Efficacy of Nasojejunal Enteral Feeding in Critically Ill Patients.
The purpose of this study is to determine if naso-jejunal feeding (feeding beyond the stomach) improves the efficacy of enteral feeding (feeding into the gut) in critically ill patients.
The study hypothesis is that in patients who fail to establish enteral feeding via the nasogastric route, introduction of nasojejunal feeding will lead to more effective enteral feeding than the current regime involving staged introduction of promotility agents.
研究概览
详细说明
The study examines the area of enteral feeding in critically ill patients. Current standard enteral feeding practice is via a nasogastric with the addition of promotility agents for patients who fail to absorb their enteral nutrition.
This study compares the efficacy of nasojejunal feeding feeding with nasogastric enteral feeding with the addition of promotility agents.
The duration of feeding will be determined by the patients nutritional requirements and their general condition. However the data will be collected for duration of enteral feeding, 28 days or ICU discharge whichever occurs first.
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
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Victoria
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Parkville、Victoria、澳大利亚、3050
- Intensive Care Unit, Royal Melbourne Hospital, Grattan Street
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Adult patients (18years or over) admitted to the ICU with an expected stay of more than 48 hours.
- Patients commenced on enteral feeding via a nasogastric tube who fail to tolerate gastric feeding due to excessive gastric aspirate volumes.
Patients who consent or if the patient is incompetent, the next of kin, who consent, to inclusion in the study.
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Exclusion Criteria:
- patients less than 18 years of age.
- Patients with known allergy to promotility agents, metoclopramide or erythromycin.
- Patients with a contra indication to nasojejunal feeding. -
学习计划
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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无干预：Standard Care
Patients will receive enteral nutrition via a nasogastric tube as per standard feeding regime
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有源比较器：Nasojejunal Arm
Patient will receive feeding via a nasojejunal feeding tube
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研究衡量的是什么？
主要结果指标
结果测量 |
大体时间 |
|---|---|
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Efficacy of feeding
大体时间：participants will be followed until death, discharge from ICU, commencement of oral or parental nutrition or 28 days post ICU admission
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participants will be followed until death, discharge from ICU, commencement of oral or parental nutrition or 28 days post ICU admission
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次要结果测量
结果测量 |
大体时间 |
|---|---|
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1. To determine the incidence of complications with enteral feeding via nasogastric and nasojejunal routes.
大体时间：participants will be followed until death, discharge from ICU, commencement of parental or oral nutrition or 28 days post ICU admission.
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participants will be followed until death, discharge from ICU, commencement of parental or oral nutrition or 28 days post ICU admission.
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2. To assess the efficacy of current strategies for optimising enteral feeding efficacy.
大体时间：participants will be followed until death, discharge from ICU commencement of oral or parental nutrition,or 28 days post ICU admission.
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participants will be followed until death, discharge from ICU commencement of oral or parental nutrition,or 28 days post ICU admission.
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合作者和调查者
调查人员
- 首席研究员：Megan Robertson、Intensive Care Unit, Royal Melbourne Hospital
研究记录日期
研究主要日期
学习开始
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.