Mortality in Pediatric Intensive Care Unit

Epidemiology of Death in the PICU of Southeast China

With the development of national economy and medical technology, patients can extend life rely on high-end medical facilities. At the same time, the continued treatment cannot bring benefits to children, even resulting in poor quality of life of children and bringing high medical costs. This makes the limited medical resources are unreasonable distributed. Research showed that PICU mortality rate halved over ten years ago, but the data did not include death cases who left hospital before death. However, the death number of out-hospital were more than death in-hospital. Therefore, the data cannot actually reflect China's mortality rate of PICU. The reason analysis was limited to the cause of the disease, and does not take the social, economic factors into account. This study include eight PICUs of children's Hospital PICU. Critically ill patients are prospectively studied from death risk factors, admission status, disease diagnosis, severity of illness, analyzing of the risk factors of death from disease diagnosis and death risk factors. In addition, we will illuminate the relationship of death and economic factor, especially for who died out-hospital after withdraw or stop treatment.

Study Overview

• Status: Completed
• Conditions: Intensive Care Units, Pediatric
• Intervention / Treatment: Other: death

• Study Type: Observational
• Enrollment (Actual): 5000

Contacts and Locations

Study Locations

• China
  • Shanghai, China
    • Children'S Hosptial of Fuan University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 4 weeks to 18 years (ADULT, CHILD)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

ALL patients admitted to the PICU of eight study centers

Description

Inclusion Criteria:

• ALL patients admitted to the PICU of eight study centers

Exclusion Criteria:

• Postoperative monitoring of patients with stable hemodynamics
• PCIS score >90 and not up to the United States PICU admission standards

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Pediatric Critical Illness Score（PCIS）	first 24 hours after admission
Pediatric Risk of Mortality score (PRISM III)	24 hours
Pediatric logistic organ dysfunction (PELOD) score	24hour

Secondary Outcome Measures

Outcome Measure	Time Frame
all cause mortality	one year

Collaborators and Investigators

• Sponsor: Children's Hospital of Fudan University
• Investigators: Principal Investigator: LU guoping, doctor, Children's Hhospital of Fudan University

Study record dates

Study Major Dates

• Study Start (Actual): August 1, 2016
• Primary Completion (Actual): July 31, 2017
• Study Completion (Actual): April 1, 2018

Study Registration Dates

• First Submitted: October 26, 2016
• First Submitted That Met QC Criteria: November 9, 2016
• First Posted (Estimate): November 10, 2016

Study Record Updates

• Last Update Posted (Actual): April 10, 2018
• Last Update Submitted That Met QC Criteria: April 9, 2018
• Last Verified: April 1, 2018

More Information

Terms related to this study

• Other Study ID Numbers: fdpicu-01

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO