinetics of Ozanimod

Liver Diseases | Digestive System Diseases

United States
Universitätsklinikum Hamburg-Eppendorf

Completed

Daratumumab in Combination With Bortezomib and Dexamethasone in Subjects With Relapsed or Relapsed and Refractory Multiple Myeloma and Severe Renal Impairment (GMMG-DANTE)

Multiple Myeloma

Germany, Greece
University of Florida

Withdrawn

Dysphagia in Cardiac Surgical Patients_

Cardiovascular Diseases
Erasmus Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Terminated

Haloperidol for Delirium in Adult Critically Ill Patients (EuRIDICE)

Delirium | Critical Illness | Cognitive Impairment | Cognitive Decline | Intensive Care Psychosis

Netherlands
Astellas Pharma Global Development, Inc.

Completed

A Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic Medication

Schizophrenia

United States
Georgetown University

Completed

Single-dose PK Assessment of Oral Proglumide in Those With Hepatic Impairment (HIPK)

Cirrhosis, Liver

United States
Northern Arizona University

Completed

Impact of Swallowing Impairment on Individuals With Parkinson Disease

Parkinson Disease | Dysphagia

United States
Queen's University, Belfast
Belfast Health and Social Care Trust; Cancer Research Network

Terminated

An Intervention Programme to Reduce Cognitive Impairment Due to Cancer

Breast Neoplasms | Colorectal Neoplasms

United Kingdom
University of Florida

Completed

Dysphagia in Thoracic Surgical Patients

Thoracic Diseases

United States
The University of Hong Kong

Completed

Effectiveness of Walking Exercise in Improving Cognitive Function in Older Adults With Mild Cognitive Impairment

Mild Cognitive Impairment

Hong Kong
University of Washington
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institute... and other collaborators

Completed

A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity (TSOS6)

Substance-Related Disorders | Depression | Alcohol-Related Disorders | Quality of Life | Pain | Brain Injuries | Chronic Disease | Suicidal Ideation | Mild Cognitive Impairment | Posttraumatic Stress Disorder | Wounds and Injury

United States
Shire

Completed

Pharmacokinetics (PK) of 20 mg Teduglutide in Participants With Moderately Impaired Hepatic Function Compared to Healthy Participants

Hepatic Impairment

United States
National Hepatology & Tropical Medicine Research...

Completed

Norepinephrine Infusion Versus Midodrine & Octreotide in Patients With Hepatorenal Syndrome Type 1.

Renal Impairment in Hepatorenal Syndrome

Egypt
Galmed Research and Development, Ltd.

Enrolling by invitation

Open-Label Study to Evaluate the Safety, Tolerability, and PK of Aramchol in Subjects With Hepatic Impairment

Hepatic Impairment

United States
Riphah International University

Completed

Providing Speech Therapy Awareness in Private Schools

Head and Neck Cancer | Stuttering | Hearing Impairment | Swallowing Disorder | Speech Therapy | Developmental Delay Disorder | Speech Delay | Speech and Language Disorder | Acquired Language Disorders

Pakistan
Allergan

Completed

Chart Review: Drug Utilization Study in Participants Who Received Ozurdex™ (Dexamethasone Intravitreal Implant) 0.7 mg Injections for Visual Impairment Due to Diabetic Macular Edema (DME)

Diabetic Macular Edema

United States
Ipsen

Completed

To Determine the Effect of Forlax® Treatment in Children With Chronic Constipation Who May Also Suffer From Soiling/ Faecal Incontinence.

Chronic Constipation

Thailand
Central Hospital, Nancy, France
University of Lorraine

Unknown

Prevalence of Respiratory Impairment During IBD (PARAMICI)

Bronchiectasis | Chronic Obstructive Pulmonary Disease | Inflammatory Bowel Diseases | Asthma
Eisai Inc.
Purdue Pharma LP

Completed

Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Mild and Moderate Hepatic Impairment Compared to Healthy Subjects

Hepatic Impairment

United States
Eisai Inc.
Purdue Pharma LP

Completed

Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Normal Renal Function or With Severe Renal Impairment

Renal Impairment

United States
Karolinska University Hospital
Ullevaal University Hospital; Oslo University Hospital; Sahlgrenska University... and other collaborators

Completed

Neoadjuvant Chemotherapy Versus Radiochemotherapy for Cancer of the Esophagus or Cardia (NeoRes)

Carcinoma, Squamous Cell | Adenocarcinoma of the Esophagus and Gastric Cardia

Sweden
Marion Coe
National Institute on Drug Abuse (NIDA)

Completed

Sedative-Anxiolytic Effects on Simulated Driving Performance

Psychomotor Impairment

United States
Theranexus

Completed

A Pharmacodynamics, Safety, and Pharmacokinetics Study of THN201 Versus Donepezil in Healthy Male Volunteers

Cognitive Impairment | Alzheimer Disease

France
Azienda Ospedaliero-Universitaria Careggi
MDM S.p.A.

Completed

Choline Alphoscerate-Nimodipine in Vascular Cognitive Impairment (CONIVAD)

Vascular Cognitive Impairment

Italy
Roswell Park Cancer Institute

Completed

Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Graft Versus Host Disease

United States
M.D. Anderson Cancer Center
Celgene Corporation

Terminated

Lenalidomide Combined With Vorinostat/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Diffuse Large B-Cell Lymphoma of the ABC Subtype

Lymphoma

United States
Vanderbilt University Medical Center

Completed

The Modifying the Impact of ICU-Associated Neurological Dysfunction-USA (MIND-USA) Study (MIND-USA)

Delirium | Impaired Cognition | Long Term Psychologic Disorders

United States
Takeda

Terminated

TAK-071 Scopolamine-Induced Cognitive Impairment Study

Healthy Volunteers

United States
AbbVie

Completed

A Study to Evaluate the Efficacy and Safety of Glecaprevir/Pibrentasvir in Adults With Chronic Hepatitis C Virus Genotype 1 - 6 Infection and Renal Impairment (EXPEDITION-5)

Hepatitis C Virus (HCV)

United States, Canada, Germany, Greece, Italy, Korea, Republic of, Poland, Puerto Rico, Spain, Sweden
Kyowa Hakko Bio Co., Ltd.
Biofortis Clinical Research, Inc.

Completed

Cognitive Effects of Citicoline in Men and Women With Age-Associated Memory Impairment

Healthy

United States
Vanderbilt University Medical Center

Completed

Mental Ability Challenge Study in Adults With and Without HIV

Cognitive Impairment | Memory Impairment | HIV-1-infection | Aging, Premature | HIV-Associated Cognitive Motor Complex

United States
University of Sao Paulo

Completed

Multimodal Analysis and Electroretinogram in VKH From Acute Onset - Part I

Inflammation | Visual Impairment | Uveomeningoencephalitic Syndrome | Choroid Disease

Brazil
Gorm Greisen

Completed

Long-term Consequences of Necrotizing Enterocolitis in the Newborn Period

Complications | NEC - Necrotizing Enterocolitis

Denmark
Tetra Discovery Partners

Completed

Study to Evaluate the Effects of BPN14770 on Scopolamine-induced Cognitive Impairment in Healthy Volunteers

Alzheimer Disease

United States
Vanderbilt University

Completed

MENDS Study: Trial in Ventilated ICU Patients Comparing an Alpha2 Agonist Versus a Gamma Aminobutyric Acid (GABA)-Agonist to Determine Delirium Rates, Efficacy of Sedation, Analgesia and Discharge Cognitive Status

Delirium

United States
Indiana University
National Institute on Aging (NIA)

Completed

Pharmacological Management of Delirium (PMD)

Delirium | Cognitive Impairment

United States
Sichuan University

Unknown

Chidamide Combined With Clad/Gem/Bu With AutoSCT in R/R Diffuse Large B Cell Lymphoma

Lymphoma

China
First Affiliated Hospital of Zhejiang University

Completed

To Explore Cognitive Neural Mechanism of Autoimmune Encephalitis by Using Neuropsychological Tests and Multi-modal MRI

Cognitive Impairment | Autoimmune Encephalitis

China
Institute of Liver and Biliary Sciences, India

Completed

Effect of Goal Directed Ammonia Lowering Therapy in Acute on Chronic Liver Failure Patients With Hepatic Encephalopathy.

Acute-On-Chronic Liver Failure

India
Faisal_Karmali@MEEI.HARVARD.EDU
Massachusetts Institute of Technology; National Space Biomedical Research Institute

Completed

Countermeasures to Reduce Sensorimotor Impairment and Space Motion Sickness Resulting From Altered Gravity Levels

Vestibular

United States
Scuola Superiore Sant'Anna di Pisa
Unit of Developmental Neurorehabilitation, Pisa University Hospital

Completed

Immersive Virtual Environments and Wearable Haptic Devices in Rehabilitation of Children With Neuromotor Impairments (SERIOUSGAME)

Cerebral Palsy | Dyspraxia

Italy
GlaxoSmithKline

Completed

Observational Study Evaluating The Processing Or Breakdown Of GW679769 In Subjects With Hepatic Impairment

Vomiting

United States
Dana-Farber Cancer Institute
Massachusetts General Hospital; Pharmacia; Brigham and Women's Hospital

Completed

Cisplatin, CPT-11 and Celecoxib With Radiation Therapy and Surgery for Operable Esophageal Cancer

Esophageal Cancer

United States
PTC Therapeutics

Completed

A Single Dose Evaluation of the Effects of Moderate Hepatic Impairment on Deflazacort Pharmacokinetics

Hepatic Impairment

United States

Search clinical trials for: Gastrointestinal impairment

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