Molecular Epidemiology of Lymphoma Patients
Primary Objectives:
- To enroll and obtain, through questionnaires, risk factor information on all study participants to develop detailed demographic, epidemiologic and behavioral profiles.
- To assess the influence of relevant epidemiologic covariates such as age, gender, smoking and family history of cancer on the panel of susceptibility biomarkers.
- To evaluate the role of genomic instability in development of lymphomas.
研究概览
详细说明
This study will include individuals diagnosed with lymphoma and individuals with no history of cancer. Half of the participants in this study will have lymphoma, and half will have no history of cancer. Information from both groups will be compared to help researchers try to learn which factors may lead to the development of lymphoma.
If you agree to take part in this study, you will be asked to complete a questionnaire at M. D. Anderson. In this questionnaire, you will be asked about your demographics (such as your age, sex, etc.), certain environmental exposures (such as pollution), your medical history, family history, diet, and your past and present smoking and alcohol use habits. This questionnaire should take about 50 minutes to complete.
You will also have about 2 ½ tablespoons of blood drawn for special tests. These tests will look for any biologic factors (such as changes in your DNA) that may be linked to lymphoma. You will not be informed of the results of any of the testing done with your blood samples.
Your participation will be over in this study once your blood has been drawn.
This is an investigational study. Up to 800 participants will take part in this study. All will be enrolled at M. D. Anderson.
研究类型
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Cases only: Newly diagnosed, previously untreated patients with lymphoma as the primary cancer.
- Age 18 years and older.
- Willing to donate 30ml of blood.
- Willing to complete a self-administered questionnaire.
- Controls only: No prior cancer.
Exclusion Criteria:
- Cases only: Prior history of cancer other than lymphoma.
- Unable to speak or read English
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
|
Cases
Participants of study with newly diagnosed lymphoma.
|
Questions about cancer risk factors, medical history, and family history of cancer.
其他名称：
|
|
Control
Participants of study from matched control group.
|
Questions about cancer risk factors, medical history, and family history of cancer.
其他名称：
|
研究衡量的是什么？
主要结果指标
结果测量 |
大体时间 |
|---|---|
|
To identify biologic (such as genes) and lifestyle factors that may increase a person's risk of developing lymphoma.
大体时间：4 Years
|
4 Years
|
合作者和调查者
调查人员
- 首席研究员：Randa El-Zein, MD, PhD、M.D. Anderson Cancer Center
出版物和有用的链接
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.