Clinical Effect of Platelet Rich Plasma Combined With Laser on Scar

March 17, 2015 updated by: Seoul National University Hospital

Clinical Study on Efficacy and Safety of Platelet Rich Plasma Combined With Laser for Scar Treatment

Investigation of Clinical Effect of Platelet Rich Plasma Combined With Laser on Acne Scar

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Platelet Rich Plasma may relieve the adverse effect of laser treatment. and it can be expected to improve acne treatment result.

Study Type

Interventional

Enrollment (Actual)

29

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Korea, Republic of
      • Seoul, Korea, Republic of, 110-744
        • Department of Dermatology, Seoul National University College of Medicine

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

19 years to 40 years (Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • moderate to severe acne scar

Exclusion Criteria:

  • taken procedures for acne scar within 6 months
  • underlying diabetes mellitus, keloid, or malignancy

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Single Group Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: fractional CO2 laser with PRP
fractional carbon dioxide laser followed by intradermal injection of platelet rich plasma
Procedure: fractional carbon dioxide laser with platelet rich plasma
fractional carbon dioxide laser followed by platelet rich plasma injection
Other Names:
  • COFRAX with autologous PRP
Active Comparator: fractional CO2 laser with NS
fractional carbon dioxide laser followed by intradermal injection of NS
Procedure: fractional carbon dioxide laser with NS
fractional carbon dioxide laser followed by normal saline injection
Other Names:
  • COFRAX with normal saline

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Global assessment of acne scar
Time Frame: 12 weeks
5-point grading of acne scar
12 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
ECCA (échelle d'évaluation clinique des cicatrices d'acné)
Time Frame: 12 weeks
quantitative analysis of acne scar
12 weeks
adverse effect assessment
Time Frame: 12 weeks
adverse effect assessment - erythema index, Epithelization Scale (0-12 point)
12 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Seoul National University Hospital

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

March 1, 2013

Primary Completion (Actual)

September 1, 2013

Study Completion (Actual)

September 1, 2013

Study Registration Dates

First Submitted

March 9, 2015

First Submitted That Met QC Criteria

March 17, 2015

First Posted (Estimate)

March 24, 2015

Study Record Updates

Last Update Posted (Estimate)

March 24, 2015

Last Update Submitted That Met QC Criteria

March 17, 2015

Last Verified

July 1, 2013

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2012-0998

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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