Impact of Mirror Therapy Combined With Conventional Training on Gait and Lower Limb Motor Function Among Post-Stroke Patients
Descripción general del estudio
Estado
Estado
Condiciones
Condiciones
Intervención / Tratamiento
Intervención / Tratamiento
Tipo de estudio
Tipo de estudio
Inscripción (Estimado)
Inscripción
Fase
Fase
- No aplica
Contactos y Ubicaciones
Estudio Contacto
Estudio Contacto
- Nombre: Muhammad Ammar Muhammad Ammar, DPT, MS-PT NPT
- Número de teléfono: +923138092081
- Correo electrónico: ammarkhanazxc36@gmail.com
Copia de seguridad de contactos de estudio
- Nombre: Dr Nazish Rafique, DPT, MS-PT NMPT
- Número de teléfono: +923002132436
- Correo electrónico: nazish.rafique@uipt.iiui.edu.pk
Ubicaciones de estudio
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Balochistan
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Quetta, Balochistan, Pakistán
- Reclutamiento
- Department of Physical Therapy at suleman medical complex hospital, Quetta.
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Contacto:
- Dr Nazish Rafique
- Número de teléfono: +923138092081
- Correo electrónico: ammar@gmail.com
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Criterios de participación
Criterio de elegibilidad
Criterio de elegibilidad
Edades elegibles para estudiar
- Adulto
- Adulto Mayor
Acepta Voluntarios Saludables
Descripción
Inclusion Criteria:
- Diagnosed with the first-ever unilateral stroke.
- Duration of stroke between 3 months and 6 months (subacute to chronic stage).
- Both male and female patients aged 40 to 70 years.
- Ability to walk at least 10 meters independently.
- Mini Mental State Examination (MMSE) score >24.
- Brunnstrom stage of recovery for the lower limb is > 3, indicating some voluntary movement out of synergy.
Exclusion Criteria:
- Severe cognitive impairment, perceptual deficits, or inability to follow simple verbal commands (e.g., severe aphasia or low MMSE score).
- Presence of other neurological disorders affecting motor performance such as Parkinson's disease, multiple sclerosis, traumatic brain injury, or cerebellar disorders.
- Severe musculoskeletal disorders of the lower limb, including fracture, contracture, severe osteoarthritis, or pain limiting participation in exercise.
- Uncontrolled medical conditions such as unstable hypertension, uncontrolled diabetes mellitus, a recent cardiac event, or other conditions making exercise unsafe.
- Severe visual impairment, vestibular dysfunction, or hearing loss that may interfere with treatment instructions or mirror-based feedback.
- Severe unilateral neglect (hemispatial neglect) or apraxia interfering with task performance.
- Current participation in another physiotherapy, rehabilitation, or interventional research study during the data collection period.
Plan de estudios
¿Cómo está diseñado el estudio?
Detalles de diseño
- Propósito principal: Tratamiento
- Asignación: Aleatorizado
- Modelo Intervencionista: Asignación paralela
- Enmascaramiento: Único
Número de brazos
Armas e Intervenciones
Grupo de participantes/brazoGrupo de participantes/brazo |
Intervención / TratamientoIntervención / Tratamiento |
|---|---|
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Experimental: Group A
Participants in this group will receive mirror therapy-based functional training with conventional lower limb training.
This training program will focus on gait and lower limb motor function.
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(Basic) - Sitting position:
Passive and active-assisted range of motion exercises for hip, knee, and ankle joints of the affected limb
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Comparador activo: Group B
Participants in this group will receive conventional lower limb training.
This training program will focus on gait and lower limb motor function.
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Passive and active-assisted range of motion exercises for hip, knee, and ankle joints of the affected limb
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¿Qué mide el estudio?
Medidas de resultado primarias
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
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10-Meter Walk Test (10MWT)
Periodo de tiempo: Baseline, Weeks 3 and 6.
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This test measures gait speed (m/s) over a short distance and is a highly sensitive measure of functional walking ability.
It has excellent test-retest reliability (ICC = 0.95 to 0.99) in individuals with chronic stroke and is considered a valid core outcome measure for gait recovery.
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Baseline, Weeks 3 and 6.
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Timed Up and Go Test (TUG)
Periodo de tiempo: Baseline, Weeks 3 and 6.
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This test assesses functional mobility and dynamic balance by measuring the time (in seconds) it takes an individual to stand up from a chair, walk 3 meters, turn, walk back, and sit down.
It demonstrates excellent reliability (ICC = 0.95) in the stroke population and is highly responsive to changes in mobility.
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Baseline, Weeks 3 and 6.
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Fugl-Meyer Assessment for Lower Extremity (FMA-LE)
Periodo de tiempo: Baseline, Weeks 3 and 6.
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This is a stroke-specific performance-based impairment index used to quantitatively measure motor function, sensation, and coordination in the lower limb.
It is widely regarded as the gold standard for assessing motor recovery after stroke, with high inter-rater reliability (ICC = 0.97).
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Baseline, Weeks 3 and 6.
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Wisconsin Gait Scale (WGS)
Periodo de tiempo: Baseline, Weeks 3 and 6.
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This is a valid and reliable observational gait analysis tool specifically designed for the qualitative assessment of hemiplegic gait.
It assesses 14 observable parameters across different phases of gait (e.g., stance, swing) and has high inter-rater (r = 0.91) and test-retest (r = 0.92) reliability in stroke patients (Rodriquez et al., 1996).
The WGS was selected to capture the nuanced spatiotemporal improvements in gait pattern (e.g., step length, symmetry) that are clinically meaningful but may not be fully reflected in speed or timed tests alone.
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Baseline, Weeks 3 and 6.
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Colaboradores e Investigadores
Patrocinador
Patrocinador
Publicaciones y enlaces útiles
Publicaciones Generales
- GBD 2021 Stroke Collaborators. (2023). Global, regional, and national burden of stroke and its risk factors, 1990-2021: A systematic analysis for the Global Burden of Disease Study 2021. The Lancet Neurology, 22(10), 915-939. 2. Khan, M., Ahmed, S., & Anwar, S. (2022). Burden of stroke in Pakistan: A growing concern. Journal of Pakistan Medical Association, 72(2), 242-246. 3. Li, S., Francisco, G. E., & Zhou, P. (2018). Post-stroke hemiplegic gait: New perspective and insights. Physical Medicine and Rehabilitation Clinics of North America, 29(4), 719-735. 4. Hatem, S. M., Saussez, G., Della Faille, M., Prist, V., Zhang, X., Dispa, D., et al. (2016). Rehabilitation of motor function after stroke: A multiple systematic review focused on techniques to stimulate upper extremity recovery. Frontiers in Human Neuroscience, 10, 442. 5. Garrison, K. A., Winstein, C. J., & Aziz-Zadeh, L. (2010). The mirror neuron system: A neural substrate for methods in stroke rehabilitation. Neurorehabilitation and Neural Repair, 24(5), 404-412. 6. Thieme, H., Morkisch, N., Mehrholz, J., Pohl, M., Behrens, J., & Dohle, C. (2018). Mirror therapy for improving motor function after stroke. Cochrane Database of Systematic Reviews, 7, CD008449. 7. Broderick, P., Horgan, F., Blake, C., & O'Keeffe, M. (2022). Mirror therapy for improving lower limb motor function and mobility after stroke: A systematic review and meta-analysis. Clinical Rehabilitation, 36(4), 437-453. 8. Veerbeek, J. M., van Wegen, E., van Peppen, R., van der Wees, P. J., Hendriks, E., Rietberg, M., et al. (2014). What is the evidence for physical therapy poststroke? A systematic review and meta-analysis. PLoS ONE, 9(2), e87987. 9. Hornby, T. G., Reisman, D. S., Ward, I. G., Scheets, P. L., Miller, A., Haddad, D., et al. (2020). Clinical practice guideline to improve locomotor function following chronic stroke, incomplete spinal cord injury, and brain injury. Journal of Neurologic Physical Therapy, 44(1), 49-100.
Fechas de registro del estudio
Fechas importantes del estudio
Inicio del estudio (Actual)
Inicio del estudio
Finalización primaria (Estimado)
Finalización primaria
Finalización del estudio (Estimado)
Finalización del estudio
Fechas de registro del estudio
Enviado por primera vez
Enviado por primera vez
Primero enviado que cumplió con los criterios de control de calidad
Primero enviado que cumplió con los criterios de control de calidad
Publicado por primera vez (Actual)
Publicado por primera vez
Actualizaciones de registros de estudio
Última actualización publicada (Actual)
Última actualización publicada
Última actualización enviada que cumplió con los criterios de control de calidad
Última actualización enviada que cumplió con los criterios de control de calidad
Última verificación
Última verificación
Más información
Términos relacionados con este estudio
Palabras clave
Términos MeSH relevantes adicionales
Otros números de identificación del estudio
Otros números de identificación del estudio
- IIUI/RERC/ADT/2026/05/260
Plan de datos de participantes individuales (IPD)
¿Planea compartir datos de participantes individuales (IPD)?
Información sobre medicamentos y dispositivos, documentos del estudio
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