- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02217449
Virtual Chromoendoscopy for Distal Polyps
December 10, 2020 updated by: University of Erlangen-Nürnberg Medical School
To assess the accuracy of predicting histology with virtual chromoendoscopy for distal colorectal polyps according to the ASGE PIVI statement.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Observational
Enrollment (Actual)
230
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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-
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Erlangen, Germany, 91054
- University Hospital Erlangen
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 90 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Probability Sample
Study Population
Patients undergoing screeining or surveillance colonoscopy
Description
Inclusion Criteria:
- Written informed consent
- Screening or surveillance colonoscopy
Exclusion Criteria:
- history of inflammatory bowel disease
- poor bowel preparation
- colectomy
- anticoagulation
- polyposis syndrome
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Observational Models: Cohort
- Time Perspectives: Prospective
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
HD
Prediction of histology
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Virtual Chromoendoscopy
Prediction of histology
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Effectivity of virtual chromoendoscopy
Time Frame: 3 years
|
Upon visualization of a polyp in white-light, the location and size (as compared to open biopsy forceps or snare) are noted.
Afterwards, virtual chromoendoscopy is used to visualize and enhance the mucosal vascular pattern and the mucosal surface pattern morphology of the polyp.
The endoscopist makes a real time assessment of each polyp according to size, shape, Paris classification and surface characteristics including pit pattern and mucosal vascular pattern morphology, colour, and type of depression.
Further, the endoscopist is assigning a level of confidence (high or low) to each real time prediction.
Afterwards, all polyps are resected using standard techniques and processed for pathological evaluation.
Each polyp is assessed by an experienced GI pathologist blinded to the real time prediction of polyp histology.
Finally, real time and histological results are compared.
|
3 years
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Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
January 1, 2011
Primary Completion (Actual)
August 1, 2014
Study Registration Dates
First Submitted
August 8, 2014
First Submitted That Met QC Criteria
August 13, 2014
First Posted (Estimate)
August 15, 2014
Study Record Updates
Last Update Posted (Actual)
December 14, 2020
Last Update Submitted That Met QC Criteria
December 10, 2020
Last Verified
December 1, 2020
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- HN-0010
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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