- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03126253
The Burden of Childhood Anemia in Bangladesh: Does Socioeconomic Status Matter?
April 21, 2017 updated by: G.M. Rabiul Islam, Shahjalal University of Science and Technology
The Burden of Childhood Anemia in Bangladesh:
Childhood anemia is a global public health problem that is associated with life-threatening consequences such as growth retardation, impaired motor and cognitive development, and increased morbidity and mortality.
Anemia can be caused by a variety of factors such as nutritional deficiencies (i.e., iron, folic acid, vitamin B12, and vitamin A), infections (i.e., helminth), and blood disorders (i.e., hemoglobinopathies).
The World Health Organization (WHO) estimates that approximately 50% of anemia cases can be attributed to iron deficiency.
This is an estimated global average that varies widely depending upon the location in question.
The World Bank estimates for 2011 claim that approximately 55.60% of all Bangladeshi children under five years of age are suffering from anemia.
The relationship between socioeconomic status (SES) inequality and anemia among the children has never been conclusively and it is unclear if the children of the age group of 6-59 months have uniformly high levels of anemia during all the stages of development, e.g., during the infant, toddler, and preschool stages.
In addition, there is a dearth of evidence from Bangladesh, where the meaning of sociodemographic characteristics may be different from that in other countries.
Therefore, this study attempts to fill the above-mentioned lacuna by investigating and evaluating the association of SES inequality, among other explanatory variables, on the development of childhood anemia during different stages of child development and to answer the questions: (a) Is SES a factor impeding childhood anemia along with other explanatory variables?
(b) In which stage of child development, the chance of disparaging with childhood anemia is highest?
(c) Is there evidence of between child development stages differences in the strength and form of association disparities between having childhood anemia and SES? (c) What are the predictive margins for SES-associated anemia in the case of infants, toddlers, and preschool children?
The results of this analysis will be reported for elucidating the potential effects of SES and the stages of child development that are usually neglected in the conventional scientific literature.
Moreover, as anemia is one of the current key health issues in Bangladesh, it is also expected that the findings of this study would contribute significantly toward shaping the health policy strategy of the country.
Study Overview
Detailed Description
The data collected by the 2011 Bangladesh Demographic Health Survey (BDHS), conducted by the National Institute for Population Research and Training (Ministry of Health and Family Welfare, Bangladesh), will be used for the purpose of this study.
in the BDHS 2011, A nationally representative household-based sample was created through a stratified, multistage cluster sampling strategy in which 600 primary sampling units were constructed (207 in urban areas and 393 in rural areas).
The primary sampling units were derived from a sampling frame created for the 2001 Bangladeshi census from seven divisions of Bangladesh.
Households were selected randomly from each primary sampling unit.
The data pertaining to the socioeconomic and sociodemographic factors were collected using a structured open-ended interview.
The questionnaire used for this purpose was modeled on the MEASURE DHS questionnaires.
Prior to the use, these questionnaires were adapted for the use in Bangladesh through a series of meetings with a Technical Working Group (TWG) that comprised of representatives from the National Institute of Population Research and Training (NIPORT,) Mitra and Associates, the International Centre for Diarrheal Diseases and Control in Bangladesh (ICDDR, B), USAID/Bangladesh, and MEASURE DH.
The questionnaires were drafted in English and then translated into Bangla which is the national language of Bangladesh.
The translations were reviewed by the experts as well as by the volunteers and a pilot study was conducted to validate the same.
Of the total of 17,964 selected households, face-to-face interviews were successfully completed for 17,141 corresponding to a household response rate of 98%.
The subjects for the examination of anemia were 2320 children aged 6-59 months, were raised from every third household of the BDHS sample.
After excluding subjects with missing data, a total of 2068 individuals were selected for this analysis.
Study Type
Observational
Enrollment (Actual)
2320
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Sylhet, Bangladesh, 3114
- Data analysis
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
6 months to 4 years (CHILD)
Accepts Healthy Volunteers
N/A
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
children 6-59 month of age in Bangladesh
Description
Inclusion Criteria:
- Infant: Less than or equal to 12 months old
- Toddler: between 13-36 months
- Preschool children: between 37-59 month
Exclusion Criteria:
- Child 0-5 months
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Anemia
Time Frame: Baseline
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Blood hemoglobin level will be used as the parameter for diagnosing anemia.
|
Baseline
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Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Investigators
- Principal Investigator: GM MI Islam, PhD, Shahjalal University of Science and Technology
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Helpful Links
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (ACTUAL)
May 11, 2011
Primary Completion (ACTUAL)
July 8, 2011
Study Completion (ACTUAL)
January 18, 2012
Study Registration Dates
First Submitted
April 19, 2017
First Submitted That Met QC Criteria
April 21, 2017
First Posted (ACTUAL)
April 24, 2017
Study Record Updates
Last Update Posted (ACTUAL)
April 24, 2017
Last Update Submitted That Met QC Criteria
April 21, 2017
Last Verified
April 1, 2017
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- FET-CA
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Study Data/Documents
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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