LODS 在预测 ICU 30 天死亡率结果中的作用
后勤器官功能障碍系统在预测重症监护病房 30 天死亡率结果中的作用。 Cipto Mangunkusumo 综合医院患者
研究概览
研究类型
注册 (实际的)
联系人和位置
学习地点
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DKI Jakarta
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Jakarta Pusat、DKI Jakarta、印度尼西亚、10430
- Rumah Sakit Cipto Mangunkusumo
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
纳入标准:
- 入住 ICU 的成年患者(18 岁及以上)
排除标准:
- 因烧伤、冠状动脉疾病、心脏手术后入住 ICU 的患者
- LODS评分所需信息不完整的患者
- 入院后 24 小时内死亡或出院的患者
学习计划
研究是如何设计的?
设计细节
- 观测模型:队列
- 时间观点:追溯
队列和干预
团体/队列 |
干预/治疗 |
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死亡率结果
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逻辑器官功能障碍系统评分的变量,包括:GCS;心率;收缩压;血尿素;血清肌酐;尿量;白细胞计数;血小板计数; PaO2/FiO2;血清胆红素;凝血酶原时间。
其他名称:
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
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LODS评分判别能力
大体时间:入院后30天
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LODS 评分能力根据后勤器官功能障碍系统评分变量区分患者结果:GCS;心率;收缩压;血尿素;血清肌酐;尿量;白细胞计数;血小板计数; PaO2/FiO2;血清胆红素;凝血酶原时间。
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入院后30天
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LODS分数校准
大体时间:入院后30天
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LODS 评分能力基于逻辑器官功能障碍系统评分的变量预测患者结果:GCS;心率;收缩压;血尿素;血清肌酐;尿量;白细胞计数;血小板计数; PaO2/FiO2;血清胆红素;凝血酶原时间。
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入院后30天
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LODS 评分变量与患者结果之间的相关性
大体时间:入院后30天
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患者结果与每个 LODS 评分变量之间的相关性:GCS;心率;收缩压;血尿素;血清肌酐;尿量;白细胞计数;血小板计数; PaO2/FiO2;血清胆红素;凝血酶原时间。
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入院后30天
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
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患者结果
大体时间:入院后30天
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进入重症监护病房 (ICU) 后 30 天内的患者结局:死亡或存活
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入院后30天
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LODS 神经变量评分:格拉斯哥昏迷量表 (GCS)
大体时间:第一天
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GCS 变量截止分数: 14-15 0 分; 9-13 得 1 分; 6-8得3分; 3-5 得 5 分。 |
第一天
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LODS 心血管变量评分:心率 (HR) 和/或收缩压 (SBP)
大体时间:第一天
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HR(以 bpm 为单位)和/或 SBP(以 mmHg 为单位)可变截止值的分数: HR 30-139 和 SBP 90-239 为 0 分; SBP 70-89 或 240-269 或 HR >=140 得 1 分; SBP 40-69 或 >=270 得 3 分; HR <30 或 SBP <40 得 5 分。 |
第一天
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LODS 肾脏变量评分:血清尿素氮 (BUN) 和/或肌酐和/或尿量 (UO)
大体时间:第一天
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BUN(以 mg/dL 为单位)和/或肌酐(以 mg/dL 为单位)和/或 UO(以升/天为单位)可变截止值的分数: BUN <17 AND 肌酐 <1.20 AND UO 0.75-9.99 得 0 分; BUN 17-<28 或肌酐 1.20-1.59 得 1 分; BUN 28-<56 AND 肌酐 <1.60 AND UO 0.5-0.74 或 >=10 得 3 分; BUN >=56 或 UO 0.5 得 5 分。 |
第一天
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LODS 肺变量评分:机械通气 (MV) 或持续气道正压通气 (CPAP) 时的氧分压 (PaO2)/吸入氧分率 (FiO2)
大体时间:第一天
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PaO2/FiO2 分数(以 mmHg/% 为单位)可变截止值: 0 分表示没有通气和没有 CPAP; >=150 得 1 分; <150 得 3 分。 |
第一天
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LODS 血液学变量评分:白细胞 (WBC) 计数和/或血小板计数
大体时间:第一天
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WBC 分数(x10^3/L)和/或血小板计数(x10^3/L)可变截止值: WBC 2.5-49.9 和血小板 >=50 为 0 分; WBC 1.0-2.4 或 >=50.0 得 1 分 或血小板<50; WBC <1.0 得 3 分 |
第一天
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LODS 肝功能变量评分:血清胆红素和/或凝血酶原时间 (PT)
大体时间:第一天
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血清胆红素(以 mg/dL 为单位)和/或 PT(以标准的 % 为单位)变量截断值: 胆红素 <2.0 和 PT >=25 为 0 分; 胆红素 >=2.0 或 PT<25% 或 >3 得 1 分。 |
第一天
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合作者和调查者
出版物和有用的链接
一般刊物
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初级完成 (实际的)
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首次提交
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