Ta strona została przetłumaczona automatycznie i dokładność tłumaczenia nie jest gwarantowana. Proszę odnieść się do angielska wersja za tekst źródłowy.

Expert-Validated ChatGPT Support for Arterial Blood Gas Interpretation (ABG-AI RCT)

24 września 2026 zaktualizowane przez: Semih Musa Coşkun, Izmir Katip Celebi University

Expert-Validated Generative AI Support for Arterial Blood Gas Interpretation in Early-Career Non-Specialist Physicians: A Randomized Controlled Study

This randomized controlled study evaluated whether expert-validated ChatGPT support improved arterial blood gas (ABG) interpretation performance among early-career non-specialist physicians. Participants completed a baseline assessment consisting of 11 standardized clinical scenarios covering five domains of ABG interpretation. Eligible participants who entered the reassessment phase were randomly assigned to either an AI-supported group or a control group.

One week after baseline assessment, participants completed a posttest using the same clinical scenarios. The AI-supported group received expert-validated ChatGPT responses before answering each case, whereas the control group completed the assessment without AI support.

The primary outcome was posttest total ABG interpretation accuracy across 55 scored items, compared between groups after adjustment for baseline accuracy. Secondary outcomes included changes in total accuracy, domain-specific accuracy, case-level performance, and item-level accuracy.

Przegląd badań

Status

Zakończony

Warunki

Interwencja / Leczenie

Typ studiów

Interwencyjne

Zapisy (Rzeczywisty)

161

Faza

  • Nie dotyczy

Kontakty i lokalizacje

Ta sekcja zawiera dane kontaktowe osób prowadzących badanie oraz informacje o tym, gdzie badanie jest przeprowadzane.

Lokalizacje studiów

    • Gaziantep
      • Gaziantep, Gaziantep, Turcja (Türkiye)
        • Gaziantep City Hospital

Kryteria uczestnictwa

Badacze szukają osób, które pasują do określonego opisu, zwanego kryteriami kwalifikacyjnymi. Niektóre przykłady tych kryteriów to ogólny stan zdrowia danej osoby lub wcześniejsze leczenie.

Kryteria kwalifikacji

Wiek uprawniający do nauki

  • Dziecko
  • Dorosły
  • Starszy dorosły

Akceptuje zdrowych ochotników

Tak

Płeć kwalifikująca się do nauki

Wszystko

Opis

Inclusion Criteria:

  • Fewer than five years of postgraduate clinical experience
  • Actively involved in patient care
  • Had not completed specialty training

Exclusion Criteria:

  • Residents
  • Specialists
  • Physicians not actively assessing patients
  • Incomplete, duplicate, or unmatchable pretest-posttest records

Plan studiów

Ta sekcja zawiera szczegółowe informacje na temat planu badania, w tym sposób zaprojektowania badania i jego pomiary.

Jak projektuje się badanie?

Szczegóły projektu

  • Główny cel: Inny
  • Przydział: Randomizowane
  • Model interwencyjny: Przydział równoległy
  • Maskowanie: Brak (otwarta etykieta)

Broń i interwencje

Grupa uczestników / Arm
Interwencja / Leczenie
Brak interwencji: Control group

Participants completed the 11 ABG cases without receiving any AI response, explanation, or recommendation

Eksperymentalny: AI-Supported Group

Before each of the 11 ABG cases, participants viewed the expert-validated ChatGPT response before providing their own answers.

Before each of the 11 arterial blood gas (ABG) cases, participants viewed a standardized ChatGPT response that had been independently validated against the expert reference key by three physician experts. The response addressed five scored domains and included a brief rationale. Participants then provided their own answers to each case.

Co mierzy badanie?

Podstawowe miary wyniku

Miara wyniku
Opis środka
Ramy czasowe
Posttest Total ABG Interpretation Accuracy
Ramy czasowe: One week after baseline assessment

Total accuracy across 55 scored items, comprising five scored domains for each of 11 ABG cases. Each item was scored as correct (1) or incorrect (0), and total accuracy was calculated as the number of correct responses divided by 55 × 100. The primary analysis compared posttest total accuracy between the AI-supported and control groups, adjusted for baseline total accuracy.

One week after baseline assessment

Miary wyników drugorzędnych

Miara wyniku
Opis środka
Ramy czasowe
Change in Total ABG Interpretation Accuracy From Pretest to Posttest
Ramy czasowe: From baseline to one week after baseline assessment

Change in total ABG interpretation accuracy from baseline (pretest) to the one-week posttest was assessed within each study group. Total accuracy was calculated across 55 scored items as the number of correct responses divided by 55 × 100.

From baseline to one week after baseline assessment
Between-Group Difference in Change in Total ABG Interpretation Accuracy
Ramy czasowe: From baseline to one week after baseline assessment

The change in total ABG interpretation accuracy from baseline to posttest was compared between the AI-supported and control groups. Change scores were calculated as posttest accuracy minus baseline accuracy.

From baseline to one week after baseline assessment
Change From Baseline in Primary Acid-Base Disorder Identification Accuracy on an 11-Item Assessment
Ramy czasowe: Baseline and one week after baseline assessment

Accuracy in identifying the primary acid-base disorder was calculated as the number of correct responses across 11 arterial blood gas cases divided by 11 and multiplied by 100. Each response was scored as correct (1) or incorrect (0). The outcome was the change in accuracy from baseline to posttest, calculated as posttest accuracy minus baseline accuracy and expressed in percentage points. Possible change scores ranged from -100 to +100 percentage points, with positive values indicating improved accuracy.

Baseline and one week after baseline assessment
Number of Participants by Change Category in Acute Asthma Exacerbation Case Interpretation Score
Ramy czasowe: Baseline and one week after baseline assessment

For the acute asthma exacerbation case, each participant received one point for each correct response across five predefined assessment domains, yielding a case-specific score ranging from 0 to 5. The posttest score was compared with the baseline score for the same case. Participants were classified into three mutually exclusive categories: improvement (posttest score greater than baseline score), no change (posttest score equal to baseline score), or deterioration (posttest score lower than baseline score). The number of participants in each category was recorded separately for the AI-supported and control groups.

Baseline and one week after baseline assessment
Item-Level ABG Interpretation Accuracy
Ramy czasowe: One week after baseline assessment

Item-level performance was evaluated across the 55 scored items, comprising five scored domains for each of the 11 ABG cases. The probability of a correct response for individual items was compared between the AI-supported and control groups.

One week after baseline assessment
Change From Baseline in Acid-Base Compensation Assessment Accuracy on an 11-Item Assessment
Ramy czasowe: Baseline and one week after baseline assessment

Accuracy in assessing acid-base compensation was calculated as the number of correct responses across 11 arterial blood gas cases divided by 11 and multiplied by 100. Each response was scored as correct (1) or incorrect (0). The outcome was the change in accuracy from baseline to posttest, calculated as posttest accuracy minus baseline accuracy and expressed in percentage points. Possible change scores ranged from -100 to +100 percentage points, with positive values indicating improved accuracy.

Baseline and one week after baseline assessment
Change From Baseline in Electrolyte and Anion Gap Assessment Accuracy on an 11-Item Assessment
Ramy czasowe: Baseline and one week after baseline assessment

Accuracy in assessing electrolyte and anion gap findings was calculated as the number of correct responses across 11 arterial blood gas cases divided by 11 and multiplied by 100. Each response was scored as correct (1) or incorrect (0). The outcome was the change in accuracy from baseline to posttest, calculated as posttest accuracy minus baseline accuracy and expressed in percentage points. Possible change scores ranged from -100 to +100 percentage points, with positive values indicating improved accuracy.

Baseline and one week after baseline assessment
Change From Baseline in Clinical Diagnosis Identification Accuracy on an 11-Item Assessment
Ramy czasowe: Baseline and one week after baseline assessment

Accuracy in identifying the most likely clinical diagnosis was calculated as the number of correct responses across 11 arterial blood gas cases divided by 11 and multiplied by 100. Each response was scored as correct (1) or incorrect (0). The outcome was the change in accuracy from baseline to posttest, calculated as posttest accuracy minus baseline accuracy and expressed in percentage points. Possible change scores ranged from -100 to +100 percentage points, with positive values indicating improved accuracy.

Baseline and one week after baseline assessment
Change From Baseline in Clinical Management Decision Accuracy on an 11-Item Assessment
Ramy czasowe: Baseline and one week after baseline assessment

Accuracy in selecting appropriate clinical management was calculated as the number of correct responses across 11 arterial blood gas cases divided by 11 and multiplied by 100. Each response was scored as correct (1) or incorrect (0). The outcome was the change in accuracy from baseline to posttest, calculated as posttest accuracy minus baseline accuracy and expressed in percentage points. Possible change scores ranged from -100 to +100 percentage points, with positive values indicating improved accuracy.

Baseline and one week after baseline assessment
Number of Participants by Change Category in Acute COPD Exacerbation Case Interpretation Score
Ramy czasowe: Baseline and one week after baseline assessment

For the acute COPD exacerbation case, each participant received one point for each correct response across five predefined assessment domains, yielding a case-specific score ranging from 0 to 5. The posttest score was compared with the baseline score for the same case. Participants were classified into three mutually exclusive categories: improvement (posttest score greater than baseline score), no change (posttest score equal to baseline score), or deterioration (posttest score lower than baseline score). The number of participants in each category was recorded separately for the AI-supported and control groups.

Baseline and one week after baseline assessment
Number of Participants by Change Category in Methanol Intoxication Case Interpretation Score
Ramy czasowe: Baseline and one week after baseline assessment

For the methanol intoxication case, each participant received one point for each correct response across five predefined assessment domains, yielding a case-specific score ranging from 0 to 5. The posttest score was compared with the baseline score for the same case. Participants were classified into three mutually exclusive categories: improvement (posttest score greater than baseline score), no change (posttest score equal to baseline score), or deterioration (posttest score lower than baseline score). The number of participants in each category was recorded separately for the AI-supported and control groups.

Baseline and one week after baseline assessment
Number of Participants by Change Category in Diabetic Ketoacidosis Case Interpretation Score
Ramy czasowe: Baseline and one week after baseline assessment

For the diabetic ketoacidosis case, each participant received one point for each correct response across five predefined assessment domains, yielding a case-specific score ranging from 0 to 5. The posttest score was compared with the baseline score for the same case. Participants were classified into three mutually exclusive categories: improvement (posttest score greater than baseline score), no change (posttest score equal to baseline score), or deterioration (posttest score lower than baseline score). The number of participants in each category was recorded separately for the AI-supported and control groups.

Baseline and one week after baseline assessment
Number of Participants by Change Category in Carbon Monoxide Intoxication Case Interpretation Score
Ramy czasowe: Baseline and one week after baseline assessment

For the carbon monoxide intoxication case, each participant received one point for each correct response across five predefined assessment domains, yielding a case-specific score ranging from 0 to 5. The posttest score was compared with the baseline score for the same case. Participants were classified into three mutually exclusive categories: improvement (posttest score greater than baseline score), no change (posttest score equal to baseline score), or deterioration (posttest score lower than baseline score). The number of participants in each category was recorded separately for the AI-supported and control groups.

Baseline and one week after baseline assessment
Number of Participants by Change Category in Acute Kidney Injury on Chronic Kidney Disease With Hyperkalemia Case Interpretation Score
Ramy czasowe: Baseline and one week after baseline assessment

For the acute kidney injury on chronic kidney disease with hyperkalemia case, each participant received one point for each correct response across five predefined assessment domains, yielding a case-specific score ranging from 0 to 5. The posttest score was compared with the baseline score for the same case. Participants were classified into three mutually exclusive categories: improvement (posttest score greater than baseline score), no change (posttest score equal to baseline score), or deterioration (posttest score lower than baseline score). The number of participants in each category was recorded separately for the AI-supported and control groups.

Baseline and one week after baseline assessment
Number of Participants by Change Category in Pulmonary Embolism Case Interpretation Score
Ramy czasowe: Baseline and one week after baseline assessment

For the pulmonary embolism case, each participant received one point for each correct response across five predefined assessment domains, yielding a case-specific score ranging from 0 to 5. The posttest score was compared with the baseline score for the same case. Participants were classified into three mutually exclusive categories: improvement (posttest score greater than baseline score), no change (posttest score equal to baseline score), or deterioration (posttest score lower than baseline score). The number of participants in each category was recorded separately for the AI-supported and control groups.

Baseline and one week after baseline assessment
Number of Participants by Change Category in Panic Attack With Hyperventilation Case Interpretation Score
Ramy czasowe: Baseline and one week after baseline assessment

For the panic attack with hyperventilation case, each participant received one point for each correct response across five predefined assessment domains, yielding a case-specific score ranging from 0 to 5. The posttest score was compared with the baseline score for the same case. Participants were classified into three mutually exclusive categories: improvement (posttest score greater than baseline score), no change (posttest score equal to baseline score), or deterioration (posttest score lower than baseline score). The number of participants in each category was recorded separately for the AI-supported and control groups.

Baseline and one week after baseline assessment
Number of Participants by Change Category in Diuretic-Associated Metabolic Alkalosis Case Interpretation Score
Ramy czasowe: Baseline and one week after baseline assessment

For the diuretic-associated metabolic alkalosis case, each participant received one point for each correct response across five predefined assessment domains, yielding a case-specific score ranging from 0 to 5. The posttest score was compared with the baseline score for the same case. Participants were classified into three mutually exclusive categories: improvement (posttest score greater than baseline score), no change (posttest score equal to baseline score), or deterioration (posttest score lower than baseline score). The number of participants in each category was recorded separately for the AI-supported and control groups.

Baseline and one week after baseline assessment
Number of Participants by Change Category in Hypoglycemia Case Interpretation Score
Ramy czasowe: Baseline and one week after baseline assessment

For the hypoglycemia case, each participant received one point for each correct response across five predefined assessment domains, yielding a case-specific score ranging from 0 to 5. The posttest score was compared with the baseline score for the same case. Participants were classified into three mutually exclusive categories: improvement (posttest score greater than baseline score), no change (posttest score equal to baseline score), or deterioration (posttest score lower than baseline score). The number of participants in each category was recorded separately for the AI-supported and control groups.

Baseline and one week after baseline assessment
Number of Participants by Change Category in Upper Gastrointestinal Bleeding With Hypovolemic Shock Case Interpretation Score
Ramy czasowe: Baseline and one week after baseline assessment

For the upper gastrointestinal bleeding with hypovolemic shock case, each participant received one point for each correct response across five predefined assessment domains, yielding a case-specific score ranging from 0 to 5. The posttest score was compared with the baseline score for the same case. Participants were classified into three mutually exclusive categories: improvement (posttest score greater than baseline score), no change (posttest score equal to baseline score), or deterioration (posttest score lower than baseline score). The number of participants in each category was recorded separately for the AI-supported and control groups.

Baseline and one week after baseline assessment

Współpracownicy i badacze

Tutaj znajdziesz osoby i organizacje zaangażowane w to badanie.

Sponsor

Śledczy

  • Główny śledczy: Coşkun, MD, Gaziantep City Hospital

Daty zapisu na studia

Daty te śledzą postęp w przesyłaniu rekordów badań i podsumowań wyników do ClinicalTrials.gov. Zapisy badań i zgłoszone wyniki są przeglądane przez National Library of Medicine (NLM), aby upewnić się, że spełniają określone standardy kontroli jakości, zanim zostaną opublikowane na publicznej stronie internetowej.

Główne daty studiów

Rozpoczęcie studiów (Rzeczywisty)

20 maja 2026

Zakończenie podstawowe (Rzeczywisty)

5 czerwca 2026

Ukończenie studiów (Rzeczywisty)

5 czerwca 2026

Daty rejestracji na studia

Pierwszy przesłany

18 września 2026

Pierwszy przesłany, który spełnia kryteria kontroli jakości

24 września 2026

Pierwszy wysłany (Rzeczywisty)

30 września 2026

Aktualizacje rekordów badań

Ostatnia wysłana aktualizacja (Rzeczywisty)

30 września 2026

Ostatnia przesłana aktualizacja, która spełniała kryteria kontroli jakości

24 września 2026

Ostatnia weryfikacja

1 września 2026

Więcej informacji

Terminy związane z tym badaniem

Inne numery identyfikacyjne badania

  • 0449

Informacje o lekach i urządzeniach, dokumenty badawcze

Bada produkt leczniczy regulowany przez amerykańską FDA

Nie

Bada produkt urządzenia regulowany przez amerykańską FDA

Nie

Te informacje zostały pobrane bezpośrednio ze strony internetowej clinicaltrials.gov bez żadnych zmian. Jeśli chcesz zmienić, usunąć lub zaktualizować dane swojego badania, skontaktuj się z register@clinicaltrials.gov. Gdy tylko zmiana zostanie wprowadzona na stronie clinicaltrials.gov, zostanie ona automatycznie zaktualizowana również na naszej stronie internetowej .