- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03279653
Pancreatic Exocrine Insufficiency After Bariatric Surgery
Effect of Sleeve Gastrectomy on Pancreatic Exocrine Insufficiency.
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Mechanism of weight loss differs in bariatric surgery according to type of surgery.
With sleeve gastrectomy which has restrictive mechanism, ghrelin excretion decreases, and this condition is attributed as an additional mechanism in weight loss.
Ghrelin effects pancreatic regeneration, and loss of ghrelin may result with pancreatic insufficiency. Therefore we aimed to deteremine this association.
Study Type
Enrollment (Anticipated)
Contacts and Locations
Study Contact
- Name: Fatih Basak, MD
- Phone Number: (+0216 6321818
- Email: fatihbasak@gmail.com
Study Locations
-
-
Ümraniye
-
Istanbul, Ümraniye, Turkey, 34000
- Recruiting
- Umraniye Education and Research Hospital
-
Contact:
- Fatih Basak
- Phone Number: 5055034571
- Email: fatihbasak@gmail.com
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
Patients underwent bariatric surgery (Sleeve gastrectomy) after concordonce with NIH criteria
Exclusion Criteria:
Additional operations to sleeve gastrectomy like duodenal switch. Other bariatric operations.
Study Plan
How is the study designed?
Design Details
- Observational Models: Cohort
- Time Perspectives: Prospective
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
SleeveGastrectomy
Sleeve Gastrectomy will be performed.
Preoperative and Postoperative pancreatic enzyme sufficiency (with steatocrit or fecal elastase) will be compared.
|
Preoperative enzyme test before and after sleeve gastrectomy.
Sleeve Gastrectomy will be performed.
Preoperative (in one month) and Postoperative (after 3 months) pancreatic enzyme sufficiency (with steatocrit or fecal elastase) will be compared.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Pancreatic excorine enzyme difference
Time Frame: post operative 3 months
|
Effect of operation on pancreatic excorine enzyme
|
post operative 3 months
|
Collaborators and Investigators
Investigators
- Principal Investigator: Fatih Basak, MD, University of Health Science, Umraniye Education and Research Hospital
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- p-exocrine-insufficiency
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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