High-intensity Training for Improving Physical Performance of Aged Women (AHIITATE)

Effects of High-intensity Interval Circuit Training (HIICT) on the Cardiovascular and Functional Parameters of Aged Women

This study evaluates the adaptations on the functional capacity and cardiovascular in elderly after a physical activity program circuit training. The participants were divided into three groups: Circuit training based on high-intensity interval training group (HIICT), Circuit training at moderate intensity group (MICT) and Control group (CG).

Study Overview

• Status: Completed
• Conditions: Healthy; Physical Activity; Aging; Cardiovascular Risk Factor
• Intervention / Treatment: Other: Experimental: High-intensity interval training group; Other: Experimental: Moderate-intensity interval training group

Detailed Description

Three groups of participants (circuit training based on high-intensity interval training, circuit training at moderate intensity and not training group) will enter the study. The intervention will consist of a physical exercise program in day centers.

Intensity progression will be encouraged according to the rate of perceived exertion. Progression of exertion will be "very hard", "extremely hard" and "maximal exertion" for HIT group, and "light", "somewhat hard" and "hard" for group. Assessment will be undertaken at two-time points: baseline and after 16 weeks of exercise training.

Assessment will include VO2 peak, functional capacity, health-related quality of life, cognitive state and daily physical activity.

• Study Type: Interventional
• Enrollment (Actual): 54
• Phase: Not Applicable

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 50 years to 90 years (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: Female

Description

Inclusion Criteria:

1. Having 50 - 90 years old.
2. Not suffering chronic heart, respiratory or joint disease, taking medication or having a deteriorated level of mental health that could interfere in carrying out exercise programs.
3. Having 0 or 1 responses positive in the Physical Activity Readiness Questionnaire (ParQ). Only item 6, related to mild vascular diseases.
4. Being physically independent according to the scales Lawton and Brody, and Katz.

Exclusion Criteria:

1. Having uncontrolled arterial hypertension.
2. Having practiced during the previous 3 months or practicing at present a similar exercise to the one proposed in the study.
3. Attending sessions less than 80%.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Basic Science
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: High-intensity interval training group; Frequency: 2 days/weeks; Intensity: 16-18 Börg/85-100%VO2max; Recovery: Active; Duration: 1 hour.	Other: Experimental: High-intensity interval training group; 16 weeks of High-intensity interval training
Experimental: Moderate-intensity interval training group; Frequency: 2 days/weeks; Intensity: 12-14 Börg/60-70% VO2max; Recovery: Active; Duration: 1 hour.	Other: Experimental: Moderate-intensity interval training group; 16 weeks of Moderate-intensity interval training
No Intervention: Control group; Maintain their normal daily activities throughout the sixteen-week experimental period.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Analyses changes in maximum oxygen consumption (VO2max).	A modified Balke treadmill protocol will be used to estimate aerobic capacity (VO2max).	Pre and post after sixteen weeks of intervention
Analyses changes in maximum oxygen consumption (VO2max).	VO2max was assessed using the 6-Minute Walk Test. The participant should walk the longest distance possible in 6 minutes by walking continuously the 42 metres indicated on the floor. It measures the distance in meters	Pre and post after sixteen weeks of intervention

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Analyses changes in heart rate reached in ergometry.	Analyses during modified Balke treadmill protocol	Pre and post after sixteen weeks of intervention
Analyses changes in blood pressure reached in ergometry.	Analyses during modified Balke treadmill protocol	Pre and post after sixteen weeks of intervention
Analyses changes in maximum speed reached in ergometry.	Analyses during modified Balke treadmill protocol	Pre and post after sixteen weeks of intervention
Analyses changes in duration test reached in ergometry.	Analyses during modified Balke treadmill protocol	Pre and post after sixteen weeks of intervention
Analyses changes in fat percentage.	Fat percentage (%) was assessed using bioimpedance analysis (OMROM BF-306).	Pre and post after sixteen weeks of intervention.
Analyses changes in body mass index (BMI).	BMI was assessed using bioimpedance analysis (OMROM BF-306).	Pre and post after sixteen weeks of intervention.
Analyses changes in gait.	Gait was assessed using the Timed Up and Go Test. To stand up from a standard arms chair, walk 3 meters, turn back the cone walk back and sit down to the chair. The time in seconds is record.	Pre and post after sixteen weeks of intervention.
Analyses changes in balance.	Balance was assessed using the One Leg Standing Test. This test consist in maintain one leg stance for as long as possible. The test was considered normal if the one leg standing time reached 30 seconds.	Pre and post after sixteen weeks of intervention.
Analyses changes in lower body strength.	Lower body strength was assessed using the Sit To Stand 30. For the Sit To Stand 30, the participant consist in measures how many repetition the participant can to stand up and sit down during 30 seconds.	Pre and post after sixteen weeks of intervention.
Analyses changes in upper body strength.	Upper body strength was assessed using the Arm Curl Test (30). For this test, the participant consist in measures how many repetition the participant can to curl up and curl down during 30 seconds.	Pre and post after sixteen weeks of intervention.
Analyses changes in maximal handgrip strength.	To measure the amount of strength developed by each hand in kg.	Pre and post after sixteen weeks of intervention.

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Analyses change in Self Assessed Physical Activity.	Physical activity was assessed using the Physical Activity Scale of the Elderly (PASE) questionnaire. The PASE is designed to assess physical activity in older persons. The total PASE score was computed by multiplying the amount of time spent in each activity (hours/week) or participation (yes/no) in an activity by empirically derived item weights and summing over all activities. PASE scores for this study ranged from 0 to 756 with higher scores indicating more physical activity.	Pre and post after sixteen weeks of intervention.

Collaborators and Investigators

• Sponsor: Universidad de Almeria
• Investigators: Principal Investigator: Ismael Ballesta García, PhD. Student, Universidad de Almeria; Principal Investigator: María Carrasco Poyatos, PhD., Universidad de Almeria

Publications and helpful links

General Publications

• Wisloff U, Stoylen A, Loennechen JP, Bruvold M, Rognmo O, Haram PM, Tjonna AE, Helgerud J, Slordahl SA, Lee SJ, Videm V, Bye A, Smith GL, Najjar SM, Ellingsen O, Skjaerpe T. Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients: a randomized study. Circulation. 2007 Jun 19;115(24):3086-94. doi: 10.1161/CIRCULATIONAHA.106.675041. Epub 2007 Jun 4.
• Guiraud T, Juneau M, Nigam A, Gayda M, Meyer P, Mekary S, Paillard F, Bosquet L. Optimization of high intensity interval exercise in coronary heart disease. Eur J Appl Physiol. 2010 Mar;108(4):733-40. doi: 10.1007/s00421-009-1287-z.
• Huang SC, Wong MK, Lin PJ, Tsai FC, Fu TC, Wen MS, Kuo CT, Wang JS. Modified high-intensity interval training increases peak cardiac power output in patients with heart failure. Eur J Appl Physiol. 2014 Sep;114(9):1853-62. doi: 10.1007/s00421-014-2913-y. Epub 2014 Jun 1.
• Ballesta Garcia I, Rubio Arias JA, Ramos Campo DJ, Martinez Gonzalez-Moro I, Carrasco Poyatos M. High-intensity Interval Training Dosage for Heart Failure and Coronary Artery Disease Cardiac Rehabilitation. A Systematic Review and Meta-analysis. Rev Esp Cardiol (Engl Ed). 2019 Mar;72(3):233-243. doi: 10.1016/j.rec.2018.02.015. Epub 2018 Apr 9. English, Spanish.

Helpful Links

• Carrasco, M., Navarro, M.D., Martínez, I., Reche-Orenes, D. (2016). Daily physical activity impact in old women bone density and grip strength. Nutrición Hospitalaria, 33(6), 1305-1311.
• Carrasco, M., Martínez, I., Navarro, M.D. (2015). Daily physical activity and bone mineral density in older women. Revista Brasileira de Medicina do Esporte, 21(1), 22-26.
• Carrasco, M., Vaquero, M. (2012). Water training in postmenopausal women: effect on muscular strength. European Journal of Sport Science, 12(2), 193-200.

Study record dates

Study Major Dates

• Study Start (Actual): December 20, 2015
• Primary Completion (Actual): February 1, 2016
• Study Completion (Actual): June 20, 2016

Study Registration Dates

• First Submitted: September 5, 2018
• First Submitted That Met QC Criteria: February 11, 2019
• First Posted (Actual): February 15, 2019

Study Record Updates

• Last Update Posted (Actual): March 6, 2019
• Last Update Submitted That Met QC Criteria: March 4, 2019
• Last Verified: March 1, 2019

More Information

Terms related to this study

• Keywords: Elderly; High-intensity interval training; Functional capacity; Cardiovascular parameters; VO2 max; Circuit training
• Other Study ID Numbers: HIICT-OW/16

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No