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Effect of Adding Augmented Cues /Hand Stroke Patient (AUGMENTED CUES)

13. juni 2026 opdateret af: Mostafa Abdullah Abdelazim Ahmed, Cairo University

Effect of Adding Augmented Cues to Physical Therapy Intervention on Hand Function Post Stroke Patients

This study aims to investigate the effect of adding augmented cues to conventional physical therapy intervention on hand function in patients with post-stroke hemiparesis. Fifty patients with subacute ischemic stroke will be randomly assigned to either a study group receiving augmented cue-based training in addition to conventional physical therapy or a control group receiving conventional physical therapy alone. Hand function will be assessed before and after the intervention period using the Nine-Hole Peg Test (NHPT), hand grip strength measured by a dynamometer, and pressure pain threshold measured by a pressure algometer. The findings of this study may provide evidence regarding the effectiveness of augmented cue-based rehabilitation strategies in improving hand function after stroke.

Studieoversigt

Status

Ikke rekrutterer endnu

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

Stroke is one of the leading causes of long-term disability worldwide and frequently results in impaired hand function, reduced dexterity, decreased grip strength, and limitations in activities of daily living. Conventional physical therapy is commonly used to improve upper extremity function; however, recovery of hand performance remains challenging for many stroke survivors.

Augmented cues provide additional sensory information through visual, auditory, or sensorimotor feedback that may enhance motor learning and neuroplasticity. Incorporating augmented cues into rehabilitation programs may improve patient engagement, increase repetition of task-specific movements, and facilitate functional recovery.

The purpose of this randomized controlled trial is to examine the effectiveness of adding augmented cue-based training to conventional physical therapy intervention in improving hand function among patients with subacute ischemic stroke.

A total of 50 participants meeting the eligibility criteria will be recruited and randomly assigned into two equal groups:

Study Group: Participants will receive augmented cue-based training combined with conventional physical therapy.

Control Group: Participants will receive conventional physical therapy only.

The intervention will be conducted over an eight-week treatment period. Outcome measures will be collected before and after treatment and will include:

  1. Nine-Hole Peg Test (NHPT) to assess manual dexterity.
  2. Hand grip strength measured using a hand dynamometer.
  3. Pressure pain threshold measured using a pressure algometer.

The primary objective is to determine whether the addition of augmented cues results in greater improvement in hand function compared with conventional physical therapy alone. The results may contribute to the development of more effective rehabilitation strategies for individuals recovering from stroke.

Undersøgelsestype

Interventionel

Tilmelding (Anslået)

50

Fase

  • Ikke anvendelig

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiekontakt

Undersøgelse Kontakt Backup

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

  • Voksen

Tager imod sunde frivillige

Ingen

Beskrivelse

Inclusion Criteria:

  • - Male and female patients.
  • Age between 40 and 60 years.
  • First-ever subacute ischemic stroke.
  • Time since stroke between 6 weeks and 6 months.
  • Unilateral upper limb involvement.
  • Able to understand and follow verbal instructions.
  • Medically stable and able to participate in the rehabilitation program.
  • Willing to provide informed consent.

Exclusion Criteria:

  • - Hemorrhagic stroke.
  • Bilateral stroke involvement.
  • Severe cognitive impairment or severe aphasia interfering with participation.
  • Severe visual or auditory deficits affecting training.
  • Severe upper limb spasticity that prevents hand training.
  • Other neurological disorders affecting upper limb function.
  • Severe musculoskeletal disorders of the upper limb.
  • Participation in another rehabilitation trial during the study period.
  • Unstable cardiovascular or medical conditions.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: Behandling
  • Tildeling: Randomiseret
  • Interventionel model: Parallel tildeling
  • Maskning: Ingen (Åben etiket)

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
Aktiv komparator: control group
Participants will receive a conventional physical therapy program for hand rehabilitation after stroke. Treatment will be administered three times per week for eight weeks (24 sessions), with each session lasting 60 minutes and including range of motion exercises, strengthening exercises, stretching, and task-oriented hand training.
Andet: Conventional physical therapy
Participants will receive a conventional physical therapy program for upper limb and hand rehabilitation after stroke. The program includes stretching exercises, range of motion exercises, strengthening exercises, and task-oriented hand training. Treatment will be provided three times per week for eight weeks (24 sessions).
Eksperimentel: musical gloves
articipants will receive the same conventional physical therapy program provided to the control group in addition to MusicGlove training. Treatment will be administered three times per week for eight weeks (24 sessions). MusicGlove will provide augmented visual, auditory, and performance feedback during task-specific hand training.
Andet: Conventional physical therapy
Participants will receive a conventional physical therapy program for upper limb and hand rehabilitation after stroke. The program includes stretching exercises, range of motion exercises, strengthening exercises, and task-oriented hand training. Treatment will be provided three times per week for eight weeks (24 sessions).
Enhed: musicgloves training
MusicGlove is a sensor-based rehabilitation device that provides augmented visual, auditory, and performance feedback during task-specific hand exercises. Participants perform repetitive thumb-to-finger opposition and grasping movements synchronized with computer-based musical activities. Training will be provided in addition to conventional physical therapy three times per week for eight weeks.

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Nine-Hole peg Test (NHPT)
Tidsramme: Baseline and after 8 weeks of treatment
Manual dexterity assessed using the Nine-Hole Peg Test. The time required to place and remove nine pegs will be recorded in seconds. Lower scores indicate better hand dexterity.
Baseline and after 8 weeks of treatment

Sekundære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
hand grip strength
Tidsramme: Baseline and after 8 weeks of treatment
Hand grip strength will be assessed using a calibrated hand dynamometer. Participants will perform maximal voluntary grip contractions, and the average value of three trials will be recorded in kilograms. Higher values indicate greater hand strength.
Baseline and after 8 weeks of treatment
pressure pain threshold
Tidsramme: Baseline and after 8 weeks of treatment
Pressure pain threshold of the Extensor Carpi Radialis Brevis muscle will be measured using a digital pressure algometer. Pressure will be applied at a standardized rate until the participant first perceives pain. Higher values indicate lower pain sensitivity.
Baseline and after 8 weeks of treatment

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Cairo University

Efterforskere

  • Studiestol: Moshera H Darwish, PHD, Professor of Physical Therapy for Neurology and Neurosurgery Faculty of Physical Therapy Cairo University
  • Studieleder: mariam m elsayed, phd, Lecturer in department of physical Therapy for Neurology and Neurosurgery Faculty of physical therapy Cairo University
  • Studieleder: Essam M Abdulwahab, PHD, Professor of Neurology Faculty of Medicine Al-Azhar university

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Anslået)

1. august 2026

Primær færdiggørelse (Anslået)

1. august 2027

Studieafslutning (Anslået)

1. august 2027

Datoer for studieregistrering

Først indsendt

13. juni 2026

Først indsendt, der opfyldte QC-kriterier

13. juni 2026

Først opslået (Faktiske)

17. juni 2026

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

17. juni 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

13. juni 2026

Sidst verificeret

1. juni 2026

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

  • P.T.REC/012/006310

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

INGEN

IPD-planbeskrivelse

Individual participant data (IPD) will be available from the corresponding author upon reasonable request.

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