Health-related Quality of Life in Colon Cancer

Health-related Quality of Life in Colon Cancer Patients

This study investigates health-related Quality of life in colon cancer patients in Västmanland, Sweden, at diagnosis, at 6 months, 1, 2 and 3 years after diagnosis, measured by the well-validated EORTC QLQ-C30 questionnaire.

Study Overview

• Status: Unknown
• Conditions: Health Related Quality of Life

Detailed Description

See above.

• Study Type: Observational
• Enrollment (Actual): 376

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

All patients diagnosed with colon cancer in Region Västmanland 2012-2016, that accepted to be included in the study after written consent.

Description

Inclusion Criteria:

All patients diagnosed with colon cancer in Region Västmanland 2012-2016.

Exclusion Criteria:

Language problems, declined inclusion,

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Health-related Quality of Life	The EORTC QLQ-C30, a HRQoL questionnaire was used. It consists of 30 items comprising five functional scales (physical, role, emotional, cognitive, and social), three symptom scales (fatigue, nausea and vomiting, and pain). Six single items are also included (dyspnoea, insomnia, appetite loss, constipation, diarrhoea, and financial difficulties). The final two items in the questionnaire assess global health and overall QoL. Raw data were transformed to standardized scores ranging from 0 to 100 using the EORTC scoring manual. A high score on the functional scale represents a high level of functioning (i.e., higher is better), whereas a high score on the symptom scale represents a high level of symptoms (i.e., lower is better).	2012-2016

Collaborators and Investigators

• Sponsor: Region Västmanland
• Investigators: Principal Investigator: Catarina Tiselius, PhD, Region Västmanland

Publications and helpful links

General Publications

• Tiselius C, Rosenblad A, Strand E, Smedh K. Risk factors for poor health-related quality of life in patients with colon cancer include stoma and smoking habits. Health Qual Life Outcomes. 2021 Sep 10;19(1):216. doi: 10.1186/s12955-021-01850-5.

Study record dates

Study Major Dates

• Study Start (Actual): March 1, 2012
• Primary Completion (Anticipated): September 1, 2019
• Study Completion (Anticipated): September 1, 2022

Study Registration Dates

• First Submitted: March 31, 2019
• First Submitted That Met QC Criteria: April 9, 2019
• First Posted (Actual): April 10, 2019

Study Record Updates

• Last Update Posted (Actual): April 12, 2019
• Last Update Submitted That Met QC Criteria: April 10, 2019
• Last Verified: March 1, 2019

More Information

Terms related to this study

• Other Study ID Numbers: HRQoL

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO
• IPD Plan Description: On request if suitable.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No