MRI Assessment of Leukemia Response to Therapy

Inclusion Criteria:

• Newly diagnosed or relapsed AML patients, who are scheduled to receive standard induction therapy.
• Age > 8 years and requiring no sedation.
• Patients must not be pregnant
• Women of childbearing potential must have negative serum pregnancy test performed within 7-days prior to start of study
• The subject or subject's legal guardian has the ability to understand and the willingness to sign a written informed consent and/or assent document. A signed study-specific informed consent and/or assent must be obtained prior to any study specific procedures.

Exclusion Criteria:

• Patients who would be normally excluded from undergoing an MRI examination - patients with a pacemaker, aneurysm clip or any other condition that would warrant avoidance of a strong magnetic field.
• Patients who have known or suspected allergy to gadolinium-based contrast agent.
• Severe claustrophobia precluding subject from undergoing a MRI
• Patients with acute or chronic kidney dysfunction (estimated Glomerular Filtration Rate (eGFR) < 30ml/min/1.73 m2 as calculated using the Modification of Diet in Renal Disease (MDRD) Equation)
• Pregnant women are excluded from this study because of possible risk to the fetus.