- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03230617
Dynamic Hyperinflation In Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients
July 25, 2017 updated by: Nisreen Mtk, Assiut University
Evaluation Of Dynamic Hyperinflation In Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients
Chronic obstructive pulmonary disease is a common respiratory condition that is characterized by inflammation of the large and small peripheral airways , the alveoli and adjacent capillary networks.
Severe airflow obstruction that imposes a significant load on the respiratory system is a major manifestation of Chronic obstructive pulmonary disease.
The reduced expiratory airflow also causes air trapping at the end of expiration , producing alveolar pressure that are higher than atmospheric pressure before the next breath.
This condition is intrinsic positive end-expiratory pressure .
Study Overview
Status
Unknown
Conditions
Intervention / Treatment
Study Type
Observational
Enrollment (Anticipated)
100
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Suzan Salama, MSc
- Phone Number: 0101423616
- Email: Suzansalama61@yahoo.com
Study Contact Backup
- Name: Aliae Abd Rabou, MD
- Phone Number: 01222302352
- Email: aliaehussein@Gmail.com
Study Locations
-
-
-
Assiut, Egypt
- Assiut University
-
Contact:
- Nisreen Marghany Taha, MD
- Phone Number: 01019293548
- Email: Nisreen.new@Gmail.com
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
All patient who diagnosed as chronic obstructive pulmonary disease admitted to the respiratory intensive care unit, chest department, Assiut university hospital, who are mechanically ventilated.
Description
Inclusion Criteria:
- patient with acute exacerbation of Chronic obstructive pulmonary disease and respiratory failure who are intubated and mechanically ventilated.
Exclusion Criteria:
- patient with neuromuscular diseases.
- patient with pulmonary vascular diseases e.g pulmonary embolism.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Observational Models: Other
- Time Perspectives: Cross-Sectional
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
Intrinsic positive end expiratory pressure > 5
chronic obstructive pulmonary disease patient with intrinsic positive end expiratory pressure more than5
|
Mechanical ventilation, in the healthcare setting or home, helps patients breathe by assisting the inhalation of oxygen into the lungs and the exhalation of carbon dioxide.
Depending on the patient's condition, mechanical ventilation can help support or completely control breathing.
|
Auto positive end expiratory pressure < 5
chronic obstructive pulmonary disease patient with intrinsic positive end expiratory pressure less than5
|
Mechanical ventilation, in the healthcare setting or home, helps patients breathe by assisting the inhalation of oxygen into the lungs and the exhalation of carbon dioxide.
Depending on the patient's condition, mechanical ventilation can help support or completely control breathing.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
The duration of mechanical ventilation
Time Frame: 1 month
|
1 month
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Anticipated)
September 1, 2017
Primary Completion (Anticipated)
September 1, 2018
Study Completion (Anticipated)
December 31, 2018
Study Registration Dates
First Submitted
July 24, 2017
First Submitted That Met QC Criteria
July 24, 2017
First Posted (Actual)
July 26, 2017
Study Record Updates
Last Update Posted (Actual)
July 27, 2017
Last Update Submitted That Met QC Criteria
July 25, 2017
Last Verified
July 1, 2017
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- EDHMVCP
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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