Fatigability and Cognitive Demand With Aging

April 27, 2026 updated by: University of Oklahoma
This study will determine the influence of a cognitive task performed during fatiguing contractions.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Individuals will participate in one familiarization session followed by 3 randomized experimental sessions (crossover design).

Study Type

Interventional

Enrollment (Actual)

40

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Oklahoma
      • Norman, Oklahoma, United States, 73071
        • University of Oklahoma

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 90 years (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Healthy individuals aged between 18-35 and 65-90

Exclusion Criteria:

  • Metal implants or joint replacement. neuromuscular disease

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Single Group Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: young men
Individuals will participate in 1 familiarization and 3 test sessions
Behavioral: cognitive task
cognitive task
Experimental: young women
Individuals will participate in 1 familiarization and 3 test sessions
Behavioral: cognitive task
cognitive task
Experimental: older men
Individuals will participate in 1 familiarization and 3 test sessions
Behavioral: cognitive task
cognitive task
Experimental: older women
Individuals will participate in 1 familiarization and 3 test sessions
Behavioral: cognitive task
cognitive task

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
force
Time Frame: Each session will take approximately 2-3 hours (total of 4 test sessions)
Change in force of the arm muscles will be evaluated with a custom made device during each test session
Each session will take approximately 2-3 hours (total of 4 test sessions)
anxiety levels
Time Frame: Each session will take approximately 2-3 hours (total of 4 test sessions
changes in anxiety levels quantified with a questionnaire
Each session will take approximately 2-3 hours (total of 4 test sessions
arterial pressure
Time Frame: Each session will take approximately 2-3 hours (total of 4 test sessions
changes in arterial pressure will be quantified with a non-invasive device (finometer)
Each session will take approximately 2-3 hours (total of 4 test sessions
fatigue
Time Frame: Each session will take approximately 2-3 hours (total of 4 test sessions
changes in fatigue will be assessed with questionnaires
Each session will take approximately 2-3 hours (total of 4 test sessions

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Oklahoma

Investigators

  • Principal Investigator: Hugo Pereira, PhD, University of Oklahoma

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 11, 2021

Primary Completion (Actual)

August 15, 2025

Study Completion (Actual)

April 27, 2026

Study Registration Dates

First Submitted

September 3, 2021

First Submitted That Met QC Criteria

November 4, 2021

First Posted (Actual)

November 16, 2021

Study Record Updates

Last Update Posted (Actual)

May 1, 2026

Last Update Submitted That Met QC Criteria

April 27, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 13406P

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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