Prediction of Hypotension During Induction of General Anesthesia

August 2, 2024 updated by: Ain Shams University

Assessment of Ultrasonographic Carotid Artery Corrected Flow Time and Internal Jugular Vein Collapsibility Index in Prediction of Hypotension During Induction of General Anesthesia

Post induction hypotension is closely related to postoperative complications. Patients are at high risk of hypotension due to preexisting hypovolemia and the vasodilatory effects of induction agents. Ultrasonographic measurement of the Carotid artery corrected flow time and internal jugular vein collapsibility index may predict post induction hypotension.

Study Overview

Status

Enrolling by invitation

Conditions

Intervention / Treatment

Detailed Description

  • Type of Study: Observational Prospective Cohort Design.
  • Study Setting and ethical consideration: The approval of the Scientific Research Ethics Committee of the Faculty of Medicine, Ain Shams University will be obtained before starting work on the study. This study will be conducted in operating theatres of Ain Shams University Hospitals. Informed written consents to participate will be obtained from the patients.
  • Study Period: One year (October 2023-October 2024)
  • Study Population: Adult patient undergoing elective surgeries.

Study Type

Observational

Enrollment (Estimated)

70

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
    • Abbassia
      • Cairo, Abbassia, Egypt, 7154411
        • Ain shams university

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Probability Sample

Study Population

Adult patient undergoing elective surgeries.

Description

Inclusion Criteria:

  • 1- Patients of American Society of Anesthesiologists (ASA) physical status I to II of both genders.

    2- Aged 18-65 years. 3- Elective surgeries under general anesthesia. 4- BMI less than 40.

Exclusion Criteria:

  • Patients with

    1. Renal diseases.
    2. Hepatic diseases.
    3. ASA scores of 3-4.
    4. The presence of a left ventricular ejection fraction less than 50%.
    5. Age under 18 years old.
    6. Patient refusal.
    7. Coronary heart disease.
    8. Cardiac disease including cardiomyopathy and mild to severe valve disease.
    9. Pulmonary hypertension.
    10. Peripheral arterial disease.
    11. Preoperative cervical vascular ultrasound abnormalities including plaque, stenosis and anatomical variation.
    12. Any previous neck surgery or trauma.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
the predictive value of the carotid Ftc for prediction of hypotension.
Time Frame: one year
to investigate the reliability of preanesthetic ultrasound measurements of the carotid artery FTc and the internal jugular vein collapsibility index in predicting hypotension during the induction of general anesthesia
one year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ain Shams University

Investigators

  • Principal Investigator: Marina George, MD candidate, Ain shams university

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

September 24, 2023

Primary Completion (Estimated)

August 17, 2024

Study Completion (Estimated)

August 17, 2024

Study Registration Dates

First Submitted

October 5, 2023

First Submitted That Met QC Criteria

October 5, 2023

First Posted (Actual)

October 11, 2023

Study Record Updates

Last Update Posted (Estimated)

August 5, 2024

Last Update Submitted That Met QC Criteria

August 2, 2024

Last Verified

September 1, 2023

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • FMASU MD205/2023

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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