Tilpasning og RCT af skriftlig eksponeringsterapi til unge
14. september 2026 opdateret af: Emily Tilstra-Ferrell, Medical University of South Carolina
Tilpasning af Skriftlig Eksponeringsterapi til Unge med Posttraumatisk Stresslidelse
Skriftlig Eksponeringsterapi (WET) er en fem-sessioners mental sundhedsterapi for posttraumatisk stresslidelse (PTSD). Forskning viser, at den virker lige så godt som længere behandlinger for PTSD blandt personer over 18 år, selvom den kræver færre sessioner end andre PTSD-terapier. Dog er WET ikke blevet tilpasset og formelt testet i individuel terapi med personer i alderen 12 til 18 år. Vores studie har til formål at se, hvordan WET kan tilpasses for at imødekomme behovene hos personer i alderen 12 til 18 år, som har oplevet traumer og i øjeblikket har PTSD-symptomer. For at tilpasse WET til denne aldersgruppe vil vi først tale med PTSD-eksperter og personer i alderen 12 til 18 år for at lære, hvilke ændringer der kunne gøre WET mere egnet til unge mennesker. Vi vil også tilbyde WET til fem personer i alderen 12 til 18 år efter manualen, som den er skrevet til personer over 18 år, for at se, hvad der skal justeres.
I den næste del af studiet vil vi rekruttere 48 unge i alderen 12 til 18 år i en pædiatrisk primærklinik, som har symptomer på PTSD, og randomisere dem til enten at modtage den tilpassede version af WET eller at modtage gulstandard-behandling for PTSD: Traumefokuseret Kognitiv Adfærdsterapi. Hvis de tildeles til at modtage tilpasset WET, vil deltagerne deltage i fem til syv ugentlige terapisessioner og fem studiebesøg (før terapi samt 6 uger, 10 uger, 20 uger og 30 uger efter starten af terapien). Hvis de tildeles til at modtage TF-CBT, vil deltagerne deltage i 12 til 16 ugentlige terapisessioner og fem studiebesøg (før terapi samt 6 uger, 10 uger, 20 uger og 30 uger efter starten af terapien). Formålet med studiebesøgene over en 30-ugers periode er at få en bedre forståelse af, hvem de er som person, og deres nuværende mentale sundhedssymptomer og diagnoser. Al terapi og studiebesøg kan gennemføres remote eller personligt, efter eget valg. Personer, der er 18 år, kan deltage uden forældremyndigheds tilladelse; personer i alderen 12 til 17 år kan kun deltage med forældremyndigheds tilladelse. Vores mål er at finde den bedste måde at give effektiv PTSD-behandling til unge mennesker på, som kan leveres i virkelige pædiatriske primærplejeindstillinger, så flere mennesker i sidste ende kan få den hjælp, de har brug for efter traumatiske oplevelser.
Studieoversigt
Status
Aktiv, ikke rekrutterende
Betingelser
Intervention / Behandling
Undersøgelsestype
Interventionel
Tilmelding (Anslået)
48
Fase
- Ikke anvendelig
Kontakter og lokationer
Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.
Studiesteder
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South Carolina
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Charleston, South Carolina, Forenede Stater, 29425
- Medical University of South Carolina National Crime Victims Research and Treatment Center
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Deltagelseskriterier
Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.
Berettigelseskriterier
Aldre berettiget til at studere
- Barn
- Voksen
Tager imod sunde frivillige
Ingen
Beskrivelse
Formål 1 (Obj. 1.1) Inklusionskriterier for unge med PTSD:
- Mellem 12 og 18 år gamle. Deltagere på 18 år, som fylder 18 efter den dato, de giver samtykke til at deltage, kan deltage, men må ikke indskrives i studiet, hvis de allerede er 19 år.
- Ledsagende samtykkende omsorgsperson (undtagelse: 18-årige kan give samtykke uden ledsagende omsorgsperson)
- Udsat for en eller flere potentielt traumatiske begivenhed(er) på NCVTRC klinikkens telefonscreening.
- Evne til at forstå engelsk.
- En score på større end eller lig med 6 på Child Trauma Screen (CTS)
- Bopæl i delstaten South Carolina.
Formål 1 (Obj. 1.1) Eksklusionskriterier for unge med PTSD:
- Aktiv psykose, bipolar lidelse eller en komorbid tilstand, der kræver et højere niveau af øjeblikkelig pleje (f.eks. anorexia nervosa, alkoholabstinens).
- Aktiv selvmordsrisiko med tanker, plan og hensigt.
- Aktiv, igangværende vold, misbrug eller andre igangværende traumatiske begivenheder, der indikerer øjeblikkelige sikkerhedsbekymringer.
- Børn i pleje, slægtpleje eller med aktive DSS-undersøgelser.
- Historie med omfattende udviklings- eller intellektuel handicap.
- Enhver anden medicinsk eller psykiatrisk tilstand, der kompromitterer deltagerens evne til sikkert at deltage.
- Manglende evne eller vilje fra omsorgsperson til at samtykke til, at den unge deltager (undtagelse: 18-årige kan give samtykke uden ledsagende omsorgsperson).
Formål 1 (Obj. 1.1) Inklusionskriterier for PTSD-behandlingsudbydere:
- Kandidatgrad eller højere i psykologi eller relateret disciplin (f.eks. socialt arbejde; rådgivning).
- Nuværende udbyder af traumefokuseret behandling til unge med PTSD i ambulant setting i mindst et år.
- Evne til at forstå engelsk.
- Samtykke til at deltage i et engangsstudiebesøg.
Formål 1 (Obj 1.1) Inklusionskriterier for børnepsykiatriske primærpleje-mental sundhedsudbydere:
- Kandidatgrad eller højere i psykologi eller relateret disciplin (f.eks. socialt arbejde; rådgivning).
- Nuværende status som mental sundhedskliniker placeret i en integreret børnepsykiatrisk primærplejesetting.
- Evne til at forstå engelsk.
- Samtykke til at deltage i et engangsstudiebesøg.
Der er ingen eksklusionskriterier for Formål 1-udbydere.
Formål 1 (Obj 1.2 teatertest) og Formål 2 (RCT) Inklusionskriterier for unge med PTSD:
- Ung mellem 12 og 18 år gamle. Deltagere på 18 år, som fylder 18 efter den dato, de giver samtykke til at deltage, kan deltage, men må ikke indskrives i studiet, hvis de allerede er 19 år.
- Ledsagende samtykkende omsorgsperson (undtagelse: 18-årige kan give samtykke uden ledsagende omsorgsperson)
- Bekræftelse af en eller flere eksponeringer for tidligere potentielt traumatiske begivenhed(er). Traumabegivenhed(er) skal have fundet sted for over en måned siden ifølge DSM-5-kriterier.
- Evne til at forstå engelsk.
- En score på større end eller lig med 21 på Child and Adolescent Trauma Screen (CATS).
- Bopæl i delstaten South Carolina.
Formål 1 (Obj 1.2 teatertest) og Formål 2 (RCT) Eksklusionskriterier for unge med PTSD:
- Aktiv psykose, bipolar lidelse eller en komorbid tilstand, der kræver et højere niveau af øjeblikkelig pleje (f.eks. anorexia nervosa, alkoholabstinens).
- Aktiv selvmordsrisiko med tanker, plan og hensigt.
- Aktiv, igangværende vold, misbrug eller andre igangværende traumatiske begivenheder, der indikerer øjeblikkelige sikkerhedsbekymringer.
- Børn i pleje, slægtpleje eller med aktive DSS-undersøgelser.
- Historie med omfattende udviklings- eller intellektuel handicap.
- Enhver anden medicinsk eller psykiatrisk tilstand, der kompromitterer deltagerens evne til sikkert at deltage.
- Manglende evne eller vilje fra omsorgsperson til at samtykke til, at den unge deltager (undtagelse: 18-årige kan give samtykke uden ledsagende omsorgsperson).
- Manglende erindring om traumabegivenhed(erne).
- Personer på psykofarmaka skal være stabiliserede på medicinen i mindst to uger før studiestartsdatoen.
Rekruttering vil ikke omfatte særlige klasser af forsøgspersoner såsom fanger, gravide kvinder eller institutionelle personer.
Studieplan
Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
- Primært formål: Behandling
- Tildeling: Randomiseret
- Interventionel model: Parallel tildeling
- Maskning: Dobbelt
Våben og indgreb
Deltagergruppe / Arm |
Intervention / Behandling |
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Eksperimentel: Eksperimentel Gruppe (Skriftlig Eksponeringsterapi)
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Written Exposure Therapy (WET) is an evidence-based treatment (EBT) for PTSD among adults that involves five 45-60 minute sessions.
WET is non-inferior to gold-standard EBTs for PTSD among adults, including Cognitive Processing Therapy and Prolonged Exposure.
Each session involves 30-minutes writing following focused prompts that include recalling details of the traumatic event as well as related cognitions and emotions.
Session one also includes providing psychoeducation about posttraumatic stress disorder and the rationale for exposure.
Between sessions, the therapist reads the writing and prepares feedback.
The intervention will be delivered during five, consecutive weekly 45-60-minute sessions to participants assigned to the experimental WET condition.
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Aktiv komparator: Sammenligningsbetingelse (Traumafokuseret Kognitiv Adfærdsterapi)
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Traumafokuseret kognitiv adfærdsterapi (TF-CBT) er den gyldne standard inden for evidensbaseret terapi for unge med PTSD og består af tre faser: sikkerhed og stabilisering, gradvis eksponering og konsolidering/integration. Sikkerheds- og stabiliseringsfasen inkluderer psykoedukation, forældrekompetencetræning og opbygning af mestringsfærdigheder.
Gradvis eksponeringsfase involverer at hjælpe den unge med at beskrive en detaljeret fortælling om de traumatiske begivenhed(er) og udarbejde en in vivo-hierarki af traumarelaterede frygtede, men objektivt sikre, stimuli, som skal mødes gradvist.
I den sidste konsoliderings-/integrationsfase finder en fælles omsorgsperson-barn-session sted, hvor barnet deler sin traumafortælling med en omsorgsperson, og unge lærer færdigheder og får viden til at forbedre fremtidig sikkerhed.
Unge, der randomiseres til TF-CBT, vil modtage 12-16 på hinanden følgende ugentlige sessioner på 60 minutter i henhold til manualen.
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Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
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Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS; Adolescents Only)
Tidsramme: Baseline through study completion, an average of 6 months.
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The Kiddie Schedule for Affective Disorders and Schizophrenia, which is a psychometrically strong tool to assess diagnoses for a wide variety of mental health conditions among adolescents, will be used to assess Posttraumatic Stress Disorder (PTSD) symptoms present and diagnostic criteria over the course of the longitudinal period.
Higher scores indicate greater likelihood of meeting diagnostic criteria for PTSD.
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Baseline through study completion, an average of 6 months.
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Child and Adolescent Trauma Screen 2.0 - Caregiver and Child Report
Tidsramme: Baseline through study completion, an average of 6 months.
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The Child and Adolescent Trauma Screen (CATS) youth and caregiver reports (ages 7-17) assess exposure to 15 different types of potentially traumatic events followed by 20-items assessing PTSD symptoms.
It is a widely used psychometrically validated tool and will be used to assess the adolescent's trauma exposure history and PTSD symptoms per self and caregiver report.
Total scores on this measure range from 0 to 60; scores of 21 or higher indicate elevated symptoms of posttraumatic stress disorder (PTSD).
Higher scores indicate greater PTSD symptom severity.
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Baseline through study completion, an average of 6 months.
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Cognitive Emotion Regulation Questionnaire-Adolescent Version
Tidsramme: Baseline through study completion, an average of 6 months.
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The Cognitive Emotion Regulation Questionnaire - Adolescent Version is a 36 item psychometrically strong measure of cognitive and emotion regulation strategies and has been used widely with trauma-exposed adolescents.
The rumination subscale of the CERQ will be used to examine changes in ruminative thinking, a proposed mechanism of WET's action to be tested in the study, over the course of treatment.
Total scores on this measure range from 36 to 180.
Several subscales are included on this measure: Self-blame, Other-blame, Rumination, Catastrophizing, Putting into perspective, Positive refocusing, Positive reappraisal, Acceptance, and Planning.
Higher scores indicate higher levels of experiencing each symptom area measured (e.g., higher scores on the self blame subscale indicate greater self-blame; higher scales on the positive re-focusing indicate greater ability to positively refocus).
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Baseline through study completion, an average of 6 months.
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Acceptability of Intervention Measure (Youth and Caregivers)
Tidsramme: 6 weeks post-baseline and through study completion, an average of 6 months.
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The Acceptability of Intervention Measure is a 4-item measure used to assess patient perceptions of new interventions, including whether they believe the new treatment is agreeable, palatable, or satisfactory on a five-point Likert scale.
This measure will be administered to adolescents and their caregivers to gauge acceptability of the experimental intervention for meeting the needs of the adolescent population.
Scores are averaged; total scores on this measure range from 1 to 5. Higher scores indicate greater acceptability of the intervention (either Written Exposure Therapy or Trauma-focused Cognitive Behavior Therapy).
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6 weeks post-baseline and through study completion, an average of 6 months.
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Feasibility of Intervention Measure (Youth and Caregivers)
Tidsramme: 6 weeks post-baseline and through study completion, an average of 6 months.
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The Feasibility of Intervention Measure is a 4-item measure to assess perceptions of whether an intervention will be able to be successfully implemented within a given agency or setting to a certain population of interest.
This measure will be administered to adolescents and caregivers to gauge perceptions of feasibility of WET for delivery with adolescents.
Scores are averaged; total scores on this measure range from 1 to 5. Higher scores indicate greater perceived feasibility of the intervention (either Written Exposure Therapy or Trauma-focused Cognitive Behavior Therapy).
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6 weeks post-baseline and through study completion, an average of 6 months.
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Intervention Appropriateness Measure (Youth and Caregivers)
Tidsramme: 6 weeks post-baseline and through study completion, an average of 6 months.
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The Intervention Appropriateness Measure is a 4-item measure to assess perceptions of whether an intervention is perceived as appropriate for addressing the needs/symptoms of a population.
This measure will be administered to adolescents and caregivers to gauge perceptions of the appropriateness of WET delivered to 12 to 18 year olds.
Scores are averaged; total scores on this measure range from 1 to 5. Higher scores indicate greater perceived feasibility of the intervention (either Written Exposure Therapy or Trauma-focused Cognitive Behavior Therapy).
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6 weeks post-baseline and through study completion, an average of 6 months.
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Semi-Structured Interview (Adolescents Only)
Tidsramme: 6 week follow up (WET condition only)
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Questions will include probes about how to enhance the intervention to elicit impressions of the un-adapted content (e.g., written prompt wording, relevance of psychoeducational content, helpfulness), areas in need of adaptation, gaps missing in the manual, and recommendations for adaptations (e.g., wording alterations, content adaptations).
Interviews will also inquire about barriers and facilitators to traditional trauma-focused treatment and whether WET meets or does not meet priorities and needs of adolescents with PTSD and their caregivers.
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6 week follow up (WET condition only)
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Sekundære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
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Revised Children's Anxiety and Depression Scale - Caregiver and Child Report
Tidsramme: Baseline through study completion, an average of 6 months.
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Revised Children's Anxiety and Depression Scale caregiver and child surveys are 25-item scales assessing for depression and anxiety symptoms among youth.
The full subscales from the RCADS-47 for social phobia and obsessive compulsive disorder symptoms will also be administered to youth.
The RCADS-25 is psychometrically strong scales for use with adolescents and caregivers and therefore will be used to assess participant self-reported symptoms of depression and anxiety.
Scores range from 0 to 75 and raw scores are converted to T scores in relation to normed data based on same aged peers.
Higher scores on this measure indicate greater levels of depression and anxiety.
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Baseline through study completion, an average of 6 months.
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The Kiddie Schedule for Affective Disorders and Schizophrenia (Select Screeners and Full Modules: Schizophrenia, Mania, Eating Disorder, Suicidal Ideation; Adolescents Only)
Tidsramme: Baseline through study completion, an average of 6 months.
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The Kiddie Schedule for Affective Disorders and Schizophrenia, which is a psychometrically strong tool to assess diagnoses for a wide variety of mental health conditions among adolescents.
Screeners and, full modules when indicated following screens, will be used to facilitate accurate screening and diagnosis of comorbidities to identify whether participants meet inclusion or exclusion criteria at baseline (i.e., active psychosis, active suicidal plan and intent, anorexia nervosa, severe substance use withdrawal symptoms, active psychosis).
This interview has several subscales that allow for a diagnostic interview to assess common psychiatric conditions among youth and does not have a standardized range of scores.
The Mania, schizophrenia, eating disorder, and suicide screeners and full modules when screeners are positive will be used.
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Baseline through study completion, an average of 6 months.
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Mental Health Statistics Improvement Program (MHSIP) Youth Survey (Caregiver and Youth Report)
Tidsramme: 6 weeks post-baseline and through study completion, an average of 6 months.
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The Mental Health Statistics Improvement Program (MHSIP) Youth Survey is a standardized tool to assess youth and caregiver's perceptions of mental health services they received including treatment satisfaction and appropriateness of the intervention to meet one's mental health needs.
It has been used among adolescent and caregiver populations and has strong psychometric properties.
Total scores on this measure range from 25 to 125.
Higher scores indicate greater satisfaction with the intervention (either Written Exposure Therapy or Trauma-focused Cognitive Behavior Therapy).
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6 weeks post-baseline and through study completion, an average of 6 months.
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Therapeutic Alliance Scale for Children (TASC) - Revised (Caregiver and Child Report)
Tidsramme: 6 weeks post-baseline and through study completion, an average of 6 months.
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The Therapeutic Alliance Scale for Children (TASC) - Revised is a 12 item measure designed to assess therapeutic alliance between therapists and patients as perceived by the patient and by their caregiver.
This will be administered during the follow up phase to assess perceptions of the therapeutic alliance.
Total scores on this measure range from 12 to 48.
Higher scores indicate greater levels of therapeutic alliance.
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6 weeks post-baseline and through study completion, an average of 6 months.
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Prolonged Grief Scale - 13 (Adolescents Only)
Tidsramme: 6 weeks post-baseline and through study completion, an average of 6 months.
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Youth who endorse traumatic loss will complete the thirteen item Prolonged Grief Scale to assess for symptoms of traumatic grief.
Total scores on this measure range from 11 to 55; scores of 30 or higher indicate elevated symptoms of prolonged grief.
Higher scores indicate higher levels of prolonged grief disorder symptoms.
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6 weeks post-baseline and through study completion, an average of 6 months.
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Rosenberg Self Esteem Scale
Tidsramme: Baseline through study completion, an average of 6 months.
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The Rosenberg Self Esteem Scale is comprised of 10 items assessing self esteem among youth.
Responses range from 0 to 30 and lower scores indicate lower levels of self esteem.
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Baseline through study completion, an average of 6 months.
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Multidimensional Scale of Perceived Social Support
Tidsramme: Baseline through study completion, an average of 6 months.
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The Multidimensional Scale of Perceived Social Support will be administered to youth and their caregivers to assess perceptions of their current social support.
This twelve item scale has a potential score range of 12 to 84; higher scores indicate higher levels of perceived social support.
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Baseline through study completion, an average of 6 months.
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Posttraumatic Stress Disorder Checklist - 8 (Caregiver Only)
Tidsramme: Baseline, 6-, 10-, 20-, 30-week follow up
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The Posttraumatic Stress Disorder (PTSD) Checklist - 8 will be used to assess caregiver symptoms of PTSD.
Total range of potential scores is from 8 to 32 and higher scores indicate greater PTSD symptomatology among caregivers.
Scores over 12 indicate likelihood of PTSD symptoms.
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Baseline, 6-, 10-, 20-, 30-week follow up
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Alabama Parenting Questionnaire (Caregivers only)
Tidsramme: Baseline through study completion, an average of 6 months.
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The Alabama Parenting Questionnaire, nine item short form, will be used to assess parenting approaches and strategies among caregivers who participate in the trial over the course of the study.
Three subscales are assessed in the measure: Positive parenting (possible score range: 6-30), inconsistent discipline (possible score range: 6-30), and poor supervision (possible score range: 9-45).
Higher scores on each subscale indicate greater levels of each of the subscale categories assessed.
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Baseline through study completion, an average of 6 months.
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Parental Self Efficacy Scale (caregivers only)
Tidsramme: Baseline through study completion, an average of 6 months.
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The Parental Self Efficacy Scale 5 item measure will be used to assess Parental Self Efficacy among caregivers who participate in the study.
Total score responses range from 5 to 25 and higher scores indicate higher levels of perceived self efficacy as a parent.
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Baseline through study completion, an average of 6 months.
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DSM-5-TR Parent/Guardian-Rated Level 1 Cross-Cutting Symptom Measure (Caregiver Report)
Tidsramme: Baseline through study completion, an average of 6 months.
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The DSM-5-TR Parent/Guardian-Rated Level 1 Cross-Cutting Symptom Measure is a 25 item measure will be used to assess caregiver perceptions of their child mental health with regard to several domains (Depression, Anger and Irritability, Mania, Anxiety, Somatic symptoms, Inattention, Suicidal ideation/attempt, Psychosis, Sleep disturbance, Repetitive thoughts and behaviors, and Substance use).
The measure will be administered to assess caregiver perceptions of these symptoms among youth as perceived by caregivers over the course of the study as well as will be used at baseline to screen for the presence of potential comorbid symptoms that could indicate a need to further assess for potential exclusion criteria
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Baseline through study completion, an average of 6 months.
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Andre resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
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Accountable Health Communities Health Related Social Needs Screening Tool - Caregiver and Child Report
Tidsramme: Baseline
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Select items from the Accountable Health Communities Health Related Social Needs Screening Tool will be used to assess for factors related to social determinants of health, such as food insecurity, housing insecurity, and other basic needs.
Questions are administered to caregivers and youth to characterize the sample and to connect families to resources, as needed.
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Baseline
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Adverse Childhood Events Scale - Youth Version
Tidsramme: Baseline
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Adolescent participants will complete the Adverse Childhood Events Scale - Youth Version at baseline to assess for a wide range of adverse childhood events that are not captured on the CATS 2.0 including emotional abuse, divorce, familial incarceration, parental substance use, and neglect.
Findings will be used to inform comprehensive trauma assessment.
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Baseline
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Measure of Adolescent Relationship Harassment and Abuse - Short Form
Tidsramme: Baseline
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Adolescent participants will complete the Measure of Adolescent Relationship Harassment and Abuse - Short Form at baseline to assess for exposure to Teen Dating Violence, some of which may not otherwise be captured on the CATS 2.0.
Findings will be used to inform comprehensive trauma assessment.
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Baseline
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HARK Intimate Partner Violence Screener (Caregiver Only)
Tidsramme: Baseline
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The HARK will be used to screen for lifetime and past year Intimate Partner Violence among caregivers in the study at baseline.
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Baseline
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Trauma History Questionnaire (Caregivers Only)
Tidsramme: Baseline
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Caregivers will complete the 24 item trauma history questionnaire to assess for trauma history among caregivers who participate in the study.
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Baseline
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Samarbejdspartnere og efterforskere
Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.
Samarbejdspartnere
Publikationer og nyttige links
Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.
Generelle publikationer
- Sloan DM, Marx BP, Lee DJ, Resick PA. A Brief Exposure-Based Treatment vs Cognitive Processing Therapy for Posttraumatic Stress Disorder: A Randomized Noninferiority Clinical Trial. JAMA Psychiatry. 2018 Mar 1;75(3):233-239. doi: 10.1001/jamapsychiatry.2017.4249.
- Sloan DM, Marx BP, Acierno R, Messina M, Muzzy W, Gallagher MW, Litwack S, Sloan C. Written Exposure Therapy vs Prolonged Exposure Therapy in the Treatment of Posttraumatic Stress Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2023 Nov 1;80(11):1093-1100. doi: 10.1001/jamapsychiatry.2023.2810.
- LoSavio ST, Worley CB, Aajmain ST, Rosen CS, Wiltsey Stirman S, Sloan DM. Effectiveness of written exposure therapy for posttraumatic stress disorder in the Department of Veterans Affairs Healthcare System. Psychol Trauma. 2023 Jul;15(5):748-756. doi: 10.1037/tra0001148. Epub 2021 Oct 28.
Datoer for undersøgelser
Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.
Studer store datoer
Studiestart (Faktiske)
6. maj 2026
Primær færdiggørelse (Anslået)
28. februar 2031
Studieafslutning (Anslået)
28. februar 2031
Datoer for studieregistrering
Først indsendt
23. marts 2026
Først indsendt, der opfyldte QC-kriterier
23. marts 2026
Først opslået (Faktiske)
27. marts 2026
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
15. september 2026
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
14. september 2026
Sidst verificeret
1. september 2026
Mere information
Begreber relateret til denne undersøgelse
Nøgleord
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- Pro00149514
Plan for individuelle deltagerdata (IPD)
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