The Effect of Dual Tasking on Physical and Cognitive Functions in Patients With Parkinson Disease

April 3, 2019 updated by: Tugce Kocamal, Istanbul University

Effects of Dual Task Training And Treadmill Training on Physical and Cognitive Functions in Patients With Parkinson Disease

The ability of performing multi-tasking procedures is impaired in patients with Parkinson's disease. In this study, our goal was to detect the effects of dual-task training with treadmill training on walking and balance and to compare its effects on quality of life, cognitive functions and risk of fall, to treadmill training alone.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

45

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
    • Fatih
      • Istanbul, Fatih, Turkey, 34093
        • Istanbul University Istanbul Faculty of Medicine Department of Physical Medicine and Rehabilitation

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 75 years (ADULT, OLDER_ADULT)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

The patients with Idiopathic Parkinson Disease on medication who has

  • Hoehn-Yahr 1-3
  • Mini Mental Test score 20 and above
  • Functional Ambulation Category 2 and above
  • No changes in medication in last 3 months
  • No rehabilitation programme in last 3 months

Exclusion Criteria:

  • Diagnosis of Parkinsonism other than Idiopathic Parkinson Disease
  • Global aphasia
  • Severe cognitive dysfunction
  • Other neurologic/orthopedic diseases
  • Limiting cardiovascular or pulmonary disease
  • Visual impairment
  • Hearing loss

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: TREATMENT
  • Allocation: RANDOMIZED
  • Interventional Model: PARALLEL
  • Masking: TRIPLE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Dual task
Treadmill training + cognitive tasks + standard exercise programme
Other: Dual task
The patients in the dual task group received cognitive tasks during treadmill training sessions.
Other: Treadmill Training
Standard treadmill training
Other: Standard exercise programme
Standard exercise programme for Parkinson Disease
Active Comparator: Single task
Treadmill training + standard exercise programme
Other: Treadmill Training
Standard treadmill training
Other: Standard exercise programme
Standard exercise programme for Parkinson Disease
Active Comparator: Control
Standard exercise programme
Other: Standard exercise programme
Standard exercise programme for Parkinson Disease

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
10MWT
Time Frame: 12 weeks
10 Meter Walk Test on comfortable speed
12 weeks
10MWT with cognitive tasks
Time Frame: 12 weeks
10 Meter Walk Test with cognitive tasks
12 weeks
MoCA
Time Frame: 12 weeks
Montreal Cognitive Assessment
12 weeks
TUG
Time Frame: 12 weeks
Timed Up and Go Test
12 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
PDQ-39
Time Frame: 12 weeks
Parkinson Disease Questionnaire 39
12 weeks
FES-I
Time Frame: 12 weeks
To evaluate fear of falling, all patients filled the Falls Efficacy Scale-International (FES-I). A series of 16 questions assesses the respondent's fear of falling for a range of ADLs. Each question was rated on a four-point scale.
12 weeks
Stroop Test
Time Frame: 12 weeks
Cognitive assessment for executive functions
12 weeks
FOGQ
Time Frame: 12 weeks
Freezing of Gait Questionnaire
12 weeks
Falls Diary
Time Frame: 4 weeks
Falls account
4 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Istanbul University

Investigators

  • Study Director: Ayse Yaliman, Prof, Istanbul University Istanbul Faculty of Medicine Physical Medicine and Rehabilitation
  • Study Director: Ekin Ilke Sen, MD, Istanbul University Istanbul Faculty of Medicine Physical Medicine and Rehabilitation

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 1, 2018

Primary Completion (Actual)

March 1, 2019

Study Completion (Actual)

April 1, 2019

Study Registration Dates

First Submitted

April 3, 2019

First Submitted That Met QC Criteria

April 3, 2019

First Posted (Actual)

April 4, 2019

Study Record Updates

Last Update Posted (Actual)

April 5, 2019

Last Update Submitted That Met QC Criteria

April 3, 2019

Last Verified

April 1, 2019

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 20181443

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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