Autogenous Grafts for Anterior Maxillary Horizontal Ridge Augmentation

Autogenous Inlay Versus Onlay Grafts for Anterior Maxillary Horizontal Ridge Augmentation

The aim of the study was to compare efficacy of autogenous onlay and inlay grafts for anterior maxillary horizontal ridge augmentation.

Study Overview

• Status: Completed
• Conditions: Alveolar Ridge Augmentation
• Intervention / Treatment: Procedure: Horizontal ridge augmentation by symphyseal bone block placed and fixed buccally as onlay graft; Procedure: Horizontal ridge augmentation by symphyseal bone block interpositioned in space created between buccal and lingual cortex as inlay graft

Detailed Description

Autogenous block graft has been used as onlay thin cortical shell and cortico-cancellous particles. The thin cortical shell acts as an autogenous biological membrane that will resist resorption and stabilize the small pieces of particulate bone. The bone block is screwed-in at a distance from the recipient site by means of titanium bone screws, and then the free space under the shell is filled with the particulate bone.

The resultant augmentation somehow resembles an iliac graft, with thick internal cancellous bone and a thin external cortical layer. This leads to an ideal graft, with a high regenerative capacity comparable to iliac bone and a stable regenerated volume with optimum osseointegration potential close to that of mandibular block grafts.

Interpositional grafts have been successfully established in restoring vertical bone height . However much less evidence is present on its use for horizontal augmentation. It is the purpose of this study to assess the efficacy of autogenous onlay corticocancellous block grafts for anterior maxillary horizontal ridge augmentation as compared to onlay block grafts.

• Study Type: Interventional
• Enrollment (Actual): 14
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Egypt
  • Mansoura, Egypt
    • Mansoura U

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

1. Patients with missing upper anterior tooth / teeth with horizontal ridge dimension range from 2 to 5 mm (measured 2mm below alveolar crest).
2. Adequate vertical height.
3. Having good oral hygiene.
4. being healthy, with no systemic diseases that might contraindicate receiving a dental implant
5. Patients were able to comply with the follow-up and maintenance program

Exclusion Criteria:

1. Presence of local infection or lesions at site of interest.
2. Dental history of bruxism, or other parafunctional habits.
3. Uncooperative patients.
4. Current chemotherapy or radiotherapy.
5. Patients with aggressive periodontal disease

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Triple

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Group A; Seven horizontal anterior maxillary ridge augmentation was done with symphyseal autogenous bone block, which was placed buccally as onlay graft.	Procedure: Horizontal ridge augmentation by symphyseal bone block placed and fixed buccally as onlay graft; autogenous bone block harvested from chin area using piezosurgery and fixed buccally in deficient area with fixation screws
Experimental: Group B; Seven horizontal anterior maxillary ridge augmentation was done with symphyseal autogenous bone block, which was interpositioned in space created between buccal and lingual cortex as inlay graft.	Procedure: Horizontal ridge augmentation by symphyseal bone block interpositioned in space created between buccal and lingual cortex as inlay graft; autogenous bone block harvested from chin area using piezosurgery and fixed in bone split created at deficient area with fixation screws

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
horizontal ridge augmentation	CBCT to assess bone gain in mm	12 months

Collaborators and Investigators

• Sponsor: Mansoura University

Study record dates

Study Major Dates

• Study Start (Actual): September 1, 2020
• Primary Completion (Actual): September 15, 2022
• Study Completion (Actual): May 26, 2023

Study Registration Dates

• First Submitted: December 20, 2023
• First Submitted That Met QC Criteria: January 4, 2024
• First Posted (Actual): January 16, 2024

Study Record Updates

• Last Update Posted (Actual): January 16, 2024
• Last Update Submitted That Met QC Criteria: January 4, 2024
• Last Verified: January 1, 2024

More Information

Terms related to this study

• Keywords: onlay grafting; inlay grafting
• Other Study ID Numbers: A08040820

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No