Study of Social Cognition Processes With Multimodal MRI on Healthy Adult Patients.

The study of higher cognitive functions (learning, memory, language, reasoning, decision making) in humans constitutes an interdisciplinary field, which combines neurobiological and neurological, neuropsychological, as well as linguistic and artificial intelligence skills. Historically, the study of patients with cerebrovascular lesions or brain pathologies associated with primary and/or cognitive deficits has produced fundamental knowledge in this area. The development of modern non-invasive investigation techniques of the human brain - such as Structural Magnetic Resonance Imaging (MRI), Diffusion Tensor Imaging, Functional Magnetic Resonance Imaging (fMRI), Positron emission (PET), the study of event-related electrophysiological potentials (ERP) or magneto-encephalography (MEG) - has made it possible to carry out similar studies on healthy subjects, as well as the in-vivo analysis of adaptive and plastic mechanisms of the human brain. Recently, the interest of cognitive neuroscience - this is the name taken by this vast interdisciplinary sector which aims to understand the neural mechanisms underlying human cognitive processes - has been oriented towards the study of decision making in social contexts. Knowledge of the mechanisms underlying these processes is fundamental for the most complete description of the biological bases of human behavior and above all for the optimal development of treatments for brain pathologies, whether surgical, pharmacological or rehabilitation in general.

Study Overview

• Status: Completed
• Conditions: Social Cognition
• Intervention / Treatment: Diagnostic test: study of higher cognitive functions

• Study Type: Observational
• Enrollment (Actual): 27

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Probability Sample

Study Population

Behavioral study with neuro-anatomical functional correlates consisting of cognitive activation experiments during functional magnetic resonance imaging, with observation of images of a social nature and decision making in an individual or social context.

Description

Inclusion Criteria:

• Age between 18 and 35 years old; Monolingual native speakers of Italian; Absence of neurological or psychiatric pathologies that could interfere with carrying out the exam.

Exclusion Criteria:

• Clinical and/or anamnestic evidence of significant neuropsychiatric or systemic pathologies; Previous head trauma with loss of consciousness

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
behavioral study with neuroanatomical functional correlates consisting of cognitive activation experiments during functional magnetic resonance imaging	1 year

Collaborators and Investigators

• Sponsor: IRCCS San Raffaele

Study record dates

Study Major Dates

• Study Start (Actual): April 22, 2010
• Primary Completion (Actual): October 28, 2010
• Study Completion (Actual): October 28, 2010

Study Registration Dates

• First Submitted: December 1, 2023
• First Submitted That Met QC Criteria: December 1, 2023
• First Posted (Estimated): December 11, 2023

Study Record Updates

• Last Update Posted (Estimated): December 11, 2023
• Last Update Submitted That Met QC Criteria: December 1, 2023
• Last Verified: December 1, 2023

More Information

Terms related to this study

• Other Study ID Numbers: SOCIOCOGN

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No