Impact of Spontaneous Breathing on Ventilation Distribution in Obese Patients

June 24, 2011 updated by: Technische Universität Dresden
General anesthesia (GA) and paralysis are factors which facilitate atelectasis formation, especially in obese patients. Spontaneous breathing can reduce the amount of atelectasis. In this study, the investigators are comaparing obese patients undergoing hip arthroplasty in GA versus spinal anesthesia. Distribution of ventilation during and after anesthesia is assessed by eletrical impedance tomography (EIT).

Study Overview

Status

Unknown

Conditions

Study Type

Observational

Enrollment (Anticipated)

16

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Germany
      • Dresden, Germany, 01307
        • Recruiting
        • University Hospital Carl-Gustav-Carus
        • Contact:
          • Oliver C Radke, MD, PhD, DEAA
          • Phone Number: +49 351 458-18040
          • Email: oradke@pcat.de
        • Principal Investigator:
          • Oliver C Radke, MD, PhD, DEAA

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 85 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Obese Patients aged 18-85, scheduled for elective hip arthroplasty

Description

Inclusion Criteria:

  • BMI >30
  • age 18-85
  • elective hip arthroplasty in general anesthesia or spinal anesthesia

Exclusion Criteria:

  • pregnancy/breastfeeding
  • allergies against drugs used for the anesthesia
  • contraindications for EIT
  • severe cardiac or pulmonary comorbidities
  • unable to consent or understand/follow study

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Case-Control
  • Time Perspectives: Prospective

Cohorts and Interventions

Group / Cohort
General Anesthesia
Spinal Anesthesia

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
arterial pO2 on room air
Time Frame: 24hrs
24hrs
Center of Ventilation
Time Frame: 24hrs
measured by EIT
24hrs

Secondary Outcome Measures

Outcome Measure
Time Frame
Peak Flow
Time Frame: 24hrs
24hrs

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Technische Universität Dresden

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

April 1, 2011

Study Registration Dates

First Submitted

June 22, 2011

First Submitted That Met QC Criteria

June 24, 2011

First Posted (Estimate)

June 27, 2011

Study Record Updates

Last Update Posted (Estimate)

June 27, 2011

Last Update Submitted That Met QC Criteria

June 24, 2011

Last Verified

June 1, 2011

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • SBVOBP

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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