Prediction and Management of Delayed Graft Function Based on Donor Criteria and LifePort Platform (Xi'anCri)

Inclusion Criteria:

Donor

• 1. Comply with the national donation after citizen death guideline
• 2. No high risk activities: such as history of drug abuse, history of intravenous drug use and risky sexual behavior
• 3. No malignant melanoma, metastatic cancer, or incurable cancer; some of the early stages of cancer after a successful treatment can also be considered
• 4. No activity of untreated systemic bacterial, viral or fungal infection;
• 5. Patients definitely identified

Recipient:

• 1. 65 y old ≥Age> = 18 years old, male or female
• 2. BMI<26
• 3. Renal transplantation first time
• 4. Not in pregnancy or lactation, pregnancy test was negative, and promise not to be pregnant during treatment.
• 5. Before the clinical trial, Patient sign informed consent voluntarily

Exclusion Criteria:

Donor

• 1. Older than 65 years old
• 2.Serum hepatitis B virus (HBV), hepatitis C virus (HCV), HIV positive
• 3.Donor kidney cold storage time over 30 hours
• 4.Warm ischemia time over 20 minutes
• 5.Other reagents are added perfusion for regulation of donor renal function

Recipient:

• 1.Involved in other study.
• 2.Double organ or multi-organ transplant
• 3.A,B,O blood type-incompatible