CArdioSurgEry Atrial Fibrillation Register (CASE-AF)

CArdioSurgEry Atrial Fibrillation Register - CASE-AF Register

CASE AF aims to describe the reality of medical care of patients in whom atrial fibrillation is treated by cardiac surgical ablation.

Study Overview

• Status: Recruiting
• Conditions: Atrial Fibrillation

Detailed Description

CASE AF aims to describe the reality of medical care of patients in whom atrial fibrillation is treated by cardiac surgical ablation. In particular, the following questions should be answered:

• Indication: Which are the different indications for cardiac surgical ablation in patients with atrial fibrillation?
• How often and in which patients the different concepts of surgery and ablation procedures are used? At the same time, how often an intervention at the left atrial appendage is carried out?
• Safety: How secure is the cardiac surgical ablation of atrial fibrillation (periprocedural, during hospital stay and during the long-term follow up)?
• Effectiveness: How effectively is the cardiac surgical ablation of atrial fibrillation (procedural success)? How often are AF recurrences in the long-term follow up?
• What is the concommitant medical treatment after surgical ablation?

• Study Type: Observational
• Enrollment (Estimated): 2000

Contacts and Locations

• Study Contact: Name: Belgin Özdemir; Phone Number: 00496215032888; Email: oezdemir@stiftung-ihf.de

Study Locations

• Germany
  • Bavaria
    • München, Bavaria, Germany, 81925
      • Recruiting
      • Klinikum Bogenhausen
      • Contact: Edgar Eszlari, MD
  • Hamburg
    • Hamburg, Hamburg, Germany, 21075
      • Not yet recruiting
      • Asklepios Harburg
      • Contact: Thorsten Hanke, MD
  • North Rhine-Westphalia
    • Bad Rothenfelde, North Rhine-Westphalia, Germany, 49214
      • Recruiting
      • Schüchtermann Kliniken
      • Contact: Jürgen Ackemann, MD

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 100 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Patients in whom atrial fibrillation is treated by cardiac surgical ablation

Description

Inclusion Criteria:

• Atrial fibrilation
• Treated by cardiac surgical ablation

Exclusion Criteria:

• Patient denies participation

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of major bleeding events	Documentation of procedural results and clinical short-and long-term results of the documented therapies	12 months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of major adverse cardiac events	Documentation of procedural results and clinical short-and long-term results of the documented therapies	12 months
Complications during hospital stay	Documentation of hospital mortality, nonfatal major complications	12 months

Collaborators and Investigators

• Sponsor: Stiftung Institut fuer Herzinfarktforschung
• Investigators: Principal Investigator: Thorsten Hanke, MD, Asklepios Hamburg Harburg

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2017
• Primary Completion (Estimated): December 1, 2028
• Study Completion (Estimated): December 1, 2029

Study Registration Dates

• First Submitted: March 13, 2017
• First Submitted That Met QC Criteria: March 21, 2017
• First Posted (Actual): March 27, 2017

Study Record Updates

• Last Update Posted (Estimated): December 24, 2025
• Last Update Submitted That Met QC Criteria: December 17, 2025
• Last Verified: October 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Cardiovascular Diseases; Pathologic Processes; Heart Diseases; Arrhythmias, Cardiac; Pathological Conditions, Signs and Symptoms; Atrial Fibrillation
• Other Study ID Numbers: CASE-AF

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No