Treating Co-Occurring Substance Use and Mental Disorders Among Jail Inmates

Treatment adaptation and implementation study for adult jail inmates with co-occurring substance use disorders.

Study Overview

• Status: Terminated
• Conditions: Implementation; Adaptation; Crime; Co-occurring Mental and Substance Use Disorders; Criminogenic Thinking
• Intervention / Treatment: Behavioral: Dual-diagnosis motivational interviewing (DDMI); Behavioral: Integrated group therapy (IGT); Behavioral: Jail and community-based behavioral health services

Detailed Description

We will adapt dual-diagnosis motivational interviewing and integrated group therapy for jail inmates with co-occurring substance use and mental health disorders and to evaluate the feasibility of implementing the adapted interventions and associated research and communication protocols.

• Study Type: Interventional
• Enrollment (Actual): 8
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • North Carolina
    • Research Triangle Park, North Carolina, United States, 27709
      • RTI International

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 65 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• (1) drug or alcohol abuse or dependence and SMI (major depressive disorder; depressive disorder not otherwise specified [NOS]; bipolar disorder I, II, or NOS; schizophrenia spectrum disorder; schizoaffective disorder; schizophreniform disorder; brief psychotic disorder; delusional disorder; or psychotic disorder NOS);
• (2) resident of Wake County and detained in The Jail;
• (3) >18 years of age; (4) able to speak/read English; and (5) able to provide informed consent.

Exclusion Criteria:

-

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: DDMI-IGT; Subjects randomized to the experimental condition will receive adapted versions of dual-diagnosis motivational interviewing ([DDMI] one session before release from jail) and integrated group therapy ([IGT] 12 community-based sessions over a 2-month period).	Behavioral: Dual-diagnosis motivational interviewing (DDMI); DDMI is an evidence-based adaptation to motivational interviewing. DDMI incorporates an integrated framework and accommodates cognitive impairments and disordered thinking associated with co-occurring substance use and mental disorders.; Behavioral: Integrated group therapy (IGT); IGT is an evidence-based practice for treating co-occurring disorders. IGT focuses on relapse prevention by reducing substance use and stabilizing psychiatric symptoms.
Active Comparator: Usual care; Subjects randomized to the usual care condition will receive jail and community-based behavioral health services.	Behavioral: Jail and community-based behavioral health services; Existing behavioral health service programs

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Acceptability	Client Satisfaction Questionnaire-8, Narrative Evaluation of Intervention Interview	Study months 21 through 34

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Feasibility of Adapted Interventions	How successfully can the adapted interventions be implemented (Focus Group interviews)	Study months 21 through 34
Fidelity	DDMI and IGT Adherence Forms	Study months 21 through 34
Substance use	Addiction Severity Index	Study months 20 through 30
Psychiatric symptoms	Brief Psychiatric Rating Scale	Study months 20 through 30
Health status	SF-12	Study months 20 through 30
Service use	Epidemiological Catchment Area Interview	Study months 20 through 30
Externalizing behaviors	Triarchic Psychopathy Measure	Study months 20 through 30
Quality of life measure	Heinrichs-Carpenter Quality of Life Scale, Plus	Study months 20 through 30
Arrest	Self-report and official jail records	Study months 20 through 30
Treatment preferences	Visual analog ranking of 8 different aspects of treatment	Study months 20 through 30

Collaborators and Investigators

• Sponsor: RTI International
• Collaborators: Boston University; University of North Carolina, Chapel Hill
• Investigators: Principal Investigator: Richard A Van Dorn, Ph.D., RTI International

Publications and helpful links

General Publications

• Van Dorn RA, Desmarais SL, Rade CB, Burris EN, Cuddeback GS, Johnson KL, Tueller SJ, Comfort ML, Mueser KT. Jail-to-community treatment continuum for adults with co-occurring substance use and mental disorders: study protocol for a pilot randomized controlled trial. Trials. 2017 Aug 4;18(1):365. doi: 10.1186/s13063-017-2088-z.

Study record dates

Study Major Dates

• Study Start (Actual): May 21, 2015
• Primary Completion (Actual): June 30, 2019
• Study Completion (Actual): June 30, 2019

Study Registration Dates

• First Submitted: August 10, 2014
• First Submitted That Met QC Criteria: August 10, 2014
• First Posted (Estimate): August 12, 2014

Study Record Updates

• Last Update Posted (Actual): March 17, 2020
• Last Update Submitted That Met QC Criteria: March 13, 2020
• Last Verified: March 1, 2020

More Information

Terms related to this study

• Keywords: feasibility; implementation; acceptability; co-occurring disorders; fidelity; Jail
• Additional Relevant MeSH Terms: Chemically-Induced Disorders; Pathologic Processes; Schizophrenia Spectrum and Other Psychotic Disorders; Substance-Related Disorders; Disease; Psychotic Disorders; Mental Disorders
• Other Study ID Numbers: R34DA036791 (U.S. NIH Grant/Contract)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES