Accumbofrontal Tract Study in 2 Populations of Patients With Anorexia Nervosa and Obsessional Compulsive Disorder and Healthy Volunteer (ACCUMBENS)

Inclusion Criteria:

• Female patients
• Age between 18 and 65 years
• Subjects free to give their written consent

For anorexia nervosa :

• Patients meeting the diagnostic criteria for anorexia nervosa according to DSM5 (American Psychiatric Association): low weight (<85% of expected weight for age and height), fear of gaining weight or becoming fat, distortion of body image, and amenorrhea for more than 3 months
• Treatment with at least one antidepressant and one anxiolytic

For OCD :

• Patients meeting the diagnostic criteria of OCDs according to DSM5 (American Psychiatric Association) : presence of obsessions and / or compulsions, resulting in clinically significant suffering (loss of at least one hour per day) or impairment at the social, occupational level or in another important area of life. These symptoms are not due to the physiological effects of a substance or a general medical condition and cannot be better explained by the symptoms of another psychiatric disorder.
• Patients with homogeneous OCD in obsession and compulsion.
• Normal weight compared to expected weight for age and height
• Treatment with at least one antidepressant and one anxiolytic

ForHealthy volunteer

•Normal weight compared to expected weight for age and height

Exclusion Criteria:

• Male
• Age <18 years or> 65 years
• Pregnancy
• Absence of free and informed consent signature
• Current processing by rTMS
• Somatic intercurrent pathologies: neurological, cardiological, pneumological, renal, hepatic, endocrine, metabolic disorders ...
• Mental retardation (WAIS-IV QI <70)
• Primary Amenorrhea
• Absolute contraindication or relative to the realization of a magnetic resonance imaging without injection of contrast medium
• Old or intercurrent psychotic pathology