Baseline Investigation of Patients With Cardiac Arrest in China (BASIC)

BASIC is a perspective, multicentre and large-scale registry focusing on of patients suffering a cardiac arrest in China. The aims of the study are to establish the monitoring sites covering out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA) in urban and rural areas in 7 regions (East China, North China, South China, Central China, Northeast China, Southwest China and Northwest China) around China, to collect data from cardiac arrest patients, and to describe basic characteristics, treatments, outcomes, incidences and risk factors of OHCA and IHCA in China.

Study Overview

• Status: Recruiting
• Conditions: Cardiac Arrest

• Study Type: Observational
• Enrollment (Anticipated): 200000

Contacts and Locations

• Study Contact: Name: Feng Xu, Dr; Phone Number: +86-18560083066; Email: xufengsdu@126.com
• Study Contact Backup: Name: Chang Pan, Dr; Phone Number: +86-18560082290; Email: panchang0517@163.com

Study Locations

• China
  • Shandong
    • Jinan, Shandong, China, 250012
      • Recruiting
      • Qilu Hospital of Shandong University
      • Contact: Feng Xu, Dr; Phone Number: +86-18560083066; Email: xufengsdu@126.com
      • Contact: Chang Pan, Dr; Phone Number: +86-18560082290; Email: panchang0517@163.com
      • Principal Investigator: Feng Xu, Dr

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

consecutive patients with cardiac arrest

Description

Inclusion Criteria:

1. OHCA: Every patient who suffered a cardiac arrest that occurred in any location other than a hospital, and was attended and/or treated by an EMS.
2. IHCA: Every patient who suffered a cardiac arrest in hospital.
3. the representative population-based survey: Every patient who suffered a cardiac arrest in the selected cities or suburbs.

Exclusion Criteria:

1. OHCA: 1)The out-of-hospital cardiac arrest patients who were taken to the hospital by their family members; 2) Bystanders suspected cardiac arrest, but the ROSC was achieved without defibrillation or resuscitation by EMS.
2. IHCA: The patient who suffered a cardiac arrest that occurred out-of-hospital and then transferred to the hospital.

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
incidence of OHCA treated by EMS		Latest data inclusion June 30, 2022
incidence of IHCA		Latest data inclusion June 30, 2022
survival to hospital discharge or 30d survival of OHCA		at hospital discharge, 30days after cardiac arrest occurs
survival to hospital discharge or 30d survival of IHCA		at hospital discharge, 30days after cardiac arrest occurs
prevalence of favorable neurological outcome after cardiac arrest according to Cerebral Performance Category (CPC) Scale	CPC 1 and 2 as a favorable neurological outcome; CPC 1, Good Cerebral Performance; CPC 2, Moderate Cerebral Disability; CPC 3, Severe Cerebral Disability; CPC 4, Coma, vegetative state; CPC 5, Brain death	at hospital discharge, 30days after cardiac arrest occurs

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
survival of OHCA		6 months and 1 year after cardiac arrest occurs
survival of IHCA		6 months and 1 year after cardiac arrest occurs
prevalence of favorable neurological outcome after cardiac arrest according to Cerebral Performance Category (CPC) Scale	CPC 1 and 2 as a favorable neurological outcome; CPC 1, Good Cerebral Performance; CPC 2, Moderate Cerebral Disability; CPC 3, Severe Cerebral Disability; CPC 4, Coma, vegetative state; CPC 5, Brain death	6 months and 1 year after cardiac arrest occurs
rate of return of spontaneous circulation		Latest data inclusion June 30,2022

Collaborators and Investigators

• Sponsor: Qilu Hospital of Shandong University
• Collaborators: The First Affiliated Hospital of Anhui Medical University; Xiangya Hospital of Central South University; Fudan University; Peking University Third Hospital; RenJi Hospital; West China Hospital; Second Affiliated Hospital, School of Medicine, Zhejiang University; First Affiliated Hospital of Fujian Medical University; Beijing Chao Yang Hospital; China-Japan Friendship Hospital; The First Hospital of Jilin University; Henan Provincial People's Hospital; Beijing Institute of Heart, Lung and Blood Vessel Diseases; Hunan Provincial People's Hospital; Renmin Hospital of Wuhan University; The Affiliated Hospital Of Guizhou Medical University; Second Affiliated Hospital of Xi'an Jiaotong University; First Hospital of China Medical University; Capital Medical University; Chinese Academy of Medical Sciences, Fuwai Hospital; Qinghai People's Hospital; The First Affiliated Hospital of Shanxi Medical University; Shanghai Changzheng Hospital; First Affiliated Hospital of Xinjiang Medical University; The Affiliated Hospital of Xuzhou Medical University; The Affiliated Hospital of Inner Mongolia Medical University; First Affiliated Hospital of Harbin Medical University; First Affiliated Hospital of Guangxi Medical University; Chongqing Emergency Medical Center; Hainan Medical College; Beijing Emergency Medical Center; National Center for Chronic and Noncommunicable Disease Control and Prevention, China CDC; People's Hospital of Ningxia Hui Autonomous Region; Wushan County People's Hospital; Lanzhou university second hospital; Sun Yat-sen Memorial Hospital,Sun Yat-sen University; Jinan Emergency Medical Center; Wenshang County People's Hospital; Xuzhou Ambulance Center; Hefei Emergency Medical Center; Hangzhou Emergency Medical Center; Shanghai Emergency Medical Center; The First Affiliated Hospital of Nanchang Medical University; Beijing Friendship Hospital Affiliated to the Capital University of Medical Sciences; Beijing Children's Hospital Affiliated to the Capital Medical University; Beijing Red Cross Emergency Rescue Center; The General Hospital of TianJin Medical University; Tianjin Emergency Medical Center; Hohhot 120 Emergency Medical Center; Siziwang Banner People's Hospital of Inner Mongolia; First Hospital of Qinhuangdao; Qinhuangdao Emergency Dispatching Center; Taiyuan Emergency Medical Center; Guangzhou Emergency Medical Command Center; Haikou Emergency Medical Center; People's Hospital of Wanning; Nanning Emergency Medical Center; Wuhan Emergency Medical Center; Qianjiang Central Hospital; Zhenzhou Emergency Medical Center; Changchun Emergency Medical Center; Nong'an County People's Hospital; Shenyang Emergency Center; Heilongjiang Emergency Medical Center; Santai County People's Hospital; Emergency Center of Yunan Province; Nyingchi People's Hospital; Yinchuan Emergency Medical Center; Xi'an Emergency Medical Center; National Center for Cardiovascular Disease; National Health Commission of the People's Republic of China, Statistical information center; Chang shu No.1 People's Hospital
• Investigators: Principal Investigator: Feng Xu, Dr, Qilu Hospital of Shandong University

Study record dates

Study Major Dates

• Study Start (Actual): July 1, 2019
• Primary Completion (Anticipated): June 30, 2023
• Study Completion (Anticipated): December 31, 2023

Study Registration Dates

• First Submitted: April 19, 2019
• First Submitted That Met QC Criteria: April 22, 2019
• First Posted (Actual): April 24, 2019

Study Record Updates

• Last Update Posted (Actual): October 4, 2022
• Last Update Submitted That Met QC Criteria: October 2, 2022
• Last Verified: October 1, 2022

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Heart Diseases; Cardiovascular Diseases; Heart Arrest
• Other Study ID Numbers: QLEmer201904

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No