Personalised Outcomes in Children With Recurrent Wheeze
Validation of a Patient-reported Outcome Measurement Tool
This project aims to develop a PROM for preschool children with recurrent wheeze. Nearly one third of children will have at least one episode of wheeze in the first five years of life. The majority of these children grow out of the condition in early school years. However, their families go through challenging times often with numerous emergency department admissions and hospitalizations. Hospital admission rates for preschool children with wheeze attacks remain high and are increasing in the UK. New treatments have become available, but although current treatments speed recovery from a wheeze attack, still many children visit hospitals for rescue medications and medical reviews. Recent Australian data show that one fourth of these children remain at emergency departments for a less than four hours period, suggesting that with better information and education, these children could have remained at home.
Justification-Significance of the work By understanding what really matters for these families, clinicians and stakeholders will be better able to design interventions that will reduce the hospital attendances and admissions by empowering parents to manage their children's condition. More specifically, this tool will assist GPs identify which of these children need to be reviewed by specialists, aid holistic management, ensure interventions are meaningful for families and assess the benefits of novel treatments.
Methodology The items of the questionnaire have been generated through discussions with families in a qualitative research study conducted by the research team. These items will be refined and the questionnaire will be tested with families in different healthcare settings. Researchers will assess how well this questionnaire is identifying the children who present with greater number of hospital admissions and will be benefited from suggested interventions. The data will be analysed and based on the results, amendments will be made to the questionnaire, which can will then be introduced in the routine management of these children.
研究概览
详细说明
The validation of the tool will take place at St Mary's Hospital.
The questionnaire aims to measure
- incidence of wheeze attacks and use of rescue medications
- parental/caregiver perception of recurrent wheeze control
- parental/caregiver perception of effect of recurrent wheeze on family/child quality of life
Participants will be given the questionnaire at the emergency departments or outpatients clinics following having consented to the study and will be asked to fill in the questionnaire and return it to their clinician.
研究类型
注册 (预期的)
联系人和位置
学习联系方式
- 姓名:Heidi Makrinioti
- 电话号码:07771348633
- 邮箱:heidimakrinioti@gmail.com
学习地点
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London、英国、W2 1NY
- 招聘中
- St Mary's Hospital
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接触:
- ChaidoNiki Makrynioti, PhD
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
In this study caregivers of preschool children presenting with the second or more episode of wheeze that requires physician review with or without treatment (as per BTS definition of wheeze attack in preschool years) will be included.
Exclusion Criteria:
This study will exclude caregivers who do not consent to complete the questionnaire and therefore participate in the study.
This study will exclude caregivers of preschool children who present with their first episode of wheeze.
This study will exclude caregivers of preschool children who present with respiratory distress of any other etiology (foreign body inhalation, croup, lower respiratory tract infection, bronchiectasis, exacerbation of cystic fibrosis or ciliopathy)
学习计划
研究是如何设计的?
设计细节
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
feasibility of preschool wheeze assessment tool
大体时间:March 2019 - March 2020
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how easily the questionnaire can be completed
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March 2019 - March 2020
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content validity of the questionnaire
大体时间:March 2019-March 2020
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assessing validity of each item of the questionnaire as comparing with item of already existing questionnaire
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March 2019-March 2020
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
---|---|---|
reduction of avoidable emergency department admissions
大体时间:March 2020-March 2021
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effect of the tool on number of avoidable emergency department presentations
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March 2020-March 2021
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合作者和调查者
调查人员
- 首席研究员:Mando Watson、Imperial College Healthcare NHS Trust
出版物和有用的链接
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)?
IPD 计划说明
药物和器械信息、研究文件
研究美国 FDA 监管的药品
研究美国 FDA 监管的设备产品
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