Uterine Artery Doppler and 11-14 / 20-22 Weeks of Gestation Pregnancy

Comparison of Uterine Artery Doppler Measurements Performed at 11-14 and 20-22 Weeks of Gestation During Pregnancy According to Delivery Type and Number of Births and Investigation of the Effects on Obstetric Outcomes (Maternal, Fetal, Neonatal Results)

Uterine artery doppler measurements will be made at 11-14 weeks and 20-22 weeks of gestation, and the classification of these measurements according to type of delivery; and to investigate the change in the effect of delivery type on uterine artery flows on obstetric outcomes (maternal, fetal, neonatal outcomes).

Study Overview

• Status: Completed
• Conditions: Pregnancy Related
• Intervention / Treatment: Other: uterine artery doppler measurement

Detailed Description

The first and second trimester perinatal examination results performed by the same operator from pregnant women who have applied to the clinic since the first trimester are removed from the ViewPoint 6.0 server and database and their uterine artery doppler values (uterine artery PI and RI values, presence of uterine artery notch), placental location, gestational week of measurement, blood pressures, PAPP-A and hCG MoM values, obstetric results (type of birth, week, weight, ante-postpartum complications), data to be generated from other hospital records will be saved to the base

• Study Type: Observational
• Enrollment (Actual): 750

Contacts and Locations

Study Locations

• Turkey
  • Istanbul, Turkey, 33404
    • Kanuni Sultan Suleyman Training and Research Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 45 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Female

• Sampling Method: Probability Sample

Study Population

Patients who had uterine artery doppler measurements and delivered at 11-14 weeks and 20-22 weeks of pregnancy will be the study group. these patients; Doppler results will be classified according to pregnancy results, and the classification of these measurements according to type of delivery; and the effect of delivery on uterine artery flows on obstetric outcomes (maternal, fetal, neonatal outcomes) will be examined.

Description

Inclusion Criteria:

• Gestational age 11-14. applying to the outpatient clinic at week
• Single spontaneous pregnancy
• Having a first pregnancy (primigravid nullipar) or having given birth once (primipar) (first birth by vaginal route or cesarean)
• Result of previous pregnancy with live birth (term delivery without obstetric complication)
• No intrauterine growth restriction in the first pregnancy
• Women who gave birth by cesarean section were not placed due to caesarean indication due to placental location-invasion anomaly, maternal chronic disease (hypertension, diabetes, coronary artery disease, etc.), placental detachment.

Exclusion Criteria:

• Multiple pregnancies
• Pregnancies with assisted reproductive techniques
• Placental anomaly in previous pregnancy
• Maternal chronic hypertension, preeclampsia, history of diabetes
• Pregnant women who smoke
• The presence of fetal chromosomal or structural anomaly
• two or more cesarean sections
• Having undergone non-cesarean surgery (myomectomy, septum or polyp resection ... etc)
• Presence of uterine structural anomaly

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Uterine artery doppler measurements; Uterine artery doppler measurements will be made in the same patients at 11-14 weeks and 20-22 weeks of pregnancy. Doppler results will be classified according to pregnancy results and primary results will be doppler findings.	Other: uterine artery doppler measurement; The effect of delivery type on changes in uterine blood flow will be investigated. Doppler results groups will be defined according to the effect of deviations in uterine blood flow on neonatal and perinatal results.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Doppler results of 11-14 weeks of gestation in patients with previous cesarean section	uterine artery doppler values (uterine artery PI , presence of uterine artery notch)	10 months
Doppler results of 11-14 weeks of gestation in those who gave birth beforehand	uterine artery doppler values (uterine artery PI , presence of uterine artery notch)	10 months
Doppler results of 20-22 weeks of gestation in patients with previous cesarean section	uterine artery doppler values (uterine artery PI , presence of uterine artery notch)	10 months
Doppler results of 20-22 weeks of gestation in those who gave birth beforehand	uterine artery doppler values (uterine artery PI , presence of uterine artery notch)	10 months

Collaborators and Investigators

• Sponsor: Kanuni Sultan Suleyman Training and Research Hospital

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2016
• Primary Completion (Actual): January 1, 2020
• Study Completion (Actual): January 1, 2020

Study Registration Dates

• First Submitted: January 28, 2020
• First Submitted That Met QC Criteria: January 28, 2020
• First Posted (Actual): January 30, 2020

Study Record Updates

• Last Update Posted (Actual): January 30, 2020
• Last Update Submitted That Met QC Criteria: January 28, 2020
• Last Verified: January 1, 2020

More Information

Terms related to this study

• Keywords: obstetric outcomes; Uterine artery doppler; type of delivery
• Other Study ID Numbers: ATADEK-2020/00

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No