Diagnostic Accuracy of Doppler Resistive Indices for Early Diagnosis of Acute Kidney Injury .

November 9, 2024 updated by: Milo Engoren, University of Michigan

Diagnostic Accuracy of Renal, Carotid, and Aortic Doppler Resistive Indices for Early Diagnosis of Acute Kidney Injury Following Cardiopulmonary Bypass Surgery.

To determine if ultrasound measurement of renal and carotid arterial resistive indices are associated with post-cardiac surgery acute kidney injury.

Study Overview

Status

Completed

Conditions

Detailed Description

To determine if ultrasound measurement of renal and carotid arterial resistive indices are associated with post-cardiac surgery acute kidney injury.

Study Type

Observational

Enrollment (Actual)

100

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Michigan
      • Ann Arbor, Michigan, United States, 48109
        • Cardiovascular Center - University of Michigan

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Adult patients undergoing cardiac surgery

Description

Inclusion Criteria:

  • adult patients >= 18 years
  • undergoing cardiac surgery with cardiopulmonary bypass and transesophageal echocardiography (TEE) probe placement

Exclusion Criteria:

  • chronic kidney diseases (estimated GFR < 60 ml/min/1.73m2)
  • prior carotid endarterectomy
  • known carotid artery stenosis of 50% or greater
  • dissection or aneurysm involving renal or carotid arteries
  • scheduled aortic or aortic valve surgery
  • heart transplant
  • intraaortic balloon pump, ventricular assist device, or exctracorporeal membrane oxygenation support.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Acute kidney injury - Lassnigg grade-minimal
Time Frame: 2nd postoperative day
Based on change in creatinine
2nd postoperative day

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Michigan

Investigators

  • Principal Investigator: Milo Engoren, University of Michigan

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

October 1, 2015

Primary Completion (Actual)

April 25, 2024

Study Completion (Actual)

April 25, 2024

Study Registration Dates

First Submitted

October 17, 2015

First Submitted That Met QC Criteria

October 17, 2015

First Posted (Estimated)

October 20, 2015

Study Record Updates

Last Update Posted (Actual)

November 12, 2024

Last Update Submitted That Met QC Criteria

November 9, 2024

Last Verified

November 1, 2024

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 1 (Mobile Health and Wellness Program)

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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