- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04795232
Recovery Kinetics Following Change of Direction Training
October 6, 2023 updated by: Ioannis G. Fatouros, University of Thessaly
Recovery Kinetics Following Change of Direction (COD) Training in Soccer: Implications for Different COD Angles
This study aims at investigating the recovery kinetics of skeletal muscle damage, neuromuscular fatigue and performance following a single change of direction (COD) training session in competitive soccer players.
The impact of COD degrees will be also examined by comparing a 45o vs. 90o COD training session.
Ten male soccer players will perform a COD45 [A single training session including 2x(10x ~27.6m) sprints with two 45o COD in each sprint], a COD90 [A single training session including 2x(10x ~21.2m) sprints with two 90o COD in each sprint] and a Control trial (No intervention included, only daily measurements) in randomized, repeated measures, crossover design.
Assessments related to skeletal muscle damage, neuromuscular fatigue and performance will be performed prior to training session and daily for three consecutive days post-training, in each trial.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
Ten male soccer players will be included in this study.
Participants will be initially informed about the aim of study as well as the associated risks and benefits and subsequently will provide their signed consent form.
At baseline, they will undergo assessment of their anthropometrics (i.e.
body mass and body height), body composition (by DXA), physical conditioning status [maximal oxygen consumption (VO2max), Yo-Yo Intermittent Endurance test level 2 and Yo-Yo Intermittent Recovery test level 2] and daily dietary intake.
Thereafter, they will participate in two experimental trials and one control trial in a randomized, crossover, repeated measures design: i) COD45: Participants in this trial will perform a COD training session consisted of 2 sets of 10 x ~27.6m sprints with two 45o COD in each sprint and a resting period of 16 sec and 2:20 min between sprints and sets, respectively, ii) COD90: Participants in this trial will perform a COD training session consisted of 2 sets of 10 x ~21.2m sprints with two 90o COD in each sprint and a resting period of 16 sec and 2:20 min between sprints and sets, respectively, iii) Control: Participants in this trial will only participate in daily assessments to control for day to day variability in the depended variables (they will not receive any intervention).
Prior to each trial, participants will provide a resting blood sample (for the determination of blood lactate, white blood cell count and creatine kinase activity) and undergo assessment of their delayed onset of muscle soreness (DOMS), maximal voluntary isometric contraction (MVIC), countermovement jump [will be assessed using two force platforms at 1000 Hz and electromyography instrumentation (EMG)], isokinetic peak torque of knee extensors and flexors (will be assessed on an isokinetic dynamometer), agility (will be assessed using the Illinois test), 10m and 30m sprint time (will be assessed by using light cells) and repeated sprint ability (5x30m sprints will be performed with 25 sec rest in-between).
In COD45 and COD90 experimental trials, a blood sample will be collected immediately post-training for the determination of blood lactate concentration while assessment of DOMS, MVIC and countermovement jump will be performed at 1, 2 and 3 hours post-training.
In all trials assessment of DOMS, MVIC, countermovement jump (CMJ), isokinetic peak torque, agility and sprinting performance as well as determination of creatine kinase activity and white blood cell count will be performed at 24, 48 and 72 hours post-training.
A 7-day wash out period will applied between trials.
Study Type
Interventional
Enrollment (Actual)
10
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Panagiotis Tsimeas, PhD
- Phone Number: +30 24310 47067
- Email: ptsimeas@pe.uth.gr
Study Locations
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Trikala, Greece, 42100
- SmArT LABORATORY, SCHOOL OF PHYSICAL EDUCATION & SPORTS SCIENCES, UNIVERSITY OF THESSALY
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Trikala, Greece, 42100
- SMART LAB, Department of Physical Education and Sports Science, University of Thessaly.
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 35 years (Adult)
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- Soccer players participating in at least 5 training sessions per week and 1official match
- Participation at a competitive level for at least 4 years
- Free of musculoskeletal injuries
- No use of ergogenic supplements or medication
- Non-smokers
Exclusion Criteria:
- Musculoskeletal injury
- Use of alcohol, caffeine and any type of ergogenic supplements or medication during the course of the study
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Other
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
No Intervention: Control
Participants in this arm will receive no intervention
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|
Experimental: COD45
Participants in this arm will participate in a COD training session consisted of 45 degrees changes of direction
|
Participants will perform 2 sets of 10 sprints.
The total distance for each sprint will be 27.6 meters and will include two changes of direction of 45 degrees.
The recovery time will be 16 seconds between sprints and 2.20 minutes between sets
|
Experimental: COD90
Participants in this arm will participate in a COD training session consisted of 90 degrees changes of direction
|
Participants will perform 2 sets of 10 sprints.
The total distance for each sprint will be 21.2 meters and will include two changes of direction of 90 degrees.
The recovery time will be 16 seconds between sprints and 2.20 minutes between sets
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Change in creatine kinase activity
Time Frame: At baseline, at 24, 48 and 72 hours after change of direction training session
|
Creatine kinase activity will be measured in plasma
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At baseline, at 24, 48 and 72 hours after change of direction training session
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Change in white blood cell count
Time Frame: At baseline, at 24, 48 and 72 hours after change of direction training session
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White blood cell count will be measured by using an automatic blood analyzer
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At baseline, at 24, 48 and 72 hours after change of direction training session
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Change in delayed onset of muscle soreness
Time Frame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
|
Muscle soreness will be assessed by palpation of the muscle belly and the distal region
|
At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Change in isometric peak torque
Time Frame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
|
Isometric peak torque will be assessed on an isokinetic dynamometer
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At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Change in fatigue index of maximal voluntary isometric contraction during 10 seconds
Time Frame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Fatigue rate will be determined by calculating the percent drop of peak torque between the first and the last three seconds of a 10-second maximal isometric contraction
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At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Change in isokinetic peak torque of knee extensors
Time Frame: At baseline, at 24, 48 and 72 hours after change of direction training session
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Isokinetic peak torque will be assessed on an isokinetic dynamometer in both limbs
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At baseline, at 24, 48 and 72 hours after change of direction training session
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Change in isokinetic peak torque of knee flexors
Time Frame: At baseline, at 24, 48 and 72 hours after change of direction training session
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Isokinetic peak torque will be assessed on an isokinetic dynamometer in both limbs
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At baseline, at 24, 48 and 72 hours after change of direction training session
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Change in countermovement jump height
Time Frame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Countermovement jump height will be assessed by using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the jump height for each leg
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At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Change in ground reaction force during countermovement jump
Time Frame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Ground reaction force will be assessed by using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the jump height for each leg
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At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Change in peak power during countermovement jump
Time Frame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Peak power will be assessed using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the jump height for each leg
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At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Change in mean power during countermovement jump
Time Frame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Mean power will be assessed using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the jump height for each leg
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At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Change in vertical stiffness during countermovement jump
Time Frame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Vertical stiffness will be assessed using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the jump height for each leg
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At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Change in peak rate of force development during countermovement jump
Time Frame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Peak rate of force development will be assessed using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the jump height for each leg
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At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Change in peak normalized electromyography (EMG) during the eccentric and concentric phases of the countermovement jump
Time Frame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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EMG data will be collected wirelessly at 2000 Hz using a Myon MA-320 EMG system (Myon AG, Switzerland) for the vastus lateralis, biceps femoris, gastrocnemius and gluteus maximus muscles.
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At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Change in mean normalized electromyography (EMG) during the eccentric and concentric phases of the countermovement jump
Time Frame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
|
EMG data will be collected wirelessly at 2000 Hz using a Myon MA-320 EMG system (Myon AG, Switzerland) for the vastus lateralis, biceps femoris, gastrocnemius and gluteus maximus muscles.
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At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
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Change in repeated sprint ability
Time Frame: At baseline, at 24, 48 and 72 hours after change of direction training session
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Repeated sprint ability will be tested using 5x30 m sprints with 25 seconds rest in-between
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At baseline, at 24, 48 and 72 hours after change of direction training session
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Change in sprint time of 10m
Time Frame: At baseline, at 24, 48 and 72 hours after change of direction training session
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10m sprint time will be assessed using light cells
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At baseline, at 24, 48 and 72 hours after change of direction training session
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Change in sprint time of 30m
Time Frame: At baseline, at 24, 48 and 72 hours after change of direction training session
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30m sprint time will be assessed using light cells
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At baseline, at 24, 48 and 72 hours after change of direction training session
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Change in agility
Time Frame: At baseline, at 24, 48 and 72 hours after change of direction training session
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Agility will be assessed using the illinois agility test.
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At baseline, at 24, 48 and 72 hours after change of direction training session
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Change in field activity during the change of direction training session
Time Frame: During the change of direction training session
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Field activity will be continuously monitored during the change of direction training session by using global positioning system (GPS)
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During the change of direction training session
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Change in heart rate during the change of direction training session
Time Frame: During the change of direction training session
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Heart rate will be continuously monitored during the change of direction training session by using heart rate monitors.
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During the change of direction training session
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Change in blood lactate concentration
Time Frame: At baseline and immediately post change of direction training session
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Blood lactate will be measured using a lactate plus system
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At baseline and immediately post change of direction training session
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Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Body mass
Time Frame: At baseline
|
Body mass will me measured on a beam balance with stadiometer
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At baseline
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Body height
Time Frame: At baseline
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Body height will me measured on a beam balance with stadiometer
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At baseline
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Body fat
Time Frame: At baseline
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Body fat will be assessed by using Dual-emission X-ray absorptiometry
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At baseline
|
Lean body mass
Time Frame: At baseline
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Lean body mass will be assessed by using Dual-emission X-ray absorptiometry
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At baseline
|
Maximal oxygen consumption (VO2max)
Time Frame: At baseline
|
VO2max will be measured by open circuit spirometry via breath by breath method
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At baseline
|
Yo-Yo Intermittent Endurance Test level 2 performance
Time Frame: At baseline
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At baseline
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Yo-Yo Intermittent Recovery Test level 2 performance
Time Frame: At baseline
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At baseline
|
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Dietary intake
Time Frame: At baseline
|
Dietary intake will be assessed over a 7-day period by using diet recalls
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At baseline
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Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Study Director: Ioannis G Fatouros, Prof, University of Thessaly, Department of Physical Education and Sport Science
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
April 1, 2021
Primary Completion (Actual)
September 30, 2021
Study Completion (Actual)
June 30, 2023
Study Registration Dates
First Submitted
March 9, 2021
First Submitted That Met QC Criteria
March 9, 2021
First Posted (Actual)
March 12, 2021
Study Record Updates
Last Update Posted (Estimated)
October 9, 2023
Last Update Submitted That Met QC Criteria
October 6, 2023
Last Verified
October 1, 2023
More Information
Terms related to this study
Other Study ID Numbers
- Recovery-COD Training-UTH
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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