Imaging the Dopamine Systems in Bulimia Nervosa

Inclusion Criteria:

Participants with BN:

• Meets DSM-IV criteria for BN
• Sufficiently medically and psychiatrically stable to participate in research

Health Control Participants:

• No current or past psychiatric illness
• Between 80% and 120% of ideal body weight

Exclusion Criteria:

All participants:

• Current use of psychotropic medication such as anti psychotics or antidepressants
• Pregnant or breastfeeding
• history of substance abuse
• Significant medical illness
• High blood pressure (resting systolic blood pressure greater than 150mmHg and diastolic blood pressure greater that 90 mmHg)
• Current or lifetime history of schizophrenia, bipolar disorder, or other psychotic disorder as defined by DSM-IV
• Metal implants or paramagnetic objects contained within the body that may interfere with the MRI scan, as determined in consultation with a neuroradiologist and according to specified reference book guidelines
• Exposed to radiation in the workplace or has had a nuclear medicine procedure during the 1 year before study entry
• Previous adverse reaction to psycho stimulants