Comparison of Simultaneous Endotracheal Tube Insertion With GlideScope Use

Comparison of Simultaneous Endotracheal Tube Insertion With GlideScope Use: a Pilot Study

Patients presenting for elective surgery requiring orotracheal intubation will be randomized to having the ETT inserted into the pharynx simultaneous to GlideScope insertion and then having the ETT advanced under GlideScope guidance into the trachea, or, being intubated in the more common fashion with the GlideScope being inserted first and having the ETT then advanced via the pharynx into the trachea.

Study Overview

• Status: Completed
• Conditions: Intubation; Videolaryngoscopy
• Intervention / Treatment: Procedure: Simultaneous Intubation; Procedure: Standard Intubation

Detailed Description

Patients presenting for elective surgery requiring orotracheal intubation will be randomized to having the ETT inserted into the pharynx simultaneous to GlideScope insertion and then having the ETT advanced under GlideScope guidance into the trachea, or, being intubated in the more common fashion with the GlideScope being inserted first and having the ETT then advanced via the pharynx into the trachea. The primary outcome is time to intubation. Secondary outcomes include: 1) Ease of intubation as noted by operator (measured on a 10-cm Visual Analogue Scale) 2) Number of intubation attempts 3) Number of failures to intubate 4) Use of external laryngeal pressure 5) Laryngoscopic grade distribution

• Study Type: Interventional
• Enrollment (Actual): 50
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Canada
  • Ontario
    • London, Ontario, Canada, N6A 4V2
      • St. Joseph's Health Care
    • London, Ontario, Canada, N6A5A5
      • London Health Sciences Center University Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 80 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

1) Adult patient booked for elective surgery requiring orotracheal intubation

Exclusion Criteria:

1. Any patient in whom the use of the GlideScope is contraindicated in the opinion of the attending anesthesiologist.
2. Any patient with cervical spine abnormalities.
3. Any patients with known or probable difficult airways.
4. Any patient requiring rapid sequence induction.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Simultaneous; Simultaneous Intubation with GlideScope and ETT inserted simultaneously	Procedure: Simultaneous Intubation; Intubation with GlideScope and ETT inserted simultaneously
Active Comparator: Control Standard; Standard Intubation with GlideScope inserted first and ETT inserted after the GlideScope view is obtained	Procedure: Standard Intubation; Intubation with GlideScope inserted first and ETT insertion after the GlideScope view is obtained

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Duration of Intubation	Duration of Intubation from mask removal to confirmation of ETCO2	During the intubation

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Ease of Intubation	100 mm visual analog scale	Within 5 minutes of the completion of the intubation
Number of intubation attempts	Number of intubation attempts	Within 5 minutes of the completion of the intubation
Failure to intubate	Failure to intubate	Within 5 minutes of the completion of the intubation
Laryngoscopic Grade	Cormack & Lehane grade	Within 5 minutes of the completion of the intubation
Oropharyngeal Trauma	Blind suction of the oropharynx immediately post intubation	Within 5 minutes of the completion of the intubation

Collaborators and Investigators

• Sponsor: Lawson Health Research Institute
• Investigators: Principal Investigator: Timothy Turkstra, University of Western Ontario, Canada

Publications and helpful links

General Publications

• Turkstra TP, Turkstra DC, Pavlosky AW, Jones PM. Simultaneous en bloc endotracheal tube insertion with GlideScope(R) Titanium video laryngoscope use: a randomized-controlled trial. Can J Anaesth. 2020 Nov;67(11):1515-1523. doi: 10.1007/s12630-020-01778-2. Epub 2020 Aug 19.

Study record dates

Study Major Dates

• Study Start (Actual): October 1, 2016
• Primary Completion (Actual): June 30, 2018
• Study Completion (Actual): June 30, 2018

Study Registration Dates

• First Submitted: May 25, 2016
• First Submitted That Met QC Criteria: May 27, 2016
• First Posted (Estimate): June 1, 2016

Study Record Updates

• Last Update Posted (Actual): March 1, 2019
• Last Update Submitted That Met QC Criteria: February 27, 2019
• Last Verified: February 1, 2019

More Information

Terms related to this study

• Keywords: D007440
• Other Study ID Numbers: 107322

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO