全身振动对腹部腹部肥胖的老年人健康结果的有效性
全身振动训练在改善大脑活动,骨骼矿物质密度,生活质量和生物标志物中的有效性
这项研究的重点是全身振动训练(WBVT),这是一种使用机械振动的神经肌肉训练的形式。 WBVT已被证明可以改善肌肉功能,骨矿物质密度和生活质量。 尽管在老年人群中观察到了一些好处,但仍存在有关其在腹部腹部肥胖的老年人中有效性的研究差距。 因此,这项研究的结果将为针对该特定组的健康干预措施提供新的证据。
这项研究针对年龄在65岁及以上的门诊患者,他们符合腹肥胖的标准。 它旨在评估WBVT对脑活动,骨质疏松症,生活质量和生物学标志物的影响。 研究期为2025年2月1日至2027年1月31日,计划的样本量为120名参与者,分为一个实验组和对照组(每个参与者)。
研究概览
详细说明
这项研究的目的是调查全身振动训练对以下领域的腹部腹部肥胖症老年人的影响:
大脑活动:脑衍生的神经营养因子(BDNF)的血清水平的变化。
骨矿物质密度:使用双能X射线吸收法(DXA)测量。
生活质量:通过问卷调查评估,涵盖身体健康,心理健康和社会功能的改善。
生物标志物:总胆固醇,高密度脂蛋白胆固醇,C反应蛋白(CRP)和糖化血红蛋白(HBA1C)的水平变化。
研究类型
注册 (估计的)
阶段
- 不适用
联系人和位置
学习联系方式
- 姓名:SHIH CHUN LIN
- 电话号码:3112 +88652648000
- 邮箱:t780927t@yahoo.com.tw
参与标准
资格标准
适合学习的年龄
- 年长者
接受健康志愿者
描述
纳入标准:
门诊患者65岁或以上
被诊断为腹肥胖症
能够理解并遵循简单的说明
能够清晰地交流并表达自己的意志
愿意签署知情同意书
排除标准:
无法用普通话或台湾交流,导致无法参加研究活动
严重的视觉或听力障碍阻碍研究参与
认知障碍,肌肉骨骼或严重骨质疏松症的存在
拒绝签署知情同意书
学习计划
研究是如何设计的?
设计细节
- 主要用途:预防
- 分配:随机化
- 介入模型:并行分配
- 屏蔽:无(打开标签)
武器和干预
参与者组/臂 |
干预/治疗 |
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实验性的:全身振动训练组
实验组的参与者每周接受三次训练全身振动(WBV),总持续时间为24周。
在每次会议期间,参与者赤脚站在振动平台上,保持静态下蹲位置,膝盖在30度和脚相距30度弯曲。
在24周期间,训练方案逐渐增加,持续时间,集合数量和总运动时间从最初的10分钟到30分钟。
振动频率从20 Hz逐渐升高到40 Hz,恒定幅度为2 mm。
每个10分钟的会话包括1分钟的休息间隔。
此外,作为健康教育指南的一部分,还向所有参与者提供了由卫生与福利部卫生促进管理局颁发的“卫生措施”手册。
在24周干预计划之后,在第18和25周进行了干预后数据收集。
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全身振动训练和健康教育手册
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安慰剂比较:对照组
对照组收到了台湾卫生和福利部卫生促进管理局发行的“卫生措施”手册,并在24周内参加了30分钟的健康教育课程。
教育内容包括与运动相关的信息,对腹部肥胖(DAO)的介绍,相关的危险因素和潜在的健康后果。
在24周干预计划之后,在第18和25周进行了干预后数据收集。
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健康教育手册
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
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血液检查
大体时间:24周
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总胆固醇(TC)时间范围:基线,3个月,6个月;描述:血清总胆固醇水平以mg/dl测量。 参考值:<200 mg/dl。 甘油三酸酯(TG)时间框架:基线,3个月,6个月;描述:以mg/dl测量的血清甘油三酸酯水平。 参考值:<150 mg/dl。 低密度脂蛋白胆固醇(LDL-C)时间范围:基线,3个月,6个月;描述:以mg/dl测量的血清LDL胆固醇。 参考值:<130 mg/dl。 高密度脂蛋白胆固醇(HDL-C)时间框架:基线,3个月,6个月;描述:以mg/dl测量的血清HDL胆固醇。 参考值:男性40 mg/dl,女性> 50 mg/dl。 C反应蛋白(CRP)时间范围:基线,3个月,6个月;描述:用Mg/dl测量的定量血清CRP水平。 正常参考值:0.3 mg/dl。 糖化血红蛋白(HBA1C)的时间范围:基线,3个月,6个月;描述:HbA1c在血液中测得的百分比。 使用PG/mL的正常脑衍生的神经营养 |
24周
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双能X射线吸收法(DXA)
大体时间:8个月
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这项研究采用双能X射线吸收法(DXA),这是一种评估骨骼健康的广泛使用且临床上安全的方法。
DXA系统(以前出版物中引用的品牌)通过发射低辐射剂量(±10μSV)X射线束来测量X射线穿透通过身体组织的程度。
根据吸收数据,该设备计算骨矿物质密度(BMD)。
由于骨骼吸收更多的X射线并具有高渗透性,而脂肪吸收较少,并且具有较低的渗透性,因此DXA有效地区分了组织类型。
DXA结果通常使用BMD的T评分来解释。
T评分≥-1.0表示正常的骨密度和良好的骨骼健康。
-2.5和-1.0之间的T评分表明骨骼质量低(骨质减少),表明BMD降低,但尚未达到骨质疏松症的阈值。
T评分≤ -2.5定义了骨质疏松症,表明BMD显着降低,裂缝风险更高。
当T评分≤ -2.5时,诊断出严重的骨质疏松症。
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8个月
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生活质量问卷
大体时间:24周
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台湾版本的世界卫生组织生活质量问卷调查是一个缩短版本,该版本源自世界卫生组织开发的原始100个项目WHOQOL-100。
问卷的探索性和验证性因素分析支持一个四域模型,该模型包括身体健康,心理健康,社会关系和环境。
这四个域的内部一致性(Cronbach'sα)范围为0.70至0.77。
问卷包括28个项目:一项总体生活质量,一项用于一般健康,身体健康的7个,六个用于心理健康,社会关系3个,环境因素为8个。
该量表根据频率,强度,能力和评估使用5点李克特格式。
得分较高,表明生活质量更高。
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24周
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合作者和调查者
调查人员
- 学习椅:Chang Shu Fang, professor、National Taipei University of Nursing and Health Sciences
出版物和有用的链接
一般刊物
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