- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03632252
Evaluating and Improving Assistive Robotic Devices Continuously and in Real-time
January 13, 2022 updated by: Deanna H Gates, University of Michigan
The goal of this research is to determine a quick, accurate and unobtrusive way to optimize the performance of powered assistive devices like ankle exoskeleton or prostheses.
Study Overview
Detailed Description
Lower limb assistive robotic devices, such as active prosthesis, orthoses, and exoskeletons have the potential to restore function for the millions of Americans who experience mobility challenges due to injury and disability.
Since individuals with mobility challenges have an increased metabolic costs of transport, the benefit of such assistive devices is commonly assessed via the reduction in the metabolic work rate of the individual who is using the device.
Currently, metabolic work rate can only be obtained in a laboratory environment, using breath-by-breath measurements of respiratory gas analysis.
To obtain a single steady state data point of metabolic work rate, multiple minutes of data must be collected, since the signals are noisy and slow.
In addition, the user has to wear a mask and bulky equipment.
The investigators propose an improved way to obtain such estimates of metabolic work rate in real-time.
In this project, the investigators will use various small sensors to optimize push-off timing for an active ankle prosthesis.
Study Type
Interventional
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Michigan
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Ann Arbor, Michigan, United States, 48109
- University of Michigan
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Has a unilateral amputation
- Has used a prosthesis for at least 6 months
Exclusion Criteria:
- History of orthopedic or neurologic disorders to their intact limb
- History of cardiovascular disease
- Unable to walk for 30 minutes at a time
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Basic Science
- Allocation: N/A
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Powered ankle prosthesis
We will use data from various sensors to optimize the amount of power provided by custom ankle ankle prosthesis.
This is a single session study lasting about 4 hours.
|
This device is a custom designed ankle prosthesis.
Motors control force on the device through cables but are not worn by the person.
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Minimum metabolic cost
Time Frame: 3 minutes
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The minimum oxygen consumption rate required for walking
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3 minutes
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Investigators
- Principal Investigator: Deanna H Gates, PhD, University of Michigan
- Principal Investigator: C D Remy, PhD, University of Michigan
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
May 1, 2019
Primary Completion (Actual)
September 1, 2021
Study Completion (Actual)
September 15, 2021
Study Registration Dates
First Submitted
August 13, 2018
First Submitted That Met QC Criteria
August 13, 2018
First Posted (Actual)
August 15, 2018
Study Record Updates
Last Update Posted (Actual)
January 14, 2022
Last Update Submitted That Met QC Criteria
January 13, 2022
Last Verified
January 1, 2022
More Information
Terms related to this study
Other Study ID Numbers
- HUM00139671
- R03HD092639 (U.S. NIH Grant/Contract)
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
No
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
Yes
product manufactured in and exported from the U.S.
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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