Acute Effects of HIIT and SSMIT on Intraocular Pressure Among Sedentary Individuals

Acute Effects of High Intensity Interval Training (HIIT) and Steady State Moderate Intensity Training (SSMIT) on Intraocular Pressure Among Sedentary Individuals

Purpose to study the acute effects of both forms of aerobic exercise (HIIT and SSMIT) on intraocular pressure among healthy sedentary individuals

Study Overview

• Status: Completed
• Conditions: Intraocular Pressure
• Intervention / Treatment: Other: aerobic exercise

Detailed Description

40 participants were recruited and divided into 2 groups. Each group performed 2 exercise protocols with a 4 day washout period between them.

The intraocular pressure was measured before the exercise and after the exercise in 5 minute periods up until 30 minutes post exercise.

The intraocular pressure was measured using a handheld rebound tonometer.

• Study Type: Interventional
• Enrollment (Actual): 40
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Malaysia
  • Wilayah Perseketuan
    • Kuala Lumpur, Wilayah Perseketuan, Malaysia, 59100
      • University Malaya

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 21 years to 60 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• all University hospital staff

Exclusion Criteria:

• previous ocular trauma
• surgery in the eligible eye
• known case of glaucoma or glaucoma suspect (IOP > 21mmHg)
• history of glaucoma laser procedure/surgery within 6 months in eligible eye
• unable to undergo IOP measurements
• undiagnosed visual condition
• any uncontrolled medical condition such as end stage renal failure, uncontrolled diabetes and uncontrolled hypertension

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: Triple

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Group A; undergo HIIT first then SSMIT protocol	Other: aerobic exercise; aerobic exercise HIIT : High intensity interval training SSMIT : Steady state moderate intensity training
Active Comparator: Group B; undergo SSMIT first then HIIT protocol	Other: aerobic exercise; aerobic exercise HIIT : High intensity interval training SSMIT : Steady state moderate intensity training

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Changes in intraocular pressure	changes in intraocular pressure before and after exervcise	30 minutes

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
compare which form of exercise (HIIT & SSMIT) is superior in reducing intraocular pressure	difference in intraocular pressure reduction observed between each exercise protocol	30 days

Collaborators and Investigators

• Sponsor: University of Malaya

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2018
• Primary Completion (Actual): January 31, 2018
• Study Completion (Actual): February 28, 2018

Study Registration Dates

• First Submitted: October 11, 2019
• First Submitted That Met QC Criteria: October 17, 2019
• First Posted (Actual): October 21, 2019

Study Record Updates

• Last Update Posted (Actual): October 21, 2019
• Last Update Submitted That Met QC Criteria: October 17, 2019
• Last Verified: October 1, 2019

More Information

Terms related to this study

• Other Study ID Numbers: 20171031-5738

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No