Can Exposure to Inclusive Virtual Art Decrease Pain and Social Disconnection Among Individuals Living With Chronic Pain?

April 17, 2025 updated by: University of California, Davis
The proposed study is an experimental intervention to test for the effects of exposure to art by means of a virtual museum visit. It examines the fundamental question of whether exposure to virtual art can alleviate pain. Google Arts & Culture has digitized the collections of over 2,000 museums, art galleries, and other cultural institutions. The platform is free and allows 'visitors' to explore art from around the world. For this study, the PIs have chosen artwork from this collection and created a virtual museum gallery such that research participants will visit the museum with or without art (i.e., we will remove all art from the virtual galleries). In addition, we hypothesize that individuals primed to experience social connection prior to art exposure will experience lower perceived social disconnection and pain than those who are not primed.

Study Overview

Detailed Description

Research Design: 2 (virtual artwork exposure: present, absent) x 2 (prime: social connection prime: high, low) factorial experiment with a hanging control group (4 cells plus 1 control group, for a total of 5 cells) and 2 repeated measures. A priori power analysis using G*Power showed that the required sample size for a 5-group repeated measures experiment with 2 measurement times with 1-B error probability = .80 that expected small effect with a size of d = .10 and a significance level of p = .05 was a total of 305 participants (61 participants per cell).

Eligible individuals will be offered informed consent documentation via the StudyPages platform and then will be randomized to their study group:

  1. Artwork present + Social connection prime high
  2. Artwork present + Social connection prime low
  3. Artwork absent + Social connection prime high
  4. Artwork absent + Social connection prime low
  5. Hanging control group - no exposure to any independent variables (i.e. artwork: present or absent; social connection prime: high or low)

Participants will fill out pre-intervention scales (pain intensity and unpleasantness; perceived social disconnection) prior to their virtual museum experience. Participants will then visit a virtual art museum gallery for 10 minutes or receive no exposure if they are in the hanging control group. In the artwork present condition, the virtual museum will feature paintings as part of an exhibition. In the artwork absent condition, paintings will be removed and thus the virtual museum will be empty. In the high social connection prime condition participants will be assigned to write an essay about a person and situation that made them feel valued, seen, and heard. In the low social connection prime condition participants will be assigned to write about a person and situation that made them feel ignored and not very valued. After 10 minutes within their condition participants will complete a post-intervention survey.

In addition, written responses to the social connection primes and museum visit data (e.g., user movement, object interaction, and perceptions about artwork in the museum) will be collected and analyzed.

Study Type

Interventional

Enrollment (Actual)

311

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

    • California
      • Sacramento, California, United States, 95817
        • University of California, Davis

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • read and write in English language
  • chronic moderate to severe pain (≥ 6 months in duration; ≥ 4 in response to the question, "on average this week my pain intensity has been?" on a 0-10 NRS)
  • lonely (≥ 4 on the 3-item Loneliness Scale)
  • access to an electronic device with internet connection in order to participate in the study

Exclusion Criteria:

  • dementia
  • adults unable to consent

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Factorial Assignment
  • Masking: Triple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Artwork present + social connection high
Individuals participate in an exercise to prime a feeling of high social connection and then explore a virtual museum exhibit with artwork for 10 minutes
A virtual museum exhibit with a curated selection of artworks
Participants will identify a person from their life that makes them feel socially connected and then write (1) about that person and (2) an experience they had with that person that made them feel socially connected.
Experimental: Artwork present + social connection low
Individuals participate in an exercise to prime a feeling of low social connection and then explore a virtual museum exhibit with artwork for 10 minutes
A virtual museum exhibit with a curated selection of artworks
Participants will identify a person from their life that makes them feel socially disconnected and then write (1) about that person and (2) an experience they had with that person that made them feel socially disconnected.
Experimental: Artwork absent + social connection high
Individuals participate in an exercise to prime a feeling of high social connection and then explore a virtual museum exhibit with no artwork for 10 minutes
Participants will identify a person from their life that makes them feel socially connected and then write (1) about that person and (2) an experience they had with that person that made them feel socially connected.
The same virtual museum exhibit space as the 'Artwork present' condition but with all of the artworks removed from the walls
Active Comparator: Artwork absent + social connection low
Individuals participate in an exercise to prime a feeling of low social connection and then explore a virtual museum exhibit with no artwork for 10 minutes
Participants will identify a person from their life that makes them feel socially disconnected and then write (1) about that person and (2) an experience they had with that person that made them feel socially disconnected.
The same virtual museum exhibit space as the 'Artwork present' condition but with all of the artworks removed from the walls
No Intervention: Hanging control group
Individuals will receive no exposure to any independent variables (i.e. artwork: present or absent; social connection prime: high or low) for 10 minutes before completing their final survey.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Social disconnection
Time Frame: Post-intervention (immediately)/Day 1
Social disconnection scale; 12 items; scored 1 (not at all) - 5 (very much); range 12-60
Post-intervention (immediately)/Day 1

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Pain unpleasantness
Time Frame: Post-intervention (immediately)/Day 1
Numerical rating scale (NRS) score of 0 "not unpleasant" - 10 "Most unpleasant sensation imaginable ("intolerable")"
Post-intervention (immediately)/Day 1
Pain intensity
Time Frame: Post-intervention (immediately)/Day 1
Numerical rating scale (NRS) score of 0 "no pain" - 10 "worst pain imaginable"
Post-intervention (immediately)/Day 1
Change in pain during intervention
Time Frame: Post-intervention (immediately)/Day 1
Did you experience any pain relief during the museum experience? 1=Yes/0=No
Post-intervention (immediately)/Day 1
Percent change in pain during intervention
Time Frame: Post-intervention (immediately)/Day 1
If "Yes", what percent pain relief did you receive? 0%-100%
Post-intervention (immediately)/Day 1
Perceptions of the artwork related to the positivity of the social world
Time Frame: Post-intervention (immediately)/Day 1
The artwork in the museum made me feel (7-point likert scale anchored by "Negative about the social world" and "Positive about the social world")
Post-intervention (immediately)/Day 1
Perceptions of the artwork related to connection to the social world
Time Frame: Post-intervention (immediately)/Day 1
The artwork in the museum made me feel (7-point likert scale anchored by "Disconnected to the social world" and "Connected to the social world")
Post-intervention (immediately)/Day 1
Perceptions of the artwork related to inclusion in the social world
Time Frame: Post-intervention (immediately)/Day 1
The artwork in the museum made me feel (7-point likert scale anchored by "Excluded from the social world" and "Included in the social world")
Post-intervention (immediately)/Day 1
Perceptions of the artwork related to positivity of social relationships
Time Frame: Post-intervention (immediately)/Day 1
The artwork in the museum made me feel (7-point likert scale anchored by "Negative about my social relationships" and "Positive about my social relationships"
Post-intervention (immediately)/Day 1

Other Outcome Measures

Outcome Measure
Measure Description
Time Frame
Museum visit data - User Movement
Time Frame: During intervention
Each user's avatar movement will be calculated in an x, y, z axis within the structure of the virtual museum.
During intervention
Museum Visit Data - Object Interaction
Time Frame: During intervention
Number of clicks on virtual museum artwork. Clicking gives users access to additional information about each piece of art.
During intervention

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 7, 2022

Primary Completion (Actual)

January 6, 2023

Study Completion (Actual)

January 6, 2023

Study Registration Dates

First Submitted

December 16, 2021

First Submitted That Met QC Criteria

April 4, 2022

First Posted (Actual)

April 5, 2022

Study Record Updates

Last Update Posted (Actual)

April 23, 2025

Last Update Submitted That Met QC Criteria

April 17, 2025

Last Verified

April 1, 2025

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 1811205

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Chronic Pain

Clinical Trials on Artwork present

Subscribe