Post-ICU Consultation : a Time to Discuss Advance Directives (CoPRADA) (CoPRADA)

Post-ICU Consultation : a Time to Discuss Advance Directives

The aim of this study is to assess the possibility of discussing advance directives during post-intensive care consultation.

Study Overview

• Status: Completed
• Conditions: Advance Care Planning; Post Intensive Care Syndrome; Advance Directives

Detailed Description

After a stay in intensive care units (ICU), patients can experience physical, psychological and cognitive impairments. To assess this post intensive care syndrom (PICS), post-ICU consultation have been developed.

Since 5 year mortality is higher in ICU survivors, it might be interesting to address those patients' views relating to illness and end of life through a discussion on advance directives (AD), during post-ICU consultation.

However, the development of these consultations being recent, it has not yet been assessed whether this consultations might be a suitable time to discuss AD and the intensivit a suitable interlocutor.

• Study Type: Observational
• Enrollment (Actual): 40

Contacts and Locations

Study Locations

• France
  • Brest, France, 29200
    • CHU Brest

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Probability Sample

Study Population

All patients with at least 48 hours of mechanical ventilation and/or a 5 days stay in ICU, and then summoned to post-ICU consultation

Description

Inclusion Criteria:

• Patients with 48 hours of mechanical ventilation
• Patients with a 5 days stay in ICU

Exclusion Criteria:

• Patients with therapeutic limitation discussed during their ICU stay
• Geographical remotness to come to the post-ICU consultation
• Minor patients
• Patient not affiliated to the social security scheme

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
ICU patients with > 48h mechanical ventilation and/or > 5 days stay in ICU

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of patients willing to discuss AD after an ICU stay	Number of patient willing to discussion AD after ICU stay will be observed	1 year

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of patients knowing about AD before their ICU stay	Number of patient knowing before AD before ICU stay will be observed	1 year
Factors influencing the writing of AD after an ICU stay	Factors such as lenght of stay in ICU, lenght of hospitalisation, duration of mechanical ventilation /sedation and the existence of PTSD (PCLS) or anxiety/ depression (HADS) will be evaluated and their influence on the completion of AD	1 year
Evaluation of the privileged interlocutor to discuss AD	The privileged interlocutor to discuss AD will be observed	1 year
Evaluation of the privileged interlocutor to complete AD	The privileged interlocutor to complete AD will be observed	1 year

Collaborators and Investigators

• Sponsor: University Hospital, Brest

Publications and helpful links

General Publications

• Rousseau AF, Prescott HC, Brett SJ, Weiss B, Azoulay E, Creteur J, Latronico N, Hough CL, Weber-Carstens S, Vincent JL, Preiser JC. Long-term outcomes after critical illness: recent insights. Crit Care. 2021 Mar 17;25(1):108. doi: 10.1186/s13054-021-03535-3.
• Andreu P, Dargent A, Large A, Meunier-Beillard N, Vinault S, Leiva-Rojas U, Ecarnot F, Prin S, Charles PE, Fournel I, Rigaud JP, Quenot JP. Impact of a stay in the intensive care unit on the preparation of Advance Directives: Descriptive, exploratory, qualitative study. Anaesth Crit Care Pain Med. 2018 Apr;37(2):113-119. doi: 10.1016/j.accpm.2017.05.007. Epub 2017 Aug 4.
• Lone NI, Walsh TS. Impact of intensive care unit organ failures on mortality during the five years after a critical illness. Am J Respir Crit Care Med. 2012 Oct 1;186(7):640-7. doi: 10.1164/rccm.201201-0059OC. Epub 2012 Jul 26.

Study record dates

Study Major Dates

• Study Start (Actual): December 9, 2021
• Primary Completion (Actual): December 9, 2022
• Study Completion (Actual): December 9, 2022

Study Registration Dates

• First Submitted: April 5, 2023
• First Submitted That Met QC Criteria: April 17, 2023
• First Posted (Actual): April 18, 2023

Study Record Updates

• Last Update Posted (Actual): April 18, 2023
• Last Update Submitted That Met QC Criteria: April 17, 2023
• Last Verified: April 1, 2023

More Information

Terms related to this study

• Keywords: Intensive Care; Advance directives; Post Intensive Care syndrome; Post Intensive Care consultation
• Additional Relevant MeSH Terms: Pathologic Processes; Disease; Syndrome
• Other Study ID Numbers: 29BRC21.0335 - CoPRADA

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No