Intensive Intervention for Smokers - 6
Intensive Intervention for Smokers in Alcohol Treatment
調査の概要
詳細な説明
Introduction. The purpose of this study was to investigate the efficacy of an intensive tobacco cessation intervention for alcohol-dependent smokers in early recovery.
Methods. A total of 162 alcohol-dependent smokers were randomized to either intensive intervention for smoking cessation or usual care. The intensive intervention consisted of 16 sessions of individual cognitive behavior therapy (CBT) and combination nicotine replacement therapy that lasted 26 weeks. Usual care involved referral to a free-standing smoking cessation program that provided smoking cessation counseling of varying duration and guideline-concordant medications. The primary cessation outcome was verified 7-day point prevalence abstinence (PPA) at 12, 26, 38, and 52 weeks.
Results. At 12 and 26 weeks, the verified 7-day point-prevalence quit rate was significantly higher for the intensive intervention group than for the usual care group (both p = .03). However, the quit rates for the two treatment groups were not significantly different at 38 or 52 weeks. Verified 30-day alcohol abstinence rates were not significantly different for the two treatment groups at any of the follow-up assessments.
Conclusions. The intensive smoking cessation intervention yielded a higher short-term smoking quit rate without jeopardizing sobriety. A chronic care model might facilitate maintenance of smoking cessation during the first year of alcohol treatment and perhaps for longer periods of time. It is hoped that studies such as this will inform the development of more effective interventions for concurrent alcohol and tobacco use disorders.
研究の種類
入学 (実際)
段階
- 適用できない
連絡先と場所
研究場所
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California
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San Francisco、California、アメリカ、94121
- VA Medical Center
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-
参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
説明
Inclusion Criteria:
- at least 18 years of age
- alcohol as primary drug of abuse
- currently smoking at least 10 or more cigarettes
- abstinent from alcohol for at least 7 days and not more than 30 days
- self-reported interest in quitting smoking
Exclusion Criteria:
- any contraindications for nicotine patches or lozenges (e.g., unstable angina or recent myocardial infarction
- skin allergy to the nicotine patch
- severe cardiovascular disease
- lactation
- pregnancy by self-report or by positive serum pregnancy test in pre-menopausal women)
- unstable psychiatric disorder
- severe cognitive impairment
研究計画
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：処理
- 割り当て：ランダム化
- 介入モデル：並列代入
- マスキング：独身
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
|
実験的：Intensive intervention
Extended cognitive behavior therapy (16 sessions) plus nicotine patches and lozenges
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16 sessions of cognitive behavior therapy over 6 months
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|
他の：Usual care
Referral to the smoking cessation clinic
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Referral to smoking cessation clinic
他の名前：
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この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
7 day point prevalence of cigarette abstinence
時間枠：Assessed at 3, 6, 9, and 12 months
|
Participants are asked whether they smoked any cigarettes during the past seven days.
Expired-air carbon monoxide is measured to validate abstinence.
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Assessed at 3, 6, 9, and 12 months
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二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Alcohol use
時間枠：Assessed at 3, 6, 9, and 12 months
|
Participants were asked to report use of alcohol during the past 90 days, using a timeline follow-back interview method
|
Assessed at 3, 6, 9, and 12 months
|
協力者と研究者
捜査官
- 主任研究者：Timothy Carmody, Ph.D.、University of California, San Francisco
研究記録日
主要日程の研究
研究開始
一次修了 (実際)
研究の完了 (実際)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (見積もり)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
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