Non-exercise Physical Activity Intervention (STAND)
2020年5月27日 更新者：Science and Research Centre Koper
Effects of Dynamic Standing vs. Static Standing on Subjective Fatigue Symptoms
Physical inactivity is prevalent in older adults and poses a risk factor for the development of type 2 diabetes.
The aim of this pilot study was to examine the effect of non-exercise physical activity using a standing desk on clinical variables in older adults with type 2 diabetes.
研究概览
研究类型
介入性
注册 (预期的)
120
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习联系方式
- 姓名：Nicolaas Bohnen, MD, PhD
- 邮箱：nbohnen@med.umich.edu
学习地点
-
-
Michigan
-
Ann Arbor、Michigan、美国、48104
- 招聘中
- University of Michigan
-
接触：
- Martijn Muller, PhD
- 电话号码：734-998-8400
- 邮箱：mtmuller@umich.edu
-
接触：
- Nico Bohnen, MD, PhD
- 电话号码：+1734-998-8400
- 邮箱：nbohnen@umich.edu
-
-
参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
65年 至 80年 (年长者)
接受健康志愿者
不
有资格学习的性别
全部
描述
Inclusion Criteria:
- older participants (65+ years) with clinically confirmed type 2 diabetes
- Body mass index above 25 and less than 40 kg/m2
Exclusion Criteria:
- participants unable to perform a short clinical and motor function test battery (sABC test, Mini-BEST)
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：随机化
- 介入模型：交叉作业
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
有源比较器：Sitting
Three hours of sitting condition with ad-libitum breaks for toilet use and stretching.
During this condition all cognitive, motor and pain scales were monitored.
|
We proposed a dynamic standing approach (working while standing accompanied by small periodic stepping movements) as a more tolerable and thereby more applicative lifestyle modification.
To evaluate this form on healthy subjects, three different conditions were applied: 3 hours of sitting, static standing and dynamic standing.
Both standing conditions were done with height-adjustable table which was developed at the University of Michigan (Ann Arbor, Michigan, USA)
其他名称：
|
|
有源比较器：Static standing
Four hours of static standing condition with ad-libitum breaks for toilet use and stretching.
During this condition all cognitive, motor and pain scales were monitored.
|
We proposed a dynamic standing approach (working while standing accompanied by small periodic stepping movements) as a more tolerable and thereby more applicative lifestyle modification.
To evaluate this form on healthy subjects, three different conditions were applied: 3 hours of sitting, static standing and dynamic standing.
Both standing conditions were done with height-adjustable table which was developed at the University of Michigan (Ann Arbor, Michigan, USA)
其他名称：
|
|
有源比较器：Dynamic standing
Four hours of dynamic standing condition with ad-libitum breaks for toilet use and stretching.
During this condition all cognitive, motor and pain scales were monitored.
|
We proposed a dynamic standing approach (working while standing accompanied by small periodic stepping movements) as a more tolerable and thereby more applicative lifestyle modification.
To evaluate this form on healthy subjects, three different conditions were applied: 3 hours of sitting, static standing and dynamic standing.
Both standing conditions were done with height-adjustable table which was developed at the University of Michigan (Ann Arbor, Michigan, USA)
其他名称：
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Oxygen consumption
大体时间：change in oxygen consumption between all three conditions, which will be measured with a minimum washout period of 3 days
|
Oxygen uptake VO2 (ml/min/kg)
|
change in oxygen consumption between all three conditions, which will be measured with a minimum washout period of 3 days
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Executive control
大体时间：change in executive control and cognitive switching levels between all three conditions, which will be measured with a minimum washout period of 3 days
|
Executive functions measured with Trail Making Test (seconds)
|
change in executive control and cognitive switching levels between all three conditions, which will be measured with a minimum washout period of 3 days
|
|
Attention levels
大体时间：change in attentional levels between all three conditions, which will be measured with a minimum washout period of 3 days
|
Measuring attention with Stroop test (seconds)
|
change in attentional levels between all three conditions, which will be measured with a minimum washout period of 3 days
|
合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
一般刊物
- Dempsey PC, Larsen RN, Sethi P, Sacre JW, Straznicky NE, Cohen ND, Cerin E, Lambert GW, Owen N, Kingwell BA, Dunstan DW. Benefits for Type 2 Diabetes of Interrupting Prolonged Sitting With Brief Bouts of Light Walking or Simple Resistance Activities. Diabetes Care. 2016 Jun;39(6):964-72. doi: 10.2337/dc15-2336. Epub 2016 Apr 13.
- Wheeler MJ, Green DJ, Ellis KA, Cerin E, Heinonen I, Naylor LH, Larsen R, Wennberg P, Boraxbekk CJ, Lewis J, Eikelis N, Lautenschlager NT, Kingwell BA, Lambert G, Owen N, Dunstan DW. Distinct effects of acute exercise and breaks in sitting on working memory and executive function in older adults: a three-arm, randomised cross-over trial to evaluate the effects of exercise with and without breaks in sitting on cognition. Br J Sports Med. 2020 Jul;54(13):776-781. doi: 10.1136/bjsports-2018-100168. Epub 2019 Apr 29.
- Sui W, Smith ST, Fagan MJ, Rollo S, Prapavessis H. The effects of sedentary behaviour interventions on work-related productivity and performance outcomes in real and simulated office work: A systematic review. Appl Ergon. 2019 Feb;75:27-73. doi: 10.1016/j.apergo.2018.09.002. Epub 2018 Sep 18.
- Marusic U, Muller MLTM, Alexander NB, Bohnen NI. Feasibility and behavioral effects of prolonged static and dynamic standing as compared to sitting in older adults with type 2 diabetes mellitus. BMC Geriatr. 2020 Jun 11;20(1):204. doi: 10.1186/s12877-020-01600-0.
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2012年1月8日
初级完成 (预期的)
2022年1月8日
研究完成 (预期的)
2022年1月8日
研究注册日期
首次提交
2020年5月23日
首先提交符合 QC 标准的
2020年5月27日
首次发布 (实际的)
2020年6月1日
研究记录更新
最后更新发布 (实际的)
2020年6月1日
上次提交的符合 QC 标准的更新
2020年5月27日
最后验证
2020年5月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.