Characterization of Fingertips Using MRI Images (FINGERS-COMPRESSION)

Characterization of Fingertips Using MRI Images : Development of Mechanically Faithful Models Dedicated to Manipulation.

The objectives was to obtain MRI images of the index finger of the subjects without loading and with loadings (normal and shear forces from 1 to 4N).

Study Overview

• Status: Completed
• Conditions: Healthy
• Intervention / Treatment: Other: Compression of the fingertip under MRI.

• Study Type: Interventional
• Enrollment (Actual): 8
• Phase: Not Applicable

Contacts and Locations

Study Locations

• France
  • Bron, France, 69675
    • IFSTTAR

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 65 years (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Active voluntary healthy adult aged 18 to 65, affiliated to a social security scheme
• Stature between 170 and 179cm
• Body mass index (BMI) between 20 and 25
• No previous hand musculoskeletal disorders
• Cognitive level compatible with oral communication, adherence to instructions and understanding of gestures
• Having signed the consent to participate in the study

Exclusion Criteria:

• the subject presents a neurological or orthopedic disorder ;
• the subject presents a pathology that could disturb the task ;
• the subject has an Magnetic Resonance Imaging (MRI) contraindication (wears a pacemaker, insulin pump, prothesis, etc, has claustrophobia, …)

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Basic Science
• Allocation: Non-Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Group no manual work or activity; Subject with an office or student job.	Other: Compression of the fingertip under MRI.; Compression of the fingertip by a static loading on the phalanx distal of the index of the subjects; Then also a shear stress in the transverse direction of the finger. The data provided by the MRI images will be geometric information such as the thickness of the skin and its possible variation as a function of the area of the finger, the total thickness of soft tissues in compression as a function of the variation in l The angle between the axis of the phalanx and the plane of contact; Mechanical type information relating to the displacements and reaction forces, to the internal deformations of the different areas of the finger.
Sham Comparator: Group manual work; Subject working in a manual or predominantly manual.	Other: Compression of the fingertip under MRI.; Compression of the fingertip by a static loading on the phalanx distal of the index of the subjects; Then also a shear stress in the transverse direction of the finger. The data provided by the MRI images will be geometric information such as the thickness of the skin and its possible variation as a function of the area of the finger, the total thickness of soft tissues in compression as a function of the variation in l The angle between the axis of the phalanx and the plane of contact; Mechanical type information relating to the displacements and reaction forces, to the internal deformations of the different areas of the finger.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Average fingertip deflection under compression	The different stresses will be: compression of the fingertip by a static loading on the phalanx distal of the index of the subjects; Then also a shear stress in the transverse direction of the finger.	Day 1

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Average fingertip dimensions	In order to develop realistic biomechanical models of the fingers allowing the simulation of the grip, an essential step will be the experimental mechanical characterization of the distal phalanges.	Day 1

Collaborators and Investigators

• Sponsor: Hospices Civils de Lyon
• Investigators: Principal Investigator: Georges BARATON, MD, IFSTTAR

Publications and helpful links

General Publications

• Dallard J, Merlhiot X, Petitjean N, Duprey S. MRI-based experimentations of fingertip flat compression: Geometrical measurements and finite element inverse simulations to investigate material property parameters. J Biomech. 2018 Jan 23;67:166-171. doi: 10.1016/j.jbiomech.2017.11.024. Epub 2017 Nov 29.

Study record dates

Study Major Dates

• Study Start (Actual): July 21, 2015
• Primary Completion (Actual): July 24, 2015
• Study Completion (Actual): July 24, 2015

Study Registration Dates

• First Submitted: February 21, 2017
• First Submitted That Met QC Criteria: March 1, 2017
• First Posted (Actual): March 7, 2017

Study Record Updates

• Last Update Posted (Estimated): September 3, 2025
• Last Update Submitted That Met QC Criteria: August 26, 2025
• Last Verified: August 1, 2025

More Information

Terms related to this study

• Keywords: MRI, fingers compression
• Other Study ID Numbers: 69HCL16_0688

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No