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Dual Task Gait Performance in Pediatric Oncology Patients

2. marts 2021 opdateret af: Emel Taşvuran Horata, Afyonkarahisar Health Sciences University

Comparison of Single and Dual Task Gait Performance in Pediatric Oncology Patients With Healthy Control Group

Cancer incidence, which is recognized as the leading cause of death in children worldwide, is gradually increasing.

Most studies on children who survive cancer show that the disease and its treatment have side effects and long-term late effects on the musculoskeletal system, physical function, gait and cognitive skills.

Therefore, dual task gait performance, in which cognitive and motor tasks are performed simultaneously, may be affected in pediatric oncology patients. The aim of this study is to compare gait performance in single and dual task conditions in pediatric oncology patients with healthy controls.

Studieoversigt

Status

Rekruttering

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

Cancer incidence, which is recognized as the leading cause of death in children worldwide, is gradually increasing. About 300,000 children aged 0 to 19 are diagnosed with cancer each year, according to the international study where the International Agency for Research on Cancer collected data on neoplasms (malignant and non-malignant) diagnosed in individuals under 20 years of age between 2001-2010.

Most studies on children who survive cancer show that the disease and its treatment have side effects and long-term late effects on the musculoskeletal system, physical function, gait and cognitive skills. According to the study of Beulertz et al. (2016), active ankle dorsiflexion limitation, gait disturbances and decrease in walking efficiency were observed in all pediatric oncology patients, which have an important role in walking, not limited to children with bone tumors and central nervous system tumors.Intensive chemotherapy (eg methotrexate) and the use of radiation are thought to cause damage to cortical and subcortical white matter, resulting in late effects. Symptoms consistent with attention deficit disorder and mental processing speed, working memory, executive function and memory deficits put cancer survivors at an intellectual and academic disadvantage.

Therefore, dual task gait performance, in which cognitive and motor tasks are performed simultaneously, may be affected in pediatric oncology patients. The aim of this study is to compare gait performance in single and dual task conditions in pediatric oncology patients with healthy controls.

Undersøgelsestype

Observationel

Tilmelding (Forventet)

40

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiekontakt

Studiesteder

  • Kalkun
      • Afyonkarahisar, Kalkun, 03030
        • Rekruttering
        • Emel Taşvuran Horata
        • Kontakt:
        • Kontakt:
        • Ledende efterforsker:
          • EMEL TAŞVURAN HORATA, PhD
        • Underforsker:
          • Hamide Nur ÇEVİK ÖZDEMİR, PhD
        • Underforsker:
          • Yunus Emre KUNDAKCI, PhD
        • Underforsker:
          • İbrahim EKER, PhD

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

6 år til 18 år (Barn, Voksen)

Tager imod sunde frivillige

Ingen

Køn, der er berettiget til at studere

Alle

Prøveudtagningsmetode

Ikke-sandsynlighedsprøve

Studiebefolkning

In this study, inpatient and outpatient children diagnosed with cancer in Afyonkarahisar Health Sciences University Health Application and Research Center Pediatric Hematology-Oncology Clinics will form the case group of the study.

Healthy children who come to Afyonkarahisar Ege Youth and Sports Club Association to do sports and who have recently registered will form the control group of the research.

Beskrivelse

Inclusion Criteria:

Healthy control group:

  • Being in the age range of 6-18,
  • To be physically, cognitively and mentally healthy,
  • Open to communication enough to understand questions,
  • Speaking and understanding Turkish,
  • Approval has been obtained from the child and his / her family for the study and who agrees to participate in the study,

Case group:

  • Able to walk alone without any walking aid,
  • Open to communication enough to understand questions,
  • Speaking and understanding Turkish,
  • Approval has been obtained from the child and his / her family for the study and who agrees to participate in the study,
  • Children between the ages of 6-18 will be included in the study

Exclusion Criteria:

Healthy control group:

  • Any orthopedic or neurological impairment that would prevent walking;
  • Having any mental disability that prevents cognitive task

Case group:

  • Staying in an isolated room or having risk of infection (neutropenic, etc.),
  • Any orthopedic or neurological impairment that could prevent walking;
  • Having any mental disability that prevents cognitive task,
  • Individuals with malignant hypertension or unstable heart disease (eg congestive heart failure) will not be included in the study.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Observationsmodeller: Case-Control
  • Tidsperspektiver: Fremadrettet

Kohorter og interventioner

Gruppe / kohorte
Intervention / Behandling
Healthy Control Group
Healthy children who come to Afyonkarahisar Ege Youth and Sports Club Association for the purpose of sports, newly registered and between the ages of 6-18 will constitute the control group of the study.
Andet: Gait assessment (single)
The single walk will be evaluated with a 10-meter walking test and a G-Walk portable device.
Andet: Dual task gait assessment (motor+motor)
The dual task gait, 10-meter walking test and a motor (carrying a full water glass) will be combined with the task and evaluated with the G-Walk portable device.
Andet: Dual tak gait assessment (motor+cognitive)
The dual task gait will be combined with a 10-meter walking test and a cognitive (1-back test) task and evaluated with the G-Walk portable device.
Case Group
The sample of the study will be inpatient and outpatient pediatric patients between the ages of 6-18 who have been diagnosed with cancer in the Pediatric Hematology-Oncology Clinics of Afyonkarahisar Health Sciences University Health Application and Research Center Department of Pediatrics.
Andet: Gait assessment (single)
The single walk will be evaluated with a 10-meter walking test and a G-Walk portable device.
Andet: Dual task gait assessment (motor+motor)
The dual task gait, 10-meter walking test and a motor (carrying a full water glass) will be combined with the task and evaluated with the G-Walk portable device.
Andet: Dual tak gait assessment (motor+cognitive)
The dual task gait will be combined with a 10-meter walking test and a cognitive (1-back test) task and evaluated with the G-Walk portable device.

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
gait speed
Tidsramme: 20 minutes
Gait speed is the time one takes to walk a specified distance on level surfaces over a short distance.
20 minutes
cadence
Tidsramme: 20 minutes
Cadence is the rate at which a person walk, expressed in steps per minute. The average cadence is 100 - 115 steps/min.
20 minutes
stride length
Tidsramme: 20 minutes
Stride length is defined as the distance between successive ground contacts of the same foot.
20 minutes

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Afyonkarahisar Health Sciences University

Efterforskere

  • Ledende efterforsker: Emel TAŞVURAN HORATA, PhD, Afyonkarahisar Health Science University

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

1. marts 2021

Primær færdiggørelse (Forventet)

20. marts 2023

Studieafslutning (Forventet)

20. marts 2023

Datoer for studieregistrering

Først indsendt

2. marts 2021

Først indsendt, der opfyldte QC-kriterier

2. marts 2021

Først opslået (Faktiske)

5. marts 2021

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

5. marts 2021

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

2. marts 2021

Sidst verificeret

1. marts 2021

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Andre undersøgelses-id-numre

  • 2021/144

Plan for individuelle deltagerdata (IPD)

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Ingen

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Kliniske forsøg med Børnekræft

Kliniske forsøg med Gait assessment (single)

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Betingelser

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