Effects of Phototherapy Associated With Sprint and Squat Training on Cardiac Autonomic Modulation

Effects of Phototherapy Associated With Sprint and Squat Training on Cardiac Autonomic Modulation: Randomized, Placebo-controlled Trial

Recent studies have shown positive results in the application of phototherapy for the improvement of performance and acceleration of the healing process of the body homeostasis. Among the methods used to assess the recovery post-exercise has cardiac autonomic modulation assessed by heart rate variability (HRV), a tool widely used in sports to evaluate medium global behavior of the autonomic nervous system. Objective: analyze and compare the effect of a special protocol of phototherapy using different light sources interacting with a combined training with an autonomic modulation of heart rate in different moments (baseline; tracking daily; recovery post-exercise and after training). Method: 45 male participants will be allocated from a stratified randomization into three groups: control (n=15), placebo (n=15) and group special protocol of phototherapy (n=15). Participants will perform a combined training of sprints and squats twice a week for twelve weeks divided into two phases. The application of phototherapy and placebo was administered in phase 2, after sprints and just before the squat. The phototherapy was used combine different light sources and wavelength (red and infrared). Was analyze HRV in five moments: baseline; traking daily; week target of phase I and II; after training. The weeks target consist of training sessions with greater energy expenditure (largest intensity). The sphericity of the data was tested by Mauchly test. In case of violation of the sphericity assumption, the correction of Greenhouse-Geisser was performed. The data was analyzed using analysis of variance for repeated measures (Bonferroni post-test), which provide information on the effects of time, group and interaction. All statistical analyzes assume the significance level of 5%.

Study Overview

• Status: Completed
• Conditions: Training; Phototherapy; Autonomic Nervous System
• Intervention / Treatment: Other: Phototherapy; Other: Placebo; Other: Passive recovery

• Study Type: Interventional
• Enrollment (Actual): 39
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Brazil
  • SP
    • Presidente Prudente, SP, Brazil, 55
      • Franciele Marques Vanderlei

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 30 years (ADULT)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: Male

Description

Inclusion Criteria:

• Healthy patient (self-report);
• Male gender;

Exclusion Criteria:

• History of cancer;
• Smokers or alcoholics;
• Use drugs that influenced cardiac autonomic activity;
• Cardiovascular, metabolic or endocrine diseases;
• Occurrence of musculoskeletal injury during the study.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: OTHER
• Allocation: RANDOMIZED
• Interventional Model: PARALLEL
• Masking: TRIPLE

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
EXPERIMENTAL: Active phototherapy group; (n=12) Phase 2 training + active phototherapy Dosage applied was 30J per site (180J per muscle) to six sites on the quadriceps The MR4 LaserShower 50 4D emitter (MultiRadiance Medical, USA). The optical power was calibrated before irradiationin each participant using a Thorlabs thermal power meter(Model S322C, Thorlabs, Newton, NJ, USA).	Other: Phototherapy; Photobiomodulation or photobiostimulation, this technique is the application of monochromatic light that can influence cellular activity through inhibition or stimulation of chemical and biological functions.
PLACEBO_COMPARATOR: Placebo group; (n=14) Phase 2 training + placebo phototherapy group	Other: Placebo; The same procedures as in the active phototherapy group was applied to the placebo group; however, the emitter was disabled. The device was emit the same sounds regardless of the programmed mode (active phototherapy).
OTHER: non-treatment control group; (n=13) Phase 2 training + control group	Other: Passive recovery; Participants was remain sat for passive recovery supervised by an independent therapist during the period when the other groups are received recovery strategies.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Effects of phototherapy on adaptation and change of cardiac Autonomic modulation.	Analyzed and compare the effects of phototherapy with different light sources and wavelengths applied during training combined at heart rate variability	Baseline (captation of hear rate variability for 20 minutes) before 6 weeks (captation of hear rate variability for 20 minutes) and before 12 weeks (captation of hear rate variability for 20 minutes)

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Effects of phototherapy on recovery of cardiac Autonomic modulation.	Compare the effects of phototherapy with placebo group and control group at recovery after exercise of heart rate variability.	During training sessions with higher energetic spending leaving for the last two weeks, composed of higher intensity - (captation of hear rate variability for 1 hour on phase 1 and phase 2).
Effects of phototherapy on tracking daily of cardiac autonomic modulation.	Analyze and compare the change in the indices of heart rate variability in tracking daily after combined training of sprints and squats	daily, after exercise and before exercise (captation of hear rate variability for 7 minutes)

Collaborators and Investigators

• Sponsor: Paulista University

Study record dates

Study Major Dates

• Study Start (ACTUAL): September 3, 2017
• Primary Completion (ACTUAL): October 1, 2017
• Study Completion (ACTUAL): December 19, 2017

Study Registration Dates

• First Submitted: May 28, 2018
• First Submitted That Met QC Criteria: June 11, 2018
• First Posted (ACTUAL): June 25, 2018

Study Record Updates

• Last Update Posted (ACTUAL): June 25, 2018
• Last Update Submitted That Met QC Criteria: June 11, 2018
• Last Verified: June 1, 2018

More Information

Terms related to this study

• Keywords: Autonomic nervous system; Photobiomodulation; Heart rate variability; Recovery of function; Super-pulsed laser; Led light
• Other Study ID Numbers: U1111-1214-0497

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No