A Worldwide Cancer Registry Enrolling Participants Profiled With a Next-Generation Sequencing Test

May 26, 2026 updated by: Hoffmann-La Roche

A Registry to Collect Characteristics and Outcomes From Patients With Solid Tumors Profiled With a Next-Generation Sequencing Test (WAYFIND-R)

WAYFIND-R is a registry that aims to capture high-quality real-world data linking next-generation sequencing, treatments and outcomes from cancer patients diagnosed with a solid tumour. The WAYFIND-R has three main overarching objectives: 1. To provide a platform to support the design and conduct of clinical and epidemiological research; 2. To develop an evidence-generation platform to better understand health outcomes and cancer care processes; and 3. To characterize the treatments and clinical course of solid tumor cancers in patients who have undergone NGS testing.

Study Overview

Status

Status

Indicates the current recruitment status or the expanded access status.
Completed

Conditions

Conditions

The disease, disorder, syndrome, illness, or injury that is being studied. On ClinicalTrials.gov, conditions may also include other health-related issues, such as lifespan, quality of life, and health risks.

Study Type

Study Type

Describes the nature of a clinical study. Study types include interventional studies (also called clinical trials), observational studies (including patient registries), and expanded access.
Observational

Enrollment (Actual)

Enrollment

The number of participants in a clinical study. The "anticipated" enrollment is the target number of participants that the researchers need for the study.
7864

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact

The name and contact information for the person who can answer enrollment questions for a clinical study. Each location where the study is being conducted may also have a specific contact, who may be better able to answer those questions.

Study Locations

  • Argentina
      • Buenos Aires, Argentina, 1426
        • Instituto Alexander Fleming
      • Buenos Aires, Argentina, C1431FWN
        • CEMIC
  • Austria
      • Graz, Austria, 8036
        • Lkh-Univ. Klinikum Graz
  • Brazil
      • Rio de Janeiro, Brazil
        • D'or Instituto de Pesquisa e Educação
      • São Paulo, Brazil, 01321-00
        • Beneficência Portuguesa de São Paulo
    • Rio Grande do Sul
      • Porto Alegre, Rio Grande do Sul, Brazil, 90035-001
        • Hospital Moinhos de Vento
    • São Paulo
      • São Paulo, São Paulo, Brazil, 01246-000
        • Instituto do Câncer do Estado de São Paulo - ICESP
      • São Paulo, São Paulo, Brazil, 01323-903
        • Hospital Alemao Oswaldo Cruz
  • Canada
    • Alberta
      • Calgary, Alberta, Canada, T2N 4N2
        • Alberta Health services
    • Ontario
      • Ottawa, Ontario, Canada, K1H 8L6
        • The Ottawa Hospital - General Campus
  • Chile
      • Las Condes, Chile, 7560908
        • Medicina de Precisión - Celerity
      • Santiago, Chile, 8330074
        • Centro de Cancer Pontificie Universidad Catolica de Chile
  • Colombia
      • Bogota, D.C., Colombia, 110131
        • Fundación CTIC - Centro de Tratamiento e Investigación sobre Cáncer Luis Carlos Sarmiento Angulo
      • Bogotá, Colombia
        • Fundacion Cardioinfantil
      • Bogotá, Colombia
        • Organizacion Sanitas Internacional
      • Cali, Colombia
        • Fundacion Clinica Valle del Lili
      • Medellín, Colombia, 050024
        • Instituto Cancerología Medellin
      • Medellín, Colombia, 50010
        • Clinica ASTORGA
  • Egypt
      • Cairo, Egypt
        • International Medical Center
  • Estonia
      • Tallinn, Estonia, 13419
        • North Estonia Medical Centre Foundation
      • Tallinn, Estonia, 11312
        • East Tallinn Central Hospital
      • Tartu, Estonia, 51014
        • Tartu Uni Hospital
  • France
      • Amiens, France, 80054
        • Chu Amiens - Picardie
      • Besançon, France, 25030
        • Hôpital Jean Minjoz
      • Brest, France, 29200
        • CHU Brest - Hôpital Morvan
      • Béthune, France, 62408
        • Centre Hospitalier de Béthune-Beuvry
      • Caen, France, 14076
        • Centre François Baclesse
      • Chauny, France, 02300
        • Centre Hospitalier de Chauny
      • Clermont-Ferrand, France, 63011
        • Centre Jean Perrin
      • Creil, France, 60109
        • Groupe Hospitalier Public Du Sud De L'Oise GHPSO
      • Dijon, France, 21079
        • Centre Hospitalier Universitaire Dijon-Bourgogne
      • Levallois-Perret, France, 92300
        • Hôpital Franco-Britannique- Fondation Cognacq-Jay
      • Lille, France, 59020
        • Centre Oscar Lambret
      • Lyon, France, 69373
        • Centre Léon Bérard
      • Marseille, France, 13385
        • APHM
      • Marseille, France, 13385
        • Hopital de La Timone - CHU de Marseille
      • Montpellier, France, 34298
        • Institut régional du Cancer de Montpellier
      • Paris, France, 75005
        • Institut Curie
      • Quimper, France, 29107
        • CH de Cornouailles
      • Rennes, France, 35000
        • Centre Eugene Marquis
      • Saint-Etienne, France, 42055
        • CHU Saint Etienne - Hôpital Nord
      • Saint-Etienne, France, 42100
        • Hôpital Privé de la Loire, Ramsay Saint Etienne
      • Toulon, France, 83056
        • CHI de Toulon - Hopital Sainte Musse
      • Villejuif, France, 94800
        • Gustave Roussy
  • Germany
      • Bad Saarow, Germany, 15526
        • HELIOS Klinikum Bad Saarow
      • Berlin, Germany, 12559
        • DRK Kliniken Berlin
      • Halle, Germany, 06120
        • Universitätsklinikum Halle (Saale)
      • Hamburg, Germany, 22763
        • Asklepios Klinik Altona
      • Hanover, Germany, 30625
        • Medizinische Hochschule Hannover
      • Heilbronn, Germany, 74078
        • SLK-Kliniken Heilbronn GmbH;Klinik für Innere Medizin III
      • Mönchengladbach, Germany, 41066
        • Praxis für Hämatologie, Onkologie und Palliativmedizin
      • Reutlingen, Germany, 72764
        • Klinikum am Steinenberg / Ermstalklinik
      • Stuttgart, Germany, 70174
        • Katharinenhospital Stuttgart
      • Wesel, Germany, 46483
        • Marien-Hospital Wesel
  • Greece
      • Asvestochóri, Greece, 570 10
        • General Hospital "G.Papanikolaou"
      • Athens, Greece, 115 28
        • Alexandras General Hospital of Athens
      • Athens, Greece, 115 26
        • Henri Dunant Hospital
      • Faliro, Greece, 185 47
        • Metropolitan Hospital Fourth Oncology Clinic
      • Thessaloniki, Greece, 546 22
        • Bioclinic Thessaloniki
  • Hungary
      • Budapest, Hungary, 1122
        • Országos Onkológiai Intézet
      • Kecskemét, Hungary, 6000
        • Bacs-Kiskun Varmegyei Oktatokorhaz
      • Pécs, Hungary, 7623
        • Pecsi Tudomanyegyetem
  • India
    • Karnataka
      • Bangalore, Karnataka, India, 560017
        • Manipal Hospital
      • Banglore, Karnataka, India, 560027
        • HealthCare Global Enterprises Limited
    • Maharashtra
      • Mumbai, Maharashtra, India, 400012
        • Tata Memorial Hospital
      • Mumbai, Maharashtra, India, 400036
        • MOC Cancer Care & Research Centre (Unit of Cellcure Cancer Centre Pvt Ltd)
      • Thane, Maharashtra, India, 401107
        • Bhaktivedanta Hospital and Research Institute
    • National Capital Territory of Delhi
      • New Delhi, National Capital Territory of Delhi, India, 110017
        • Max Super Speciality Hospital
    • Tamil Nadu
      • Chennai, Tamil Nadu, India, 600035
        • Apollo Hospitals
    • Telangana
      • Hyderabad, Telangana, India, 500034
        • Indo-American Cancer Hospital & Research Center
  • Ireland
      • CO Offaly, Ireland, R35 NY51
        • Mid-Land Regional Hospital Tullamore
      • Dublin, Ireland, 8
        • St James's Hospital
      • Dublin, Ireland, D18 AK68
        • Beacon Hospital
      • Dublin, Ireland, 4
        • St Vincent'S Uni Hospital
      • Dublin, Ireland, 24
        • Adelaide & Meath Hospital, Dublin, Incorporating the National Children's Hospital
  • Israel
      • Jerusalem, Israel, 9112001
        • Hadassah University Hospital - Ein Kerem
      • Tel Aviv, Israel, 6423906
        • Sourasky / Ichilov Hospital
  • Lebanon
      • Beirut, Lebanon, 1107 2020
        • American University of Beirut - Medical Center
      • Beirut, Lebanon, 2063 1111
        • Hotel Dieu de France
      • Saida, Lebanon, 6520
        • Hammoud Hospital
  • Mexico
      • Mexico City, Mexico, 01120
        • The American British Cowdray Hospital/ Hospital Abc
    • Mexico CITY (federal District)
      • Mexico City, Mexico CITY (federal District), Mexico, 03810
        • Oncare Viaducto Nápoles
      • Puebla City, Mexico CITY (federal District), Mexico
        • Clínica Integral Internacional de Oncología S de RL de CV
  • Philippines
      • Cebu City, Philippines, 6000
        • Cebu Doctors' University Hospital
      • Davao City, Philippines, 8000
        • Metro Davao Medical and Research Center
      • Quezon City, Philippines, 1102
        • St Lukes Medical Center
  • Poland
      • Warsaw, Poland, 02-781
        • Narodowy Instytut Onkologii im. M. Sklodowskiej-Curie
  • Portugal
      • Porto, Portugal, 4100-180
        • Hospital CUF Porto
      • Porto, Portugal, 4200-072
        • IPO do Porto
  • Saudi Arabia
      • Riyadh, Saudi Arabia, 11426
        • National Guard King Abdulaziz Medical City
  • Serbia
      • Belgrade, Serbia, 11080
        • University Hospital Medical Center Bezanijska Kosa
      • Belgrade, Serbia
        • Oncomed-System
      • Belgrade, Serbia
        • SIRIUS Medical
      • Belgrade, Serbia
        • Special hospital for internal diseases Vesalius
      • Kamenitz, Serbia, 21204
        • Oncology Institute of Vojvodina
  • Slovakia
      • Bratislava, Slovakia, 833 10
        • Narodny onkologicky ustav
  • Slovenia
      • Golnik, Slovenia, 4204
        • University Clinic Golnik
      • Ljubljana, Slovenia, 1000
        • Institute of Oncology Ljubljana
  • South Africa
      • Bloemfontein, South Africa, 9301
        • Iatros International
      • Johannesburg, South Africa, 2196
        • Medical Oncology Centre of Rosebank
      • Johannesburg, South Africa, 2192
        • Linksfield Oncology Inc.
      • Pretoria, South Africa, 0001
        • Wilgers Oncology Centre
  • Spain
      • Jaén, Spain, 23007
        • Complejo Hospitalario de Jaen-Hospital Universitario Medico Quirurgico
      • Málaga, Spain, 29011
        • Hospital Clinico Universitario Virgen de la Victoria;Servicio de Oncologia
      • Zaragoza, Spain, 50009
        • Hospital Universitario Miguel Servet
    • Balearic Islands
      • Palma de Mallorca, Balearic Islands, Spain, 07014
        • Hospital Universitario Son Espases
  • Taiwan
      • Kaohisung, Taiwan, 833
        • Chang Gung Medical Foundation - Kaohsiung
      • Taipei, Taiwan, 112
        • Taipei Veterans General Hospital
      • Taoyuan County, Taiwan, 333
        • Chung Gung Memorial Hospital
  • Thailand
      • Bangkok, Thailand, 10330
        • Chulalongkorn Hospital
      • Bangkok, Thailand, 10700
        • Faculty of Med. Siriraj Hosp.
  • Turkey (Türkiye)
      • Ankara, Turkey (Türkiye), 06520
        • Memorial Ankara Hastanesi
      • Edirne, Turkey (Türkiye), 22030
        • Trakya University Medical Faculty
      • Istanbul, Turkey (Türkiye), 34214
        • Ba?c?lar Medipol Mega Üniversite Hastanesi
      • Istanbul, Turkey (Türkiye), 34750
        • Medicana International Atasehir Hospital
      • Izmir, Turkey (Türkiye), 35170
        • Medicana International Izmir Hospital
      • Sar?yer/?stanbul, Turkey (Türkiye), 34457
        • Ac?badem Maslak Hastanesi Büyükdere
      • Seyhan/Adana, Turkey (Türkiye), 01130
        • Ac?badem Adana Hospital, Oncology Department
    • Enter Text
      • Istanbul, Enter Text, Turkey (Türkiye), 34394
        • Medicana International Zincirlikuyu Hospital
  • United Arab Emirates
      • Al Ain City, United Arab Emirates, 15258
        • Tawam Hospital
      • Dubai, United Arab Emirates
        • Mediclinic City Hospital
  • United Kingdom
      • Blackpool, United Kingdom, FY3 8NR
        • Blackpool Victoria Hospital
      • Bristol, United Kingdom, BS2 8ED
        • Bristol Haematology and Oncology Centre
      • Eastbourne, United Kingdom, BN2 1ES
        • Royal Sussex County Hospital
      • Exeter, United Kingdom, EX2 5DW
        • Royal Devon & Exeter Hospital
      • Gloucester, United Kingdom, GL1 3NN
        • Gloucestershire Royal Hospital
      • Guildford, United Kingdom, GU2 7XX
        • Royal Surrey County Hospital
      • London, United Kingdom, SW17 0RE
        • St Georges University Hospitals NHS Foundation Trust
      • New Castle Upon Tyne, United Kingdom, NE7 7DN
        • Freeman Hospital
      • Northwood, United Kingdom, HA6 2RN
        • Mount Vernon Hospital
      • Somerset, United Kingdom, TA1 5DA
        • Musgrove Park Hospital
      • Sutton in Ashfield, United Kingdom, NG17 4JL
        • Kings Mill Hospital
      • Torquay, United Kingdom, TQ2 7AA
        • Torbay Hospital
  • Vietnam
      • Hanoi, Vietnam, 100000
        • K Hospital
      • Hanoi, Vietnam, 100000
        • Hanoi Oncology Hospital
      • Ho Chi Minh City, Vietnam
        • Ho Chi Minh City Oncology Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Eligibility Criteria

The key requirements that people who want to participate in a clinical study must meet or the characteristics they must have. Eligibility criteria consist of both inclusion criteria (which are required for a person to participate in the study) and exclusion criteria (which prevent a person from participating). Types of eligibility criteria include whether a study accepts healthy volunteers, has age or age group requirements, or is limited by sex.

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Male and Female adult participants who are diagnosed with solid tumour cancers (at any anatomical location) and at any stage of the disease who have undergone an NGS test.

Description

Inclusion Criteria:

  • Participant is an adult (according to the age of majority as defined by local regulations)
  • Participant is currently diagnosed with any type of solid tumour cancer, at any stage of the disease, at the enrollment date (informed consent date)
  • Participant has undergone NGS testing, no longer than 3 months prior to the enrollment date, irrespective of the availability of test results
  • Informed consent has been obtained from the participant or legally authorized representative, as per local regulations

Exclusion Criteria:

-Participant has a prior or current diagnosis of haematological malignancy

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Other
  • Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Primary Outcome Measures

In a clinical study's protocol, the planned outcome measure that is the most important for evaluating the effect of an intervention/treatment. Most clinical studies have one primary outcome measure, but some have more than one.
Outcome Measure
Time Frame
Overall Survival
Time Frame: From date of registry entry until death, for up to 5 years
From date of registry entry until death, for up to 5 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sponsor

The organization or person who initiates the study and who has authority and control over the study.
Hoffmann-La Roche

Investigators

Investigators

A researcher involved in a clinical study. Related terms include site principal investigator, site sub-investigator, study chair, study director, and study principal investigator.
  • Study Director: Clinical Trials, Hoffmann-La Roche

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

Study Start

The actual date on which the first participant was enrolled in a clinical study. The "anticipated" study start date is the date that the researchers think will be the study start date.
August 27, 2020

Primary Completion (Actual)

Primary Completion

The date on which the last participant in a clinical study was examined or received an intervention to collect final data for the primary outcome measure. Whether the clinical study ended according to the protocol or was terminated does not affect this date. For clinical studies with more than one primary outcome measure with different completion dates, this term refers to the date on which data collection is completed for all the primary outcome measures. The "anticipated" primary completion date is the date that the researchers think will be the primary completion date for the study.
April 24, 2026

Study Completion (Actual)

Study Completion

The date on which the last participant in a clinical study was examined or received an intervention/treatment to collect final data for the primary outcome measures, secondary outcome measures, and adverse events (that is, the last participant's last visit). The "anticipated" study completion date is the date that the researchers think will be the study completion date.
April 24, 2026

Study Registration Dates

First Submitted

First Submitted

The date on which the study sponsor or investigator first submitted a study record to ClinicalTrials.gov. There is typically a delay of a few days between the first submitted date and the record's availability on ClinicalTrials.gov (the first posted date).
August 25, 2020

First Submitted That Met QC Criteria

First Submitted That Met QC Criteria

The date on which the study sponsor or investigator first submits a study record that is consistent with National Library of Medicine (NLM) quality control (QC) review criteria. The sponsor or investigator may need to revise and submit a study record one or more times before NLM's QC review criteria are met. It is the responsibility of the sponsor or investigator to ensure that the study record is consistent with the NLM QC review criteria.
August 25, 2020

First Posted (Actual)

First Posted

The date on which the study record was first available on ClinicalTrials.gov after National Library of Medicine (NLM) quality control (QC) review has concluded. There is typically a delay of a few days between the date the study sponsor or investigator submitted the study record and the first posted date.
August 27, 2020

Study Record Updates

Last Update Posted (Actual)

Last Update Posted

The most recent date on which changes to a study record were made available on ClinicalTrials.gov. There may be a delay between when the changes were submitted to ClinicalTrials.gov by the study's sponsor or investigator (the last update submitted date) and the last update posted date.
May 27, 2026

Last Update Submitted That Met QC Criteria

Last Update Submitted That Met QC Criteria

The most recent date on which the study sponsor or investigator submitted changes to a study record that are consistent with National Library of Medicine (NLM) quality control (QC) review criteria. It is the responsibility of the sponsor or investigator to ensure that the study record is consistent with the NLM QC review criteria.
May 26, 2026

Last Verified

Last Verified

The most recent date on which the study sponsor or investigator confirmed the information about a clinical study on ClinicalTrials.gov as accurate and current. If a study with a recruitment status of recruiting; not yet recruiting; or active, not recruiting has not been confirmed within the past 2 years, the study's recruitment status is shown as unknown.
May 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

Other Study ID Numbers

Identifiers or ID numbers other than the NCT number that are assigned to a clinical study by the study's sponsor, funders, or others. These numbers may include unique identifiers from other trial registries and National Institutes of Health grant numbers.
  • MX39897

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

For eligible studies, qualified researchers may request access to individual patient level clinical data. See Roche's commitment to transparency of clinical study information here: https://go.roche.com/data_sharing

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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