- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04597814
The Relationship Between the Tumor Markers and Interstitial Lung Disease
The serum levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 are often increased in interstitial lung disease patients.
This study was undertaken to investigate the source of these serum tumor markers.
Study Overview
Status
Intervention / Treatment
Detailed Description
The serum levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 are often increased in interstitial lung disease patients.
This study was undertaken to investigate the source of these serum tumor markers.We hypothesis that these tumor markers are released from the lung.
The broncholveolr lvge fluid levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 were measured in the interstitial lung disease patients before lung transplantation. The immunohistochemical test was performed in the specimen lung after lung transplantation.
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
-
-
Guangdong
-
Guangzhou, Guangdong, China, 520120
- The First Affiliated Hospital of Guangzhou Medical University
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria
1.Interstitial lung disease patients for lung transplantation
-
Exclusion Criteria:
- tumor
- Interstitial lung disease patients could not be performed by lung transplantation
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
interstitial lung disease patients
interstitial lung disease patients who need lung transplantation
|
No Intervention
|
non- interstitial lung disease patients
non- interstitial lung disease patients who need thoracic surgery to remove pneumatocele
|
No Intervention
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
serum levels of carcinoembryonic antigen (CEA)
Time Frame: 6months
|
serum levels of carcinoembryonic antigen (CEA)
|
6months
|
serum levels of carbohydrate antigen 19-9 (CA19-9)
Time Frame: 6months
|
serum levels of carbohydrate antigen 19-9 (CA19-9)
|
6months
|
serum levels of carbohydrate antigen 125(CA125)
Time Frame: 6months
|
serum levels of carbohydrate antigen 125(CA125)
|
6months
|
The alveolar lavage fluid levels of carcinoembryonic antigen (CEA)
Time Frame: 1 week
|
The alveolar lavage fluid levels of carcinoembryonic antigen (CEA)
|
1 week
|
The alveolar lavage fluid levels of carbohydrate antigen 19-9 (CA19-9)
Time Frame: 1 week
|
The alveolar lavage fluid levels of carbohydrate antigen 19-9 (CA19-9)
|
1 week
|
The alveolar lavage fluid levels of carbohydrate antigen 125
Time Frame: 1 week
|
The alveolar lavage fluid levels of carbohydrate antigen 125
|
1 week
|
The lung tissue levels of carcinoembryonic antigen (CEA)
Time Frame: 1 week
|
The lung tissue levels of carcinoembryonic antigen (CEA)
|
1 week
|
The lung tissue levels of carbohydrate antigen 19-9 (CA19-9)
Time Frame: 1 week
|
The lung tissue levels of carbohydrate antigen 19-9 (CA19-9)
|
1 week
|
The lung tissue levels of carbohydrate antigen 125
Time Frame: 1 week
|
The lung tissue levels of carbohydrate antigen 125
|
1 week
|
Collaborators and Investigators
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- yilunshen2020145
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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